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Brian Leibowitz
Brian Leibowitz
Assistant Professor of Radiation Oncology, University of Pittsburgh School of Medicine
Verified email at upmc.edu
Title
Cited by
Cited by
Year
Mitochondrial signaling in cell death via the Bcl-2 family
B Leibowitz, J Yu
Cancer biology & therapy 9 (6), 417-422, 2010
3022010
Growth factors protect intestinal stem cells from radiation-induced apoptosis by suppressing PUMA through the PI3K/AKT/p53 axis
W Qiu, B Leibowitz, L Zhang, J Yu
Oncogene 29 (11), 1622-1632, 2010
1692010
Uncoupling p53 functions in radiation-induced intestinal damage via PUMA and p21
BJ Leibowitz, W Qiu, H Liu, T Cheng, L Zhang, J Yu
Molecular cancer research 9 (5), 616-625, 2011
1422011
Chemoprevention by nonsteroidal anti-inflammatory drugs eliminates oncogenic intestinal stem cells via SMAC-dependent apoptosis
W Qiu, X Wang, B Leibowitz, H Liu, N Barker, H Okada, N Oue, W Yasui, ...
Proceedings of the National Academy of Sciences 107 (46), 20027-20032, 2010
1162010
Inhibition of CDK4/6 protects against radiation-induced intestinal injury in mice
L Wei, BJ Leibowitz, X Wang, M Epperly, J Greenberger, L Zhang, J Yu
The Journal of clinical investigation 126 (11), 4076-4087, 2016
1082016
Immunogenic cell death in colon cancer prevention and therapy
H Ruan, BJ Leibowitz, L Zhang, J Yu
Molecular carcinogenesis 59 (7), 783-793, 2020
1042020
PUMA–mediated apoptosis drives chemical hepatocarcinogenesis in mice
W Qiu, X Wang, B Leibowitz, W Yang, L Zhang, J Yu
Hepatology 54 (4), 1249-1258, 2011
952011
Pharmacologically blocking p53-dependent apoptosis protects intestinal stem cells and mice from radiation
X Wang, L Wei, JM Cramer, BJ Leibowitz, C Judge, M Epperly, ...
Scientific reports 5 (1), 8566, 2015
862015
Ionizing irradiation induces acute haematopoietic syndrome and gastrointestinal syndrome independently in mice
BJ Leibowitz, L Wei, L Zhang, X Ping, M Epperly, J Greenberger, T Cheng, ...
Nature communications 5 (1), 3494, 2014
792014
Early prediction of cancer progression by depth-resolved nanoscale mapping of nuclear architecture from unstained tissue specimens
S Uttam, HV Pham, J LaFace, B Leibowitz, J Yu, RE Brand, DJ Hartman, ...
Cancer research 75 (22), 4718-4727, 2015
682015
Loss of caspase-3 sensitizes colon cancer cells to genotoxic stress via RIP1-dependent necrosis
MF Brown, BJ Leibowitz, D Chen, K He, F Zou, RW Sobol, D Beer-Stolz, ...
Cell death & disease 6 (4), e1729-e1729, 2015
552015
Targeting p53-dependent stem cell loss for intestinal chemoprotection
BJ Leibowitz, L Yang, L Wei, ME Buchanan, M Rachid, RA Parise, ...
Science translational medicine 10 (427), eaam7610, 2018
512018
IGF-I differentially regulates IGF-binding protein expression in primary mammary fibroblasts and epithelial cells
JM Fleming, BJ Leibowitz, DE Kerr, WS Cohick
Journal of endocrinology 186 (1), 165-178, 2005
502005
Endogenous IGFBP‐3 is required for both growth factor‐stimulated cell proliferation and cytokine‐induced apoptosis in mammary epithelial cells
BJ Leibowitz, WS Cohick
Journal of cellular physiology 220 (1), 182-188, 2009
452009
BID mediates selective killing of APC-deficient cells in intestinal tumor suppression by nonsteroidal antiinflammatory drugs
B Leibowitz, W Qiu, ME Buchanan, F Zou, P Vernon, MP Moyer, XM Yin, ...
Proceedings of the National Academy of Sciences 111 (46), 16520-16525, 2014
372014
Interferon β drives intestinal regeneration after radiation
BJ Leibowitz, G Zhao, L Wei, H Ruan, M Epperly, L Chen, X Lu, ...
Science Advances 7 (41), eabi5253, 2021
322021
Non-steroidal anti-inflammatory drugs induce immunogenic cell death in suppressing colorectal tumorigenesis
R Fletcher, J Tong, D Risnik, BJ Leibowitz, YJ Wang, ...
Oncogene 40 (11), 2035-2050, 2021
312021
eIF4E S209 phosphorylation licenses myc-and stress-driven oncogenesis
H Ruan, X Li, X Xu, BJ Leibowitz, J Tong, L Chen, L Ao, W Xing, J Luo, ...
Elife 9, e60151, 2020
292020
Second-generation probiotics producing IL-22 increase survival of mice after total body irradiation
X Zhang, R Fisher, W Hou, D Shields, MW Epperly, H Wang, L Wei, ...
in vivo 34 (1), 39-50, 2020
292020
Intestinal Radiation Protection and Mitigation by Second-Generation Probiotic Lactobacillus-reuteri Engineered to Deliver Interleukin-22
A Espinal, MW Epperly, A Mukherjee, R Fisher, D Shields, H Wang, ...
International journal of molecular sciences 23 (10), 5616, 2022
212022
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