G-quadruplex, Friend or Foe: The Role of the G-quartet in Anticancer Strategies J Carvalho, JL Mergny, GF Salgado, JA Queiroz, C Cruz Trends in molecular medicine 26 (9), 848-861, 2020 | 240 | 2020 |
Aptamer-based targeted delivery of a G-quadruplex ligand in cervical cancer cells J Carvalho, A Paiva, MP Cabral Campello, A Paulo, JL Mergny, ... Scientific reports 9 (1), 7945, 2019 | 107 | 2019 |
G-quadruplexes and their ligands: Biophysical methods to unravel G-quadruplex/ligand interactions T Santos, GF Salgado, EJ Cabrita, C Cruz Pharmaceuticals 14 (8), 769, 2021 | 100 | 2021 |
Circular dichroism of G-Quadruplex: A laboratory experiment for the study of topology and ligand binding J Carvalho, JA Queiroz, C Cruz Journal of Chemical Education 94 (10), 1547-1551, 2017 | 90 | 2017 |
Amino acids–nucleotides biomolecular recognition: from biological occurrence to affinity chromatography F Sousa, C Cruz, JA Queiroz Journal of Molecular Recognition 23 (6), 505-518, 2010 | 59 | 2010 |
Fluorescent light-up acridine orange derivatives bind and stabilize KRAS-22RT G-quadruplex J Carvalho, E Pereira, J Marquevielle, MPC Campello, JL Mergny, ... Biochimie 144, 144-152, 2018 | 53 | 2018 |
Multicharged phthalocyanines as selective ligands for G-quadruplex DNA structures CIV Ramos, SP Almeida, LMO Lourenço, PMR Pereira, R Fernandes, ... Molecules 24 (4), 733, 2019 | 48 | 2019 |
In vitro effect of free and complexed indium(III) against Mycobacterium tuberculosis S David, V Barros, C Cruz, R Delgado FEMS microbiology letters 251 (1), 119-124, 2005 | 45 | 2005 |
Aptamer-guided acridine derivatives for cervical cancer J Carvalho, J Lopes-Nunes, AC Lopes, MPC Campello, A Paulo, ... Organic & Biomolecular Chemistry 17 (11), 2992-3002, 2019 | 43 | 2019 |
AS1411 derivatives as carriers of G-quadruplex ligands for cervical cancer cells J Figueiredo, J Lopes-Nunes, J Carvalho, F Antunes, M Ribeiro, ... International Journal of Pharmaceutics 568, 118511, 2019 | 39 | 2019 |
Phthalocyanines for G-quadruplex aptamers binding J Lopes-Nunes, J Carvalho, J Figueiredo, CIV Ramos, LMO Lourenco, ... Bioorganic chemistry 100, 103920, 2020 | 37 | 2020 |
G-quadruplex ligands in cancer therapy: Progress, challenges, and clinical perspectives J Figueiredo, JL Mergny, C Cruz Life Sciences, 122481, 2024 | 36 | 2024 |
Metal-based G-quadruplex binders for cancer theranostics E Palma, J Carvalho, C Cruz, A Paulo Pharmaceuticals 14 (7), 605, 2021 | 34 | 2021 |
Phenanthroline polyazamacrocycles as G-quadruplex DNA binders J Carvalho, T Quintela, NM Gueddouda, A Bourdoncle, JL Mergny, ... Organic & Biomolecular Chemistry 16 (15), 2776-2786, 2018 | 33 | 2018 |
Study of the interaction between indole-based compounds and biologically relevant G-quadruplexes J Carvalho, P Nottelet, JL Mergny, JA Queiroz, GF Salgado, C Cruz Biochimie 135, 186-195, 2017 | 33 | 2017 |
Aptamer-functionalized gold nanoparticles for drug delivery to gynecological carcinoma cells J Lopes-Nunes, AS Agonia, T Rosado, E Gallardo, ... Cancers 13 (16), 4038, 2021 | 32 | 2021 |
RNA G-quadruplex as supramolecular carrier for cancer-selective delivery T Santos, P Pereira, MPC Campello, A Paulo, JA Queiroz, E Cabrita, ... European Journal of Pharmaceutics and Biopharmaceutics 142, 473-479, 2019 | 32 | 2019 |
G-Quadruplex-based drug delivery systems for cancer therapy J Lopes-Nunes, PA Oliveira, C Cruz Pharmaceuticals 14 (7), 671, 2021 | 31 | 2021 |
Nucleolin: a binding partner of G-quadruplex structures T Santos, GF Salgado, EJ Cabrita, C Cruz Trends in cell biology 32 (7), 561-564, 2022 | 30 | 2022 |
Cell proliferation effects of calix [4] arene derivatives D Santos, J Medeiros-Silva, S Cegonho, E Alves, F Ramilo-Gomes, ... Tetrahedron 71 (40), 7593-7599, 2015 | 29 | 2015 |