| Familial Alzheimer's disease–linked presenilin 1 variants elevate Aβ1–42/1–40 ratio in vitro and in vivo DR Borchelt, G Thinakaran, CB Eckman, MK Lee, F Davenport, ... Neuron 17 (5), 1005-1013, 1996 | 2143 | 1996 |
| Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo G Thinakaran, DR Borchelt, MK Lee, HH Slunt, L Spitzer, G Kim, ... Neuron 17 (1), 181-190, 1996 | 1358 | 1996 |
| Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins DR Borchelt, T Ratovitski, J Van Lare, MK Lee, V Gonzales, NA Jenkins, ... Neuron 19 (4), 939-945, 1997 | 1352 | 1997 |
| Co-expression of multiple transgenes in mouse CNS: a comparison of strategies JL Jankowsky, HH Slunt, T Ratovitski, NA Jenkins, NG Copeland, ... Biomolecular engineering 17 (6), 157-165, 2001 | 930 | 2001 |
| Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin G Schilling, MW Becher, AH Sharp, HA Jinnah, K Duan, JA Kotzuk, ... Human molecular genetics 8 (3), 397-407, 1999 | 924 | 1999 |
| Protein topology of presenilin 1 A Doan, G Thinakaran, DR Borchelt, HH Slunt, T Ratovitsky, M Podlisny, ... Neuron 17 (5), 1023-1030, 1996 | 522 | 1996 |
| Induced pluripotent stem cells from patients with Huntington's disease show CAG-repeat-expansion-associated phenotypes Hd iPsc Consortium Cell stem cell 11 (2), 264-278, 2012 | 505 | 2012 |
| Evidence that levels of presenilins (PS1 and PS2) are coordinately regulated by competition for limiting cellular factors G Thinakaran, CL Harris, T Ratovitski, F Davenport, HH Slunt, DL Price, ... Journal of Biological Chemistry 272 (45), 28415-28422, 1997 | 434 | 1997 |
| A vector for expressing foreign genes in the brains and hearts of transgenic mice DR Borchelt, J Davis, M Fischer, MK Lee, HH Slunt, T Ratovitsky, ... Genetic analysis: biomolecular engineering 13 (6), 159-163, 1996 | 409 | 1996 |
| Endoproteolytic processing and stabilization of wild-type and mutant presenilin T Ratovitski, HH Slunt, G Thinakaran, DL Price, SS Sisodia, DR Borchelt Journal of Biological Chemistry 272 (39), 24536-24541, 1997 | 294 | 1997 |
| Expression of myostatin pro domain results in muscular transgenic mice J Yang, T Ratovitski, JP Brady, MB Solomon, KD Wells, RJ Wall Molecular Reproduction and Development: Incorporating Gamete Research 60 (3 …, 2001 | 233 | 2001 |
| Variation in the biochemical/biophysical properties of mutant superoxide dismutase 1 enzymes and the rate of disease progression in familial amyotrophic lateral sclerosis kindreds T Ratovitski, LB Corson, J Strain, P Wong, DW Cleveland, VC Culotta, ... Human molecular genetics 8 (8), 1451-1460, 1999 | 228 | 1999 |
| Huntingtin phosphorylation sites mapped by mass spectrometry: modulation of cleavage and toxicity B Schilling, J Gafni, C Torcassi, X Cong, RH Row, MA LaFevre-Bernt, ... Journal of Biological Chemistry 281 (33), 23686-23697, 2006 | 178 | 2006 |
| Hyperaccumulation of FAD-linked presenilin 1 variants in vivo MK Lee, DR Borchelt, G Kim, G Thinakaran, HH Slunt, T Ratovitski, ... Nature medicine 3 (7), 756-760, 1997 | 175 | 1997 |
| Mutant huntingtin N-terminal fragments of specific size mediate aggregation and toxicity in neuronal cells T Ratovitski, M Gucek, H Jiang, E Chighladze, E Waldron, J D'Ambola, ... Journal of Biological Chemistry 284 (16), 10855-10867, 2009 | 168 | 2009 |
| Huntingtin protein interactions altered by polyglutamine expansion as determined by quantitative proteomic analysis T Ratovitski, E Chighladze, N Arbez, T Boronina, S Herbrich, RN Cole, ... Cell Cycle 11 (10), 2006-2021, 2012 | 158 | 2012 |
| Dopamine-induced apoptosis in human neuronal cells: inhibition by nucleic acids antisense to the dopamine transporter R Simantov, E Blinder, T Ratovitski, M Tauber, M Gabbay, S Porat Neuroscience 74 (1), 39-50, 1996 | 158 | 1996 |
| Characterization and identification of the inhibitory domain of GDF-8 propeptide MS Jiang, L Liang, S Wang, T Ratovitski, J Holmstrom, C Barker, R Stotish Biochemical and biophysical research communications 315 (3), 525-531, 2004 | 151 | 2004 |
| Identification of novel potentially toxic oligomers formed in vitro from mammalian-derived expanded huntingtin exon-1 protein LG Nucifora, KA Burke, X Feng, N Arbez, S Zhu, J Miller, G Yang, ... Journal of Biological Chemistry 287 (19), 16017-16028, 2012 | 137 | 2012 |
| N-terminal proteolysis of full-length mutant huntingtin in an inducible PC12 cell model of Huntington’s disease T Ratovitski, M Nakamura, J D'Ambola, E Chighladze, Y Liang, W Wang, ... Cell Cycle 6 (23), 2970-2981, 2007 | 84 | 2007 |
