| PARPi triggers the STING-dependent immune response and enhances the therapeutic efficacy of immune checkpoint blockade independent of BRCAness J Shen, W Zhao, Z Ju, L Wang, Y Peng, M Labrie, TA Yap, GB Mills, ... Cancer research 79 (2), 311-319, 2019 | 525 | 2019 |
| ARID1A Deficiency Impairs the DNA Damage Checkpoint and Sensitizes Cells to PARP Inhibitors S Jianfeng, P Yang, W Leizhen, Z Wei, Y Lin, L Li, K Prabodh, J Zhenlin, ... Cancer Discovery 5 (7), 1-16, 2015 | 475* | 2015 |
| ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade J Shen, Z Ju, W Zhao, L Wang, Y Peng, Z Ge, ZD Nagel, J Zou, C Wang, ... Nature medicine 24 (5), 556-562, 2018 | 473 | 2018 |
| Local generation of fumarate promotes DNA repair through inhibition of histone H3 demethylation J Yuhui, Q Xu, S Jianfeng, W Yugang, L Xinjian, L Rui, X Yan, ... Nature Cell Biology, 2015 | 201 | 2015 |
| ERK-and Akt-dependent neuroprotection by erythropoietin (EPO) against glyoxal-AGEs via modulation of Bcl-xL, Bax, and BAD J Shen, Y Wu, JY Xu, J Zhang, SH Sinclair, M Yanoff, G Xu, W Li, GT Xu Investigative ophthalmology & visual science 51 (1), 35-46, 2010 | 152 | 2010 |
| mir-30d regulates multiple genes in the autophagy pathway and impairs autophagy process in human cancer cells LZ Xiaojun Yang, Xiaomin Zhong, Janos L. Tanyi, Jianfeng Shen, Congjian Xu ... Biochemical and Biophysical Research Communications 431, 617-622, 2013 | 125 | 2013 |
| Inhibition of the ATM/Chk2 axis promotes cGAS/STING signaling in ARID1A-deficient tumors L Wang, L Yang, C Wang, W Zhao, Z Ju, W Zhang, J Shen, Y Peng, C An, ... The Journal of clinical investigation 130 (11), 5951-5966, 2020 | 88 | 2020 |
| Verteporfin inhibits PD-L1 through autophagy and the STAT1–IRF1–TRIM28 signaling axis, exerting antitumor efficacy J Liang, L Wang, C Wang, J Shen, B Su, AL Marisetty, D Fang, C Kassab, ... Cancer immunology research 8 (7), 952-965, 2020 | 85 | 2020 |
| Inhibition of DNA2 nuclease as a therapeutic strategy targeting replication stress in cancer cells S Kumar, X Peng, J Daley, L Yang, J Shen, N Nguyen, G Bae, H Niu, ... Oncogenesis 6 (4), e319-e319, 2017 | 66 | 2017 |
| SB-431542 inhibition of scar formation after filtration surgery and its potential mechanism Y Xiao, K Liu, J Shen, GT Xu, W Ye Investigative ophthalmology & visual science 50 (4), 1698-1706, 2009 | 65 | 2009 |
| Suppression of MicroRNA 200 family expression by oncogenic KRAS activation promotes cell survival and epithelial-mesenchymal transition in KRAS-driven cancer X Zhong, L Zheng, J Shen, D Zhang, M Xiong, Y Zhang, X He, JL Tanyi, ... Molecular and cellular biology 36 (21), 2742-2754, 2016 | 57 | 2016 |
| RNA-binding protein LIN28B inhibits apoptosis through regulation of the AKT2/FOXO3A/BIM axis in ovarian cancer cells X Lin, J Shen, D Peng, X He, C Xu, X Chen, JL Tanyi, K Montone, Y Fan, ... Signal transduction and targeted therapy 3 (1), 23, 2018 | 54 | 2018 |
| CXCL10 potentiates immune checkpoint blockade therapy in homologous recombination-deficient tumors Z Shi, J Shen, J Qiu, Q Zhao, K Hua, H Wang Theranostics 11 (15), 7175, 2021 | 48 | 2021 |
| EPO reduces reactive gliosis and stimulates neurotrophin expression in Muller cells WL Liu-Mei Hu, Yan Luo, Jingfa Zhang, Xia Lei, Jianfeng Shen, Yalan Wu, Mei ... Frontiers in Bioscience 3, 1541-1555, 2011 | 48* | 2011 |
| EPO attenuates inflammatory cytokines by Muller cells in diabetic retinopathy. X Lei, J Zhang, J Shen, LM Hu, Y Wu, L Mou, G Xu, W Li, GT Xu Frontiers in bioscience (Elite edition) 3 (1), 201-211, 2011 | 43 | 2011 |
| ARID1A deficiency impairs the DNA damage checkpoint and sensitizes cells to PARP inhibitors. Cancer Discov. 2015; 5: 752–767. doi: 10.1158/2159-8290 J Shen, Y Peng, L Wei, W Zhang, L Yang, L Lan, P Kapoor, Z Ju, Q Mo, ... CD-14-0849.[Europe PMC free article][Abstract][CrossRef][Academic Search], 0 | 42 | |
| Systems biology approach reveals a link between mTORC1 and G2/M DNA damage checkpoint recovery HJ Hsieh, W Zhang, SH Lin, WH Yang, JZ Wang, J Shen, Y Zhang, Y Lu, ... Nature communications 9 (1), 3982, 2018 | 40 | 2018 |
| PARP mediated DNA damage response, genomic stability and immune responses C Zong, T Zhu, J He, R Huang, R Jia, J Shen International Journal of Cancer 150 (11), 1745-1759, 2022 | 37 | 2022 |
| Emerging role of SWI/SNF complex deficiency as a target of immune checkpoint blockade in human cancers M Zhou, J Yuan, Y Deng, X Fan, J Shen Oncogenesis 10 (1), 3, 2021 | 37 | 2021 |
| Metal ions and nanometallic materials in antitumor immunity: Function, application, and perspective F Shen, Y Fang, Y Wu, M Zhou, J Shen, X Fan Journal of Nanobiotechnology 21 (1), 20, 2023 | 36 | 2023 |
Gordon MillsOregon Health & Science UniversityVerified email at ohsu.edu
