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MARIANA G. FRONZA
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Antidepressant-like effect of a new selenium-containing compound is accompanied by a reduction of neuroinflammation and oxidative stress in lipopolysaccharide-challenged mice
AM Casaril, M Domingues, M Fronza, B Vieira, K Begnini, EJ Lenardão, ...
Journal of Psychopharmacology 31 (9), 1263-1273, 2017
672017
Involvement of monoaminergic system in the antidepressant-like effect of (octylseleno)-xylofuranoside in the mouse tail suspension test
LMP Brod, MG Fronza, JP Vargas, DS Luedtke, C Luchese, EA Wilhelm, ...
Progress in Neuro-Psychopharmacology and Biological Psychiatry 65, 201-207, 2016
522016
Ultrasound-promoted copper-catalyzed synthesis of bis-arylselanyl chrysin derivatives with boosted antioxidant and anticancer activities
SF Fonseca, NB Padilha, S Thurow, JA Roehrs, L Savegnago, ...
Ultrasonics Sonochemistry 39, 827-836, 2017
482017
α-(phenylselanyl) acetophenone mitigates reserpine-induced pain–depression dyad: Behavioral, biochemical and molecular docking evidences
FSS Sousa, PT Birmann, R Baldinotti, MG Fronza, R Balaguez, D Alves, ...
Brain Research Bulletin 142, 129-137, 2018
422018
Rational design, cognition and neuropathology evaluation of QTC-4-MeOBnE in a streptozotocin-induced mouse model of sporadic Alzheimer’s disease
MG Fronza, R Baldinotti, MC Martins, B Goldani, BT Dalberto, FS Kremer, ...
Scientific Reports 9 (1), 7276, 2019
352019
Lipopolysaccharide-induced depressive-like, anxiogenic-like and hyperalgesic behavior is attenuated by acute administration of α-(phenylselanyl) acetophenone in mice
FSS Sousa, PT Birmann, SR Bampi, MG Fronza, R Balaguez, D Alves, ...
Neuropharmacology 146, 128-137, 2019
352019
Phenylselanyl-1 H-1, 2, 3-triazole-4-carbonitriles: Synthesis, antioxidant properties and use as precursors to highly functionalized tetrazoles
L Savegnago, M do Sacramento, LMP Brod, MG Fronza, N Seus, ...
RSC advances 6 (10), 8021-8031, 2016
342016
Beneficial effects of QTC-4-MeOBnE in an LPS-induced mouse model of depression and cognitive impairments: The role of blood-brain barrier permeability, NF-κB signaling, and …
MG Fronza, R Baldinotti, J Fetter, SG Rosa, M Sacramento, CW Nogueira, ...
Brain, behavior, and immunity 99, 177-191, 2022
262022
The selenocompound 1-methyl-3-(phenylselanyl)-1H-indole attenuates depression-like behavior, oxidative stress, and neuroinflammation in streptozotocin-treated mice
SR Bampi, AM Casaril, MG Fronza, M Domingues, B Vieira, KR Begnini, ...
Brain research bulletin 161, 158-165, 2020
262020
Chrysin restores memory deficit in hypothyroidism mice: Behavioral, neurochemical and computational approaches involving the neurotrophinergic system
VC Bortolotto, SM Araujo, FC Pinheiro, MR Poetini, LB Meichtry, ...
Journal of Psychiatric Research 144, 225-233, 2021
212021
The neurobiology and therapeutic potential of multi-targeting β-secretase, glycogen synthase kinase 3β and acetylcholinesterase in Alzheimer’s disease
MG Fronza, D Alves, D Praticò, L Savegnago
Ageing research reviews, 102033, 2023
202023
Effect of QTC-4-MeOBnE treatment on memory, neurodegeneration, and neurogenesis in a streptozotocin-induced mouse model of Alzheimer’s disease
MG Fronza, R Baldinotti, M Sacramento, J Gutierres, FB Carvalho, ...
ACS chemical neuroscience 12 (1), 109-122, 2020
202020
Apoptosis induction by 7-chloroquinoline-1, 2, 3-triazoyl carboxamides in triple negative breast cancer cells
KR Begnini, WR Duarte, LP da Silva, JH Buss, BS Goldani, M Fronza, ...
Biomedicine & Pharmacotherapy 91, 510-516, 2017
192017
Effect of a purine derivative containing selenium to improve memory decline and anxiety through modulation of the cholinergic system and Na+/K+-ATPase in an …
MP Pinz, AG Vogt, K da Costa Rodrigues, AS Dos Reis, LFB Duarte, ...
Metabolic brain disease 36, 871-888, 2021
182021
Modulation of PKA, PKC, CAMKII, ERK 1/2 pathways is involved in the acute antidepressant-like effect of (octylseleno)-xylofuranoside (OSX) in mice
LM Pinto Brod, MG Fronza, JP Vargas, DS Lüdtke, CA Brüning, ...
Psychopharmacology 234, 717-725, 2017
172017
7-Chloroquinoline-1, 2, 3-triazoyl carboxamides induce cell cycle arrest and apoptosis in human bladder carcinoma cells
MS Sonego, NV Segatto, L Dame, M Fronza, CB Gomes, TL Oliveira, ...
Investigational New Drugs 38, 1020-1030, 2020
162020
Synthesis, photophysics and biomolecule interactive studies of new hybrid benzo-2, 1, 3-thiadiazoles
JSS Neto, R Krüger, RA Balaguez, MG Fronza, TV Acunha, RS Oliboni, ...
New Journal of Chemistry 44 (7), 2768-2780, 2020
142020
QTC-4-MeOBnE rescues scopolamine-induced memory deficits in mice by targeting oxidative stress, neuronal plasticity, and apoptosis
MG Fronza, R Baldinotti, J Fetter, M Sacramento, FSS Sousa, FK Seixas, ...
ACS Chemical Neuroscience 11 (9), 1259-1269, 2020
132020
A new arylsulfanyl-benzo-2, 1, 3-thiadiazoles derivative produces an anti-amnesic effect in mice by modulating acetylcholinesterase activity
K da Costa Rodrigues, RL de Oliveira, J da Silva Chaves, VME da Rocha, ...
Chemico-Biological Interactions 351, 109736, 2022
112022
Bis-Triazolylchalcogenium-Functionalized Benzothiadiazole Derivatives as Light-up Sensors for DNA and BSA
R Krüger, A Larroza, MG Fronza, I Tisoco, L Savegnago, JS Reis, ...
The Journal of Organic Chemistry 86 (24), 17866-17883, 2021
112021
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