SARS-CoV-2 infects the brain choroid plexus and disrupts the blood-CSF barrier in human brain organoids L Pellegrini, A Albecka, DL Mallery, MJ Kellner, D Paul, AP Carter, ... Cell stem cell 27 (6), 951-961. e5, 2020 | 521 | 2020 |
Human CNS barrier-forming organoids with cerebrospinal fluid production L Pellegrini, C Bonfio, J Chadwick, F Begum, M Skehel, MA Lancaster Science 369 (6500), eaaz5626, 2020 | 378 | 2020 |
Back to the tubule: microtubule dynamics in Parkinson’s disease L Pellegrini, A Wetzel, S Grannó, G Heaton, K Harvey Cellular and Molecular Life Sciences 74, 409-434, 2017 | 152 | 2017 |
Androgens increase excitatory neurogenic potential in human brain organoids I Kelava, I Chiaradia, L Pellegrini, AT Kalinka, MA Lancaster Nature 602 (7895), 112-116, 2022 | 78 | 2022 |
The Parkinson’s disease protein LRRK2 interacts with the GARP complex to promote retrograde transport to the trans-Golgi network A Beilina, L Bonet-Ponce, R Kumaran, JJ Kordich, M Ishida, A Mamais, ... Cell reports 31 (5), 2020 | 72 | 2020 |
Proteomic analysis reveals co-ordinated alterations in protein synthesis and degradation pathways in LRRK2 knockout mice L Pellegrini, DN Hauser, Y Li, A Mamais, A Beilina, R Kumaran, A Wetzel, ... Human molecular genetics 27 (18), 3257-3271, 2018 | 65 | 2018 |
Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia A Mamais, JH Kluss, L Bonet-Ponce, N Landeck, RG Langston, N Smith, ... PLoS biology 19 (12), e3001480, 2021 | 62 | 2021 |
Tissue morphology influences the temporal program of human brain organoid development I Chiaradia, I Imaz-Rosshandler, BS Nilges, J Boulanger, L Pellegrini, ... Cell stem cell 30 (10), 1351-1367. e10, 2023 | 38 | 2023 |
Sequential screening nominates the Parkinson's disease associated kinase LRRK2 as a regulator of Clathrin-mediated endocytosis GR Heaton, N Landeck, A Mamais, MA Nalls, J Nixon-Abell, R Kumaran, ... Neurobiology of disease 141, 104948, 2020 | 37 | 2020 |
Human CNS barrier-forming organoids with cerebrospinal fluid production. Science 369, eaaz5626 L Pellegrini, C Bonfio, J Chadwick, F Begum, M Skehel, MA Lancaster | 23 | 2020 |
Modeling neurodegeneration with mutant-tau organoids L Pellegrini, MA Lancaster Cell 184 (17), 4377-4379, 2021 | 13 | 2021 |
Breaking the barrier: in vitro models to study choroid plexus development L Pellegrini, MA Lancaster Current Opinion in Cell Biology 73, 41-49, 2021 | 9 | 2021 |
Pathogenic mutations in LRRK2 sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia A Mamais, N Landeck, RG Langston, L Bonet-Ponce, N Smith, A Beilina, ... | 5 | 2020 |
Correction: Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia A Mamais, JH Kluss, L Bonet-Ponce, N Landeck, RG Langston, N Smith, ... Plos Biology 20 (5), e3001621, 2022 | 3 | 2022 |
Desensitization Protocols for Anti-SARS-CoV-2 Vaccines in Patients with High Risk of Allergic Reactions MR Messina, C Crisciotti, L Pellegrini, E Nappi, F Racca, G Costanzo, ... Vaccines 11 (5), 910, 2023 | 2 | 2023 |
Male sex hormones increase excitatory neuron production in developing human neocortex I Kelava, I Chiaradia, L Pellegrini, AT Kalinka, MA Lancaster bioRxiv, 2020.10. 24.353359, 2020 | 2 | 2020 |
Mouse brain organoids model in vivo neurodevelopment and function and capture differences to human DJ Lloyd-Davies Sánchez, FW Lindhout, AJ Anderson, L Pellegrini, ... bioRxiv, 2024.12. 21.629881, 2024 | 1 | 2024 |
Choroid plexus protein turnover in human choroid plexus organoids recapitulates turnover in humans measured using stable isotope labeling kinetics (SILK) TA Giovannucci, CA Leckey, E Moncur, K Tariq, L Thorne, L Watkins, ... Alzheimer's & Dementia 19, e074240, 2023 | 1 | 2023 |
Choroid plexus organoids and methods for production thereof MA Lancaster, L Pellegrini US Patent App. 17/425,043, 2022 | 1 | 2022 |
Pathogenic mutations in leucine-rich repeat kinase 2 sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia A Mamais, N Landeck, RG Langston, L Bonet-Ponce, N Smith, A Beilina, ... bioRxiv, 2020.07. 27.219501, 2020 | 1 | 2020 |