Genome Sequence of a Serotype M28 Strain of Group A Streptococcus: Potential New Insights into Puerperal Sepsis and Bacterial Disease Specificity NM Green, S Zhang, SF Porcella, MJ Nagiec, KD Barbian, SB Beres, ... The Journal of infectious diseases 192 (5), 760-770, 2005 | 294 | 2005 |
Molecular genetic anatomy of inter-and intraserotype variation in the human bacterial pathogen group A Streptococcus SB Beres, EW Richter, MJ Nagiec, P Sumby, SF Porcella, FR DeLeo, ... Proceedings of the National Academy of Sciences 103 (18), 7059-7064, 2006 | 245 | 2006 |
Regulation of cell signaling dynamics by the protein kinase-scaffold Ste5 N Hao, S Nayak, M Behar, RH Shanks, MJ Nagiec, B Errede, J Hasty, ... Molecular cell 30 (5), 649-656, 2008 | 168 | 2008 |
Quantitative phosphoproteomic analysis reveals system-wide signaling pathways downstream of SDF-1/CXCR4 in breast cancer stem cells T Yi, B Zhai, Y Yu, Y Kiyotsugu, T Raschle, M Etzkorn, HC Seo, M Nagiec, ... Proceedings of the National Academy of Sciences 111 (21), E2182-E2190, 2014 | 156 | 2014 |
mTORC1 promotes metabolic reprogramming by the suppression of GSK3-dependent Foxk1 phosphorylation L He, AP Gomes, X Wang, SO Yoon, G Lee, MJ Nagiec, S Cho, A Chavez, ... Molecular cell 70 (5), 949-960. e4, 2018 | 145 | 2018 |
Emergence of a bacterial clone with enhanced virulence by acquisition of a phage encoding a secreted phospholipase A2 I Sitkiewicz, MJ Nagiec, P Sumby, SD Butler, C Cywes-Bentley, ... Proceedings of the National Academy of Sciences 103 (43), 16009-16014, 2006 | 103 | 2006 |
Dynamic incorporation of histone H3 variants into chromatin is essential for acquisition of aggressive traits and metastatic colonization AP Gomes, D Ilter, V Low, A Rosenzweig, ZJ Shen, T Schild, MA Rivas, ... Cancer Cell 36 (4), 402-417. e13, 2019 | 89 | 2019 |
ERK2 regulates epithelial-to-mesenchymal plasticity through DOCK10-dependent Rac1/FoxO1 activation S Shin, GR Buel, MJ Nagiec, MJ Han, PP Roux, J Blenis, SO Yoon Proceedings of the National Academy of Sciences 116 (8), 2967-2976, 2019 | 82 | 2019 |
Rap1-GTPases control mTORC1 activity by coordinating lysosome organization with amino acid availability AP Mutvei, MJ Nagiec, JC Hamann, SG Kim, CT Vincent, J Blenis Nature Communications 11 (1), 1416, 2020 | 69 | 2020 |
Altered propionate metabolism contributes to tumour progression and aggressiveness AP Gomes, D Ilter, V Low, S Drapela, T Schild, E Mullarky, J Han, I Elia, ... Nature metabolism 4 (4), 435-443, 2022 | 62 | 2022 |
Checkpoints in a yeast differentiation pathway coordinate signaling during hyperosmotic stress MJ Nagiec, HG Dohlman PLoS genetics 8 (1), e1002437, 2012 | 59 | 2012 |
Analysis of a novel prophage-encoded group A Streptococcus extracellular phospholipase A2 MJ Nagiec, B Lei, SK Parker, ML Vasil, M Matsumoto, RM Ireland, ... Journal of Biological Chemistry 279 (44), 45909-45918, 2004 | 51 | 2004 |
Crystal structure of group A streptococcus Mac-1: insight into dimer-mediated specificity for recognition of human IgG J Agniswamy, MJ Nagiec, M Liu, P Schuck, JM Musser, PD Sun Structure 14 (2), 225-235, 2006 | 35 | 2006 |
Signal inhibition by a dynamically regulated pool of monophosphorylated MAPK MJ Nagiec, PC McCarter, JB Kelley, G Dixit, TC Elston, HG Dohlman Molecular biology of the cell 26 (18), 3359-3371, 2015 | 28 | 2015 |
Balancing lysosome abundance in health and disease AP Mutvei, MJ Nagiec, J Blenis Nature Cell Biology 25 (9), 1254-1264, 2023 | 26 | 2023 |
Regulation of GSK3 cellular location by FRAT modulates mTORC1-dependent cell growth and sensitivity to rapamycin L He, DL Fei, MJ Nagiec, AP Mutvei, A Lamprakis, BY Kim, J Blenis Proceedings of the National Academy of Sciences 116 (39), 19523-19529, 2019 | 25 | 2019 |
Combined computational and experimental analysis reveals mitogen-activated protein kinase–mediated feedback phosphorylation as a mechanism for signaling specificity N Hao, N Yildirim, MJ Nagiec, SC Parnell, B Errede, HG Dohlman, ... Molecular biology of the cell 23 (19), 3899-3910, 2012 | 23 | 2012 |
Positive roles for negative regulators in the mating response of yeast JR Houser, E Ford, MJ Nagiec, B Errede, TC Elston Molecular systems biology 8 (1), 586, 2012 | 20 | 2012 |
Proper protein glycosylation promotes mitogen-activated protein kinase signal fidelity EC Lien, MJ Nagiec, HG Dohlman Biochemistry 52 (1), 115-124, 2013 | 15 | 2013 |
Genome-wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase JR Ferrarone, J Thomas, AM Unni, Y Zheng, MJ Nagiec, EE Gardner, ... Proceedings of the National Academy of Sciences 121 (21), e2403685121, 2024 | 3 | 2024 |