| Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474 ACM van Esbroeck, APA Janssen, AB Cognetta III, D Ogasawara, ... Science 356 (6342), 1084-1087, 2017 | 344 | 2017 |
| Design, synthesis, enzyme-inhibitory activity, and effect on human cancer cells of a novel series of jumonji domain-containing protein 2 histone demethylase inhibitors S Hamada, T Suzuki, K Mino, K Koseki, F Oehme, I Flamme, H Ozasa, ... Journal of medicinal chemistry 53 (15), 5629-5638, 2010 | 190 | 2010 |
| Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition D Ogasawara, H Deng, A Viader, MP Baggelaar, A Breman, H den Dulk, ... Proceedings of the National Academy of Sciences 113 (1), 26-33, 2016 | 179 | 2016 |
| A chemical proteomic atlas of brain serine hydrolases identifies cell type-specific pathways regulating neuroinflammation A Viader, D Ogasawara, CM Joslyn, M Sanchez-Alavez, S Mori, ... Elife 5, e12345, 2016 | 106 | 2016 |
| Lysine-specific demethylase 1-selective inactivators: protein-targeted drug delivery mechanism. D Ogasawara, Y Itoh, H Tsumoto, T Kakizawa, K Mino, K Fukuhara, ... Angewandte Chemie International Edition 52 (33), 2013 | 102 | 2013 |
| Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice ED Mock, M Mustafa, O Gunduz-Cinar, R Cinar, GN Petrie, V Kantae, X Di, ... Nature chemical biology 16 (6), 667-675, 2020 | 78 | 2020 |
| Selective blockade of the lyso-PS lipase ABHD12 stimulates immune responses in vivo D Ogasawara, TA Ichu, VF Vartabedian, J Benthuysen, H Jing, A Reed, ... Nature chemical biology 14 (12), 1099-1108, 2018 | 69 | 2018 |
| An in vivo multiplexed small-molecule screening platform BM Grüner, CJ Schulze, D Yang, D Ogasawara, MM Dix, ZN Rogers, ... Nature methods 13 (10), 883-889, 2016 | 69 | 2016 |
| Synthesis and biological activity of optically active NCL-1, a lysine-specific demethylase 1 selective inhibitor D Ogasawara, T Suzuki, K Mino, R Ueda, MNA Khan, T Matsubara, ... Bioorganic & medicinal chemistry 19 (12), 3702-3708, 2011 | 66 | 2011 |
| Stress promotes drug seeking through glucocorticoid-dependent endocannabinoid mobilization in the prelimbic cortex JR McReynolds, EM Doncheck, Y Li, O Vranjkovic, EN Graf, D Ogasawara, ... Biological psychiatry 84 (2), 85-94, 2018 | 61 | 2018 |
| Proteomic discovery of chemical probes that perturb protein complexes in human cells MR Lazear, JR Remsberg, MG Jaeger, K Rothamel, H Her, KE DeMeester, ... Molecular cell 83 (10), 1725-1742. e12, 2023 | 55 | 2023 |
| Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan AL Chen, KM Lum, P Lara-Gonzalez, D Ogasawara, AB Cognetta III, A To, ... Nature chemical biology 15 (5), 453-462, 2019 | 49 | 2019 |
| Global portrait of protein targets of metabolites of the neurotoxic compound BIA 10–2474 Z Huang, D Ogasawara, UI Seneviratne, AB Cognetta III, CW Am Ende, ... ACS chemical biology 14 (2), 192-197, 2019 | 49 | 2019 |
| Positron emission tomography imaging of the endocannabinoid system: opportunities and challenges in radiotracer development L Hou, J Rong, A Haider, D Ogasawara, C Varlow, MA Schafroth, L Mu, ... Journal of medicinal chemistry 64 (1), 123-149, 2020 | 48 | 2020 |
| In situ identification of cellular drug targets in mammalian tissue Z Pang, MA Schafroth, D Ogasawara, Y Wang, V Nudell, NK Lal, D Yang, ... Cell 185 (10), 1793-1805. e17, 2022 | 47 | 2022 |
| Triazole ureas act as diacylglycerol lipase inhibitors and prevent fasting-induced refeeding H Deng, S Kooijman, AMCH van den Nieuwendijk, D Ogasawara, ... Journal of Medicinal Chemistry 60 (1), 428-440, 2017 | 47 | 2017 |
| Discovery of small-molecule enzyme activators by activity-based protein profiling BP Kok, S Ghimire, W Kim, S Chatterjee, T Johns, S Kitamura, J Eberhardt, ... Nature chemical biology 16 (9), 997-1005, 2020 | 42 | 2020 |
| Design, synthesis, and evaluation of reversible and irreversible monoacylglycerol lipase positron emission tomography (PET) tracers using a “tail switching” strategy on a … Z Chen, W Mori, X Deng, R Cheng, D Ogasawara, G Zhang, MA Schafroth, ... Journal of medicinal chemistry 62 (7), 3336-3353, 2019 | 42 | 2019 |
| In Vitro and in Vivo Evaluation of 11C-Labeled Azetidinecarboxylates for Imaging Monoacylglycerol Lipase by PET Imaging Studies R Cheng, W Mori, L Ma, M Alhouayek, A Hatori, Y Zhang, D Ogasawara, ... Journal of medicinal chemistry 61 (6), 2278-2291, 2018 | 42 | 2018 |
| N-acyl taurines are endogenous lipid messengers that improve glucose homeostasis TJ Grevengoed, SAJ Trammell, MK McKinney, N Petersen, RL Cardone, ... Proceedings of the National Academy of Sciences 116 (49), 24770-24778, 2019 | 39 | 2019 |
Takayoshi SuzukiOsaka UniversityVerified email at sanken.osaka-u.ac.jp
