Targeting cancer signaling pathways by natural products: Exploring promising anti-cancer agents S Hashem, TA Ali, S Akhtar, S Nisar, G Sageena, S Ali, S Al-Mannai, ... Biomedicine & Pharmacotherapy 150, 113054, 2022 | 233 | 2022 |
Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy AA Bhat, S Nisar, S Maacha, TC Carneiro-Lobo, S Akhtar, KS Siveen, ... Molecular cancer 20, 1-20, 2021 | 107 | 2021 |
Genetics of glutamate and its receptors in autism spectrum disorder S Nisar, AA Bhat, T Masoodi, S Hashem, S Akhtar, TA Ali, S Amjad, ... Molecular psychiatry 27 (5), 2380-2392, 2022 | 102 | 2022 |
Reactive oxygen species (ROS) in cancer pathogenesis and therapy: An update on the role of ROS in anticancer action of benzophenanthridine alkaloids AQ Khan, K Rashid, AA AlAmodi, MV Agha, S Akhtar, I Hakeem, SS Raza, ... Biomedicine & Pharmacotherapy 143, 112142, 2021 | 101 | 2021 |
Curcumin induces apoptotic cell death via inhibition of PI3-kinase/AKT pathway in B-precursor acute lymphoblastic leukemia S Kuttikrishnan, KS Siveen, KS Prabhu, AQ Khan, EI Ahmed, S Akhtar, ... Frontiers in oncology 9, 484, 2019 | 82 | 2019 |
Dysregulated FOXM1 signaling in the regulation of cancer stem cells G Sher, T Masoodi, K Patil, S Akhtar, S Kuttikrishnan, A Ahmad, S Uddin Seminars in cancer biology 86, 107-121, 2022 | 65 | 2022 |
The plasticity of pancreatic cancer stem cells: Implications in therapeutic resistance K Patil, FB Khan, S Akhtar, A Ahmad, S Uddin Cancer and Metastasis Reviews 40 (3), 691-720, 2021 | 58 | 2021 |
Sanguinarine induces apoptosis pathway in multiple myeloma cell lines via inhibition of the JaK2/STAT3 signaling S Akhtar, IW Achkar, KS Siveen, S Kuttikrishnan, KS Prabhu, AQ Khan, ... Frontiers in Oncology 9, 285, 2019 | 44 | 2019 |
Sanguinarine suppresses growth and induces apoptosis in childhood acute lymphoblastic leukemia S Kuttikrishnan, KS Siveen, KS Prabhu, AQ Khan, S Akhtar, JM Mateo, ... Leukemia & Lymphoma 60 (3), 782-794, 2019 | 40 | 2019 |
Cross-talk between the microbiome and chronic inflammation in esophageal cancer: potential driver of oncogenesis T Sharma, A Gupta, R Chauhan, AA Bhat, S Nisar, S Hashem, S Akhtar, ... Cancer and Metastasis Reviews 41 (2), 281-299, 2022 | 39 | 2022 |
Epigenetic regulation of cancer stem cells by the aryl hydrocarbon receptor pathway S Akhtar, S Hourani, L Therachiyil, A Al-Dhfyan, A Agouni, A Zeidan, ... Seminars in cancer biology 83, 177-196, 2022 | 37 | 2022 |
Exosomes: emerging diagnostic and therapeutic targets in cutaneous diseases AQ Khan, S Akhtar, KS Prabhu, L Zarif, R Khan, M Alam, J Buddenkotte, ... International Journal of Molecular Sciences 21 (23), 9264, 2020 | 33 | 2020 |
Embelin: a benzoquinone possesses therapeutic potential for the treatment of human cancer KS Prabhu, IW Achkar, S Kuttikrishnan, S Akhtar, AQ Khan, KS Siveen, ... Future medicinal chemistry 10 (8), 961-976, 2018 | 31 | 2018 |
EGFR inhibitor gefitinib induces cardiotoxicity through the modulation of cardiac PTEN/Akt/FoxO3a pathway and reactive metabolites formation: in vivo and in vitro rat studies A Alhoshani, FE Alanazi, MR Alotaibi, MW Attwa, AA Kadi, A Aldhfyan, ... Chemical research in toxicology 33 (7), 1719-1728, 2020 | 30 | 2020 |
Cytokine-mediated dysregulation of signaling pathways in the pathogenesis of multiple myeloma S Akhtar, TA Ali, A Faiyaz, OS Khan, SS Raza, M Kulinski, HE Omri, ... International Journal of Molecular Sciences 21 (14), 5002, 2020 | 29 | 2020 |
Curcumin-mediated degradation of S-phase kinase protein 2 induces cytotoxic effects in human papillomavirus-positive and negative squamous carcinoma cells AQ Khan, KS Siveen, KS Prabhu, S Kuttikrishnan, S Akhtar, A Shaar, ... Frontiers in Oncology 8, 399, 2018 | 27 | 2018 |
Epigenetic control of inflammation in Atopic Dermatitis S Akhtar, RKME Alsayed, F Ahmad, A AlHammadi, S Al-Khawaga, ... Seminars in Cell & Developmental Biology 154, 199-207, 2024 | 15 | 2024 |
Role of HMGB1 and its associated signaling pathways in human malignancies S Idoudi, T Bedhiafi, S Pedersen, M Elahtem, I Alremawi, S Akhtar, ... Cellular Signalling, 110904, 2023 | 9 | 2023 |
Guggulsterone induces apoptosis in multiple myeloma cells by targeting high mobility group box 1 via janus activated kinase/signal transducer and activator of transcription pathway S Akhtar, L Zarif, S Kuttikrishnan, KS Prabhu, K Patil, S Nisar, ... Cancers 14 (22), 5621, 2022 | 6 | 2022 |
Role of animal research in human malignancies AQ Khan, KS Siveen, KS Prabhu, S Kuttikrishnan, S Akhtar, ... Animal models in cancer drug discovery, 1-29, 2019 | 5 | 2019 |