| Characterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia M Toots, JJ Yoon, RM Cox, M Hart, ZM Sticher, N Makhsous, R Plesker, ... Science translational medicine 11 (515), eaax5866, 2019 | 326 | 2019 |
| Orally efficacious broad-spectrum ribonucleoside analog inhibitor of influenza and respiratory syncytial viruses JJ Yoon, M Toots, S Lee, ME Lee, B Ludeke, JM Luczo, K Ganti, RM Cox, ... Antimicrobial agents and chemotherapy 62 (8), 10.1128/aac. 00766-18, 2018 | 236 | 2018 |
| Engagement of the ATR-dependent DNA damage response at the human papillomavirus 18 replication centers during the initial amplification T Reinson, M Toots, M Kadaja, R Pipitch, M Allik, E Ustav, M Ustav Journal of virology 87 (2), 951-964, 2013 | 160 | 2013 |
| Quantitative efficacy paradigms of the influenza clinical drug candidate EIDD-2801 in the ferret model M Toots, JJ Yoon, M Hart, MG Natchus, GR Painter, RK Plemper Translational Research 218, 16-28, 2020 | 132 | 2020 |
| 4′-Fluorouridine is an oral antiviral that blocks respiratory syncytial virus and SARS-CoV-2 replication J Sourimant, CM Lieber, M Aggarwal, RM Cox, JD Wolf, JJ Yoon, M Toots, ... Science 375 (6577), 161-167, 2022 | 82 | 2022 |
| Next-generation direct-acting influenza therapeutics M Toots, RK Plemper Translational Research 220, 33-42, 2020 | 77 | 2020 |
| The cell cycle timing of human papillomavirus DNA replication T Reinson, L Henno, M Toots, M Ustav Jr, M Ustav PLoS One 10 (7), e0131675, 2015 | 71 | 2015 |
| The transcription map of human papillomavirus type 18 during genome replication in U2OS cells M Toots, A Männik, G Kivi, M Ustav Jr, E Ustav, M Ustav PloS one 9 (12), e116151, 2014 | 39 | 2014 |
| Identification of several high-risk HPV inhibitors and drug targets with a novel high-throughput screening assay M Toots, M Ustav Jr, A Männik, K Mumm, K Tämm, T Tamm, E Ustav, ... PLoS pathogens 13 (2), e1006168, 2017 | 32 | 2017 |
| Orally efficacious broad-spectrum allosteric inhibitor of paramyxovirus polymerase RM Cox, J Sourimant, M Toots, JJ Yoon, S Ikegame, M Govindarajan, ... Nature microbiology 5 (10), 1232-1246, 2020 | 25 | 2020 |
| Development of an allosteric inhibitor class blocking RNA elongation by the respiratory syncytial virus polymerase complex RM Cox, M Toots, JJ Yoon, J Sourimant, B Ludeke, R Fearns, E Bourque, ... Journal of Biological Chemistry 293 (43), 16761-16777, 2018 | 25 | 2018 |
| Characterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia. Sci Transl Med 11: eaax5866 M Toots, JJ Yoon, RM Cox, M Hart, ZM Sticher, N Makhsous, R Plesker, ... | 24 | 2019 |
| Orally efficacious lead of the AVG inhibitor series targeting a dynamic interface in the respiratory syncytial virus polymerase J Sourimant, CM Lieber, JJ Yoon, M Toots, M Govindarajan, V Udumula, ... Science Advances 8 (25), eabo2236, 2022 | 17 | 2022 |
| 4’-Fluorouridine mitigates lethal infection with pandemic human and highly pathogenic avian influenza viruses CM Lieber, M Aggarwal, JJ Yoon, RM Cox, HJ Kang, J Sourimant, ... Plos Pathogens 19 (4), e1011342, 2023 | 12 | 2023 |
| TM9SF4 expression in tumor tissues: a novel diagnostic biomarker for gastrointestinal tumors P Guazzi, D Zocco, S Isajevs, N Zarovni, L Bianciardi, M Toots, A Sivins, ... Translational Cancer Research 9 (11), 6652, 2020 | 7 | 2020 |
| 4’-Fluorouridine is a broad-spectrum orally efficacious antiviral blocking respiratory syncytial virus and SARS-CoV-2 replication J Sourimant, CM Lieber, M Aggarwal, RM Cox, JD Wolf, JJ Yoon, M Toots, ... bioRxiv, 2021.05. 19.444875, 2021 | 4 | 2021 |
| Platform for developing stable mammalian cell lines K Õunap, E Tombak, M Toots, M Jakobson, M Ustav Jr, K Murumets, ... US Patent App. 18/314,979, 2023 | | 2023 |
| Platform for developing stable mammalian cell lines K Õunap, E Tombak, M Toots, M Jakobson, M Ustav Jr, K Murumets, ... US Patent 11,685,936, 2023 | | 2023 |
| Human papilloma virus replication inhibitors M Ustav Sr, E Ustav, A Männik, M Toots, A Tover US Patent 11,000,529, 2021 | | 2021 |
| Assay system to identify HPV replication inhibitors in HT-screen M Ustav, E Ustav, A Männik, M Toots, M Ustav Jr, A Tover US Patent 10,954,545, 2021 | | 2021 |
