Mitochondrial signaling in cell death via the Bcl-2 family B Leibowitz, J Yu Cancer biology & therapy 9 (6), 417-422, 2010 | 302 | 2010 |
Growth factors protect intestinal stem cells from radiation-induced apoptosis by suppressing PUMA through the PI3K/AKT/p53 axis W Qiu, B Leibowitz, L Zhang, J Yu Oncogene 29 (11), 1622-1632, 2010 | 169 | 2010 |
Uncoupling p53 functions in radiation-induced intestinal damage via PUMA and p21 BJ Leibowitz, W Qiu, H Liu, T Cheng, L Zhang, J Yu Molecular cancer research 9 (5), 616-625, 2011 | 142 | 2011 |
Chemoprevention by nonsteroidal anti-inflammatory drugs eliminates oncogenic intestinal stem cells via SMAC-dependent apoptosis W Qiu, X Wang, B Leibowitz, H Liu, N Barker, H Okada, N Oue, W Yasui, ... Proceedings of the National Academy of Sciences 107 (46), 20027-20032, 2010 | 116 | 2010 |
Inhibition of CDK4/6 protects against radiation-induced intestinal injury in mice L Wei, BJ Leibowitz, X Wang, M Epperly, J Greenberger, L Zhang, J Yu The Journal of clinical investigation 126 (11), 4076-4087, 2016 | 108 | 2016 |
Immunogenic cell death in colon cancer prevention and therapy H Ruan, BJ Leibowitz, L Zhang, J Yu Molecular carcinogenesis 59 (7), 783-793, 2020 | 104 | 2020 |
PUMA–mediated apoptosis drives chemical hepatocarcinogenesis in mice W Qiu, X Wang, B Leibowitz, W Yang, L Zhang, J Yu Hepatology 54 (4), 1249-1258, 2011 | 95 | 2011 |
Pharmacologically blocking p53-dependent apoptosis protects intestinal stem cells and mice from radiation X Wang, L Wei, JM Cramer, BJ Leibowitz, C Judge, M Epperly, ... Scientific reports 5 (1), 8566, 2015 | 86 | 2015 |
Ionizing irradiation induces acute haematopoietic syndrome and gastrointestinal syndrome independently in mice BJ Leibowitz, L Wei, L Zhang, X Ping, M Epperly, J Greenberger, T Cheng, ... Nature communications 5 (1), 3494, 2014 | 79 | 2014 |
Early prediction of cancer progression by depth-resolved nanoscale mapping of nuclear architecture from unstained tissue specimens S Uttam, HV Pham, J LaFace, B Leibowitz, J Yu, RE Brand, DJ Hartman, ... Cancer research 75 (22), 4718-4727, 2015 | 68 | 2015 |
Loss of caspase-3 sensitizes colon cancer cells to genotoxic stress via RIP1-dependent necrosis MF Brown, BJ Leibowitz, D Chen, K He, F Zou, RW Sobol, D Beer-Stolz, ... Cell death & disease 6 (4), e1729-e1729, 2015 | 55 | 2015 |
Targeting p53-dependent stem cell loss for intestinal chemoprotection BJ Leibowitz, L Yang, L Wei, ME Buchanan, M Rachid, RA Parise, ... Science translational medicine 10 (427), eaam7610, 2018 | 51 | 2018 |
IGF-I differentially regulates IGF-binding protein expression in primary mammary fibroblasts and epithelial cells JM Fleming, BJ Leibowitz, DE Kerr, WS Cohick Journal of endocrinology 186 (1), 165-178, 2005 | 50 | 2005 |
Endogenous IGFBP‐3 is required for both growth factor‐stimulated cell proliferation and cytokine‐induced apoptosis in mammary epithelial cells BJ Leibowitz, WS Cohick Journal of cellular physiology 220 (1), 182-188, 2009 | 45 | 2009 |
BID mediates selective killing of APC-deficient cells in intestinal tumor suppression by nonsteroidal antiinflammatory drugs B Leibowitz, W Qiu, ME Buchanan, F Zou, P Vernon, MP Moyer, XM Yin, ... Proceedings of the National Academy of Sciences 111 (46), 16520-16525, 2014 | 37 | 2014 |
Interferon β drives intestinal regeneration after radiation BJ Leibowitz, G Zhao, L Wei, H Ruan, M Epperly, L Chen, X Lu, ... Science Advances 7 (41), eabi5253, 2021 | 32 | 2021 |
Non-steroidal anti-inflammatory drugs induce immunogenic cell death in suppressing colorectal tumorigenesis R Fletcher, J Tong, D Risnik, BJ Leibowitz, YJ Wang, ... Oncogene 40 (11), 2035-2050, 2021 | 31 | 2021 |
eIF4E S209 phosphorylation licenses myc-and stress-driven oncogenesis H Ruan, X Li, X Xu, BJ Leibowitz, J Tong, L Chen, L Ao, W Xing, J Luo, ... Elife 9, e60151, 2020 | 29 | 2020 |
Second-generation probiotics producing IL-22 increase survival of mice after total body irradiation X Zhang, R Fisher, W Hou, D Shields, MW Epperly, H Wang, L Wei, ... in vivo 34 (1), 39-50, 2020 | 29 | 2020 |
Intestinal Radiation Protection and Mitigation by Second-Generation Probiotic Lactobacillus-reuteri Engineered to Deliver Interleukin-22 A Espinal, MW Epperly, A Mukherjee, R Fisher, D Shields, H Wang, ... International journal of molecular sciences 23 (10), 5616, 2022 | 21 | 2022 |