Targeted genome editing across species using ZFNs and TALENs AJ Wood, TW Lo, B Zeitler, CS Pickle, EJ Ralston, AH Lee, R Amora, ... Science 333 (6040), 307-307, 2011 | 997 | 2011 |
Rapid and efficient clathrin-mediated endocytosis revealed in genome-edited mammalian cells JB Doyon, B Zeitler, J Cheng, AT Cheng, JM Cherone, Y Santiago, ... Nature cell biology 13 (3), 331-337, 2011 | 278 | 2011 |
Site-specific genome editing in Plasmodium falciparum using engineered zinc-finger nucleases J Straimer, MCS Lee, AH Lee, B Zeitler, AE Williams, JR Pearl, L Zhang, ... Nature methods 9 (10), 993-998, 2012 | 210 | 2012 |
Efficient targeted gene disruption in the soma and germ line of the frog Xenopus tropicalis using engineered zinc-finger nucleases JJ Young, JM Cherone, Y Doyon, I Ankoudinova, FM Faraji, AH Lee, ... Proceedings of the National Academy of Sciences 108 (17), 7052-7057, 2011 | 160 | 2011 |
DNA repair mechanisms and their biological roles in the malaria parasite Plasmodium falciparum AH Lee, LS Symington, DA Fidock Microbiology and Molecular Biology Reviews 78 (3), 469-486, 2014 | 146 | 2014 |
Mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, enlarge the parasite’s food vacuole and alter drug sensitivities S Pulcini, HM Staines, AH Lee, SH Shafik, G Bouyer, CM Moore, ... Scientific reports 5 (1), 14552, 2015 | 101 | 2015 |
Dynamic loading of human engineered heart tissue enhances contractile function and drives a desmosome-linked disease phenotype JM Bliley, MCSC Vermeer, RM Duffy, I Batalov, D Kramer, JW Tashman, ... Science Translational Medicine 13 (603), eabd1817, 2021 | 90 | 2021 |
The skin cancer chemotherapeutic agent ingenol-3-angelate (PEP005) is a substrate for the epidermal multidrug transporter (ABCB1) and targets tumor vasculature L Li, S Shukla, A Lee, SH Garfield, DJ Maloney, SV Ambudkar, SH Yuspa Cancer research 70 (11), 4509-4519, 2010 | 88 | 2010 |
Compositional characterization of different industrial white and red grape pomaces in Virginia and the potential valorization of the major components Q Jin, J O’Hair, AC Stewart, SF O’Keefe, AP Neilson, YT Kim, M McGuire, ... Foods 8 (12), 667, 2019 | 79 | 2019 |
Evidence of a Mild Mutator Phenotype in Cambodian Plasmodium falciparum Malaria Parasites AH Lee, DA Fidock PloS one 11 (4), e0154166, 2016 | 57 | 2016 |
A laboratory-scale model cocoa fermentation using dried, unfermented beans and artificial pulp can simulate the microbial and chemical changes of on-farm cocoa fermentation AH Lee, AP Neilson, SF O’Keefe, JA Ogejo, H Huang, M Ponder, ... European Food Research and Technology 245, 511-519, 2019 | 52 | 2019 |
Evolution of Fitness Cost-Neutral Mutant PfCRT Conferring P. falciparum 4-Aminoquinoline Drug Resistance Is Accompanied by Altered Parasite Metabolism and … SJ Gabryszewski, SK Dhingra, JM Combrinck, IA Lewis, PS Callaghan, ... PLoS pathogens 12 (11), e1005976, 2016 | 50 | 2016 |
Development and characterization of a pilot-scale model cocoa fermentation system suitable for studying the impact of fermentation on putative bioactive compounds and … KC Racine, AH Lee, BD Wiersema, H Huang, JD Lambert, AC Stewart, ... Foods 8 (3), 102, 2019 | 39 | 2019 |
Evidence for Regulation of Hemoglobin Metabolism and Intracellular Ionic Flux by the Plasmodium falciparum Chloroquine Resistance Transporter AH Lee, SK Dhingra, IA Lewis, MK Singh, A Siriwardana, S Dalal, ... Scientific reports 8 (1), 13578, 2018 | 35 | 2018 |
Miscible Polyether/Poly (ether–acetal) Electrolyte Blends KW Gao, WS Loo, RL Snyder, BA Abel, Y Choo, A Lee, SCM Teixeira, ... Macromolecules 53 (14), 5728-5739, 2020 | 29 | 2020 |
Persistence of Multitasking Distraction Following the Use of Smartphone-Based Clickers. S Ma, DG Steger, PE Doolittle, AH Lee, LE Griffin, A Stewart International Journal of Teaching and Learning in Higher Education 32 (1), 64-72, 2020 | 22 | 2020 |
Flavanol polymerization is a superior predictor of α-glucosidase inhibitory activity compared to flavanol or total polyphenol concentrations in cocoas prepared by variations in … KC Racine, BD Wiersema, LE Griffin, LA Essenmacher, AH Lee, H Hopfer, ... Antioxidants 8 (12), 635, 2019 | 17 | 2019 |
Development of a rapid ultra performance hydrophilic interaction liquid chromatography tandem mass spectrometry method for procyanidins with enhanced ionization efficiency KC Racine, AH Lee, AC Stewart, KW Blakeslee, AP Neilson Journal of Chromatography A 1594, 54-64, 2019 | 15 | 2019 |
Axicabtagene ciloleucel (Axi-Cel) in patients with relapsed/refractory indolent non-Hodgkin lymphoma: 4-year follow-up from the phase 2 ZUMA-5 trial SS Neelapu, JC Chavez, AR Sehgal, N Epperla, ML Ulrickson, E Bachy, ... Blood 142, 4868, 2023 | 11 | 2023 |
Genome editing: insights from chemical biology to support safe and transformative therapeutic applications RD Wegrzyn, AH Lee, AL Jenkins, CD Stoddard, AE Cheever ACS chemical biology 13 (2), 333-342, 2018 | 10 | 2018 |