| High-resolution CRISPR screens reveal fitness genes and genotype-specific cancer liabilities T Hart, M Chandrashekhar, M Aregger, Z Steinhart, KR Brown, ... Cell 163 (6), 1515-1526, 2015 | 1713 | 2015 |
| Comprehensive functional maps of the antigen-binding site of an anti-ErbB2 antibody obtained with shotgun scanning mutagenesis FF Vajdos, CW Adams, TN Breece, LG Presta, AM de Vos, SS Sidhu Journal of molecular biology 320 (2), 415-428, 2002 | 868 | 2002 |
| Beyond natural antibodies: the power of in vitro display technologies ARM Bradbury, S Sidhu, S Dübel, J McCafferty Nature biotechnology 29 (3), 245-254, 2011 | 687 | 2011 |
| Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies K Newton, ML Matsumoto, IE Wertz, DS Kirkpatrick, JR Lill, J Tan, ... Cell 134 (4), 668-678, 2008 | 672 | 2008 |
| [21] Phage display for selection of novel binding peptides SS Sidhu, HB Lowman, BC Cunningham, JA Wells Methods in enzymology 328, 333-IN5, 2000 | 656 | 2000 |
| A specificity map for the PDZ domain family R Tonikian, Y Zhang, SL Sazinsky, B Currell, JH Yeh, B Reva, HA Held, ... PLoS biology 6 (9), e239, 2008 | 575 | 2008 |
| Visualization of arrestin recruitment by a G-protein-coupled receptor AK Shukla, GH Westfield, K Xiao, RI Reis, LY Huang, P Tripathi-Shukla, ... Nature 512 (7513), 218-222, 2014 | 549 | 2014 |
| Rapid mapping of protein functional epitopes by combinatorial alanine scanning GA Weiss, CK Watanabe, A Zhong, A Goddard, SS Sidhu Proceedings of the National Academy of Sciences 97 (16), 8950-8954, 2000 | 488 | 2000 |
| Synthetic antibodies from a four-amino-acid code: a dominant role for tyrosine in antigen recognition FA Fellouse, C Wiesmann, SS Sidhu Proceedings of the National Academy of Sciences 101 (34), 12467-12472, 2004 | 482 | 2004 |
| Phage display in pharmaceutical biotechnology SS Sidhu Current opinion in biotechnology 11 (6), 610-616, 2000 | 472 | 2000 |
| High-throughput generation of synthetic antibodies from highly functional minimalist phage-displayed libraries FA Fellouse, K Esaki, S Birtalan, D Raptis, VJ Cancasci, A Koide, ... Journal of molecular biology 373 (4), 924-940, 2007 | 469 | 2007 |
| High-affinity human antibodies from phage-displayed synthetic Fab libraries with a single framework scaffold CV Lee, WC Liang, MS Dennis, C Eigenbrot, SS Sidhu, G Fuh Journal of molecular biology 340 (5), 1073-1093, 2004 | 455 | 2004 |
| Neutralizing antibody and soluble ACE2 inhibition of a replication-competent VSV-SARS-CoV-2 and a clinical isolate of SARS-CoV-2 JB Case, PW Rothlauf, RE Chen, Z Liu, H Zhao, AS Kim, LM Bloyet, ... Cell host & microbe 28 (3), 475-485. e5, 2020 | 413 | 2020 |
| Intratumoral heterogeneity: pathways to treatment resistance and relapse in human glioblastoma MA Qazi, P Vora, C Venugopal, SS Sidhu, J Moffat, C Swanton, SK Singh Annals of Oncology 28 (7), 1448-1456, 2017 | 403 | 2017 |
| Engineering M13 for phage display SS Sidhu Biomolecular engineering 18 (2), 57-63, 2001 | 394 | 2001 |
| SynNotch-CAR T cells overcome challenges of specificity, heterogeneity, and persistence in treating glioblastoma JH Choe, PB Watchmaker, MS Simic, RD Gilbert, AW Li, NA Krasnow, ... Science translational medicine 13 (591), eabe7378, 2021 | 356 | 2021 |
| Phage-displayed antibody libraries of synthetic heavy chain complementarity determining regions SS Sidhu, B Li, Y Chen, FA Fellouse, C Eigenbrot, G Fuh Journal of Molecular biology 338 (2), 299-310, 2004 | 353 | 2004 |
| Synthetic antibody phage libraries G Fuh, SS Sidhu US Patent 7,985,840, 2011 | 349 | 2011 |
| A strategy for modulation of enzymes in the ubiquitin system A Ernst, G Avvakumov, J Tong, Y Fan, Y Zhao, P Alberts, A Persaud, ... Science 339 (6119), 590-595, 2013 | 339 | 2013 |
| Genome-wide CRISPR screens reveal a Wnt–FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors Z Steinhart, Z Pavlovic, M Chandrashekhar, T Hart, X Wang, X Zhang, ... Nature medicine 23 (1), 60-68, 2017 | 326 | 2017 |