| Role of NF-E2 related factor 2 (Nrf2) on chemotherapy resistance in acute myeloid leukemia (AML) and the effect of pharmacological inhibition of Nrf2 S Karathedath, BM Rajamani, SM Musheer Aalam, A Abraham, ... PloS one 12 (5), e0177227, 2017 | 79 | 2017 |
| SIRT1 regulates metabolism and leukemogenic potential in CML stem cells A Abraham, S Qiu, BK Chacko, H Li, A Paterson, J He, P Agarwal, M Shah, ... The Journal of clinical investigation 129 (7), 2685-2701, 2019 | 71 | 2019 |
| Cytidine deaminase genetic variants influence RNA expression and cytarabine cytotoxicity in acute myeloid leukemia A Abraham, S Varatharajan, S Abbas, W Zhang, RV Shaji, R Ahmed, ... Pharmacogenomics 13 (3), 269-282, 2012 | 56 | 2012 |
| RNA expression of genes involved in cytarabine metabolism and transport predicts cytarabine response in acute myeloid leukemia A Abraham, S Varatharajan, S Karathedath, C Philip, KM Lakshmi, ... Pharmacogenomics 16 (8), 877-890, 2015 | 51 | 2015 |
| Catalytically inactive Dnmt3b rescues mouse embryonic development by accessory and repressive functions P Nowialis, K Lopusna, J Opavska, SL Haney, A Abraham, P Sheng, ... Nature communications 10 (1), 4374, 2019 | 39 | 2019 |
| Carbonyl reductase 1 expression influences daunorubicin metabolism in acute myeloid leukemia S Varatharajan, A Abraham, W Zhang, RV Shaji, R Ahmed, A Abraham, ... European journal of clinical pharmacology 68, 1577-1586, 2012 | 36 | 2012 |
| ATP-binding casette transporter expression in acute myeloid leukemia: association with in vitro cytotoxicity and prognostic markers S Varatharajan, A Abraham, S Karathedath, S Ganesan, KM Lakshmi, ... Pharmacogenomics 18 (3), 235-244, 2017 | 34 | 2017 |
| Population pharmacokinetics of Daunorubicin in adult patients with acute myeloid leukemia S Varatharajan, JC Panetta, A Abraham, S Karathedath, E Mohanan, ... Cancer chemotherapy and pharmacology 78, 1051-1058, 2016 | 24 | 2016 |
| Effect of cytosine arabinoside metabolizing enzyme expression on drug toxicity in acute myeloid leukemia A Abraham, AJ Devasia, S Varatharajan, S Karathedath, ... Annals of hematology 94, 883-885, 2015 | 16 | 2015 |
| Hedgehog signaling in myeloid malignancies A Abraham, W Matsui Cancers 13 (19), 4888, 2021 | 15 | 2021 |
| Dnmt3b catalytic activity is critical for its tumour suppressor function in lymphomagenesis and is associated with c-Met oncogenic signalling K Lopusna, P Nowialis, J Opavska, A Abraham, A Riva, R Opavsky EBioMedicine 63, 103191, 2021 | 11 | 2021 |
| Decreases in different Dnmt3b activities drive distinct development of hematologic malignancies in mice K Lopusna, P Nowialis, J Opavska, A Abraham, A Riva, SL Haney, ... Journal of Biological Chemistry, 100285, 2021 | 9 | 2021 |
| ABCB6 RNA expression in leukemias—expression is low in acute promyelocytic leukemia and FLT3-ITD-positive acute myeloid leukemia A Abraham, S Karathedath, S Varatharajan, P Markose, E Chendamarai, ... Annals of hematology 93, 509-512, 2014 | 8 | 2014 |
| Role of enhanced autophagy in resistance of FLT3-ITD AML stem cells to FLT3 TKI treatment S Qiu, AJ Paterson, A Abraham, J He, M Shah, P Agarwal, AK Mullen, H Li, ... Blood 132, 1358, 2018 | 6 | 2018 |
| Low c-Kit expression identifies primitive, therapy-resistant CML stem cells M Shah, H Kumar, S Qiu, H Li, M Harris, J He, A Abraham, DK Crossman, ... JCI insight 8 (1), 2023 | 5 | 2023 |
| Population pharmacokinetics of fludarabine and treosulfan in patients with thalassemia undergoing hematopoietic stem cell transplantation EP Mohanan, JC Panetta, SSB Royan, A Abraham, ES Edison, ... Blood 126 (23), 3120, 2015 | 4 | 2015 |
| Toward a systems-level probing of tumor clonality EI Grody, A Abraham, V Shukla, Y Goyal Iscience 26 (5), 2023 | 3 | 2023 |
| SIRT1 mediates enhanced mitochondrial oxidative phosphorylation in chronic myelogenous leukemia stem cells A Abraham, S Qiu, BK Chacko, H Li, AJ Paterson, J He, P Agarwal, ... Blood 132, 932, 2018 | 3 | 2018 |
| Expression of Ara-C metabolizing enzymes mediates in vitro sensitivity to Ara-C in primary AML cells from patients with denovo AML A Abraham, S Varatharajan, A kumar Jayavelu, SR Velayudhan, ... Blood 118 (21), 3481, 2011 | 3 | 2011 |
| Role of Autophagy in Resistance of FLT3-ITD AML Stem Cells to FLT3 TKI Treatment S Qiu, C Yan, AJ Paterson, H Li, N Anderson, A Abraham, J He, M Shah, ... Blood 134, 2548, 2019 | 2 | 2019 |
Poonkuzhali BalasubramanianProfessor, Department of Haematology, Christian Medical College, Vellore-632004, IndiaVerified email at cmcvellore.ac.in