Systematic comparison of 2A peptides for cloning multi-genes in a polycistronic vector Z Liu, O Chen, JBJ Wall, M Zheng, Y Zhou, L Wang, HR Vaseghi, L Qian, ... Scientific reports 7 (1), 1-9, 2017 | 816 | 2017 |
Stoichiometry of Gata4, Mef2c, and Tbx5 influences the efficiency and quality of induced cardiac myocyte reprogramming L Wang, Z Liu, C Yin, H Asfour, O Chen, Y Li, N Bursac, J Liu, L Qian Circulation research 116 (2), 237-244, 2015 | 258 | 2015 |
Single-cell transcriptomics reconstructs fate conversion from fibroblast to cardiomyocyte Z Liu, L Wang, JD Welch, H Ma, Y Zhou, HR Vaseghi, S Yu, JB Wall, ... Nature 551 (7678), 100-104, 2017 | 230 | 2017 |
Bmi1 is a key epigenetic barrier to direct cardiac reprogramming Y Zhou, L Wang, HR Vaseghi, Z Liu, R Lu, S Alimohamadi, C Yin, JD Fu, ... Cell stem cell 18 (3), 382-395, 2016 | 229 | 2016 |
Direct in vivo reprogramming with Sendai virus vectors improves cardiac function after myocardial infarction K Miyamoto, M Akiyama, F Tamura, M Isomi, H Yamakawa, T Sadahiro, ... Cell stem cell 22 (1), 91-103. e5, 2018 | 188 | 2018 |
Single-cell transcriptomic analyses of cell fate transitions during human cardiac reprogramming Y Zhou, Z Liu, JD Welch, X Gao, L Wang, T Garbutt, B Keepers, H Ma, ... Cell Stem Cell 25 (1), 149-164. e9, 2019 | 120 | 2019 |
Re-patterning of H3K27me3, H3K4me3 and DNA methylation during fibroblast conversion into induced cardiomyocytes Z Liu, O Chen, M Zheng, L Wang, Y Zhou, C Yin, J Liu, L Qian Stem cell research 16 (2), 507-518, 2016 | 115 | 2016 |
Comparative Gene Expression Analyses Reveal Distinct Molecular Signatures between Differentially Reprogrammed Cardiomyocytes Y Zhou, L Wang, Z Liu, S Alimohamadi, C Yin, J Liu, L Qian Cell reports 20 (13), 3014-3024, 2017 | 77 | 2017 |
In vivo cardiac reprogramming using an optimal single polycistronic construct H Ma, L Wang, C Yin, J Liu, L Qian Cardiovascular research 108 (2), 217-219, 2015 | 67 | 2015 |
Identification of SERPINB1 as a physiological inhibitor of human granzyme H L Wang, Q Li, L Wu, S Liu, Y Zhang, X Yang, P Zhu, H Zhang, K Zhang, ... The Journal of Immunology 190 (3), 1319-1330, 2013 | 55 | 2013 |
Diabetes exacerbates myocardial ischemia/reperfusion injury by down-regulation of microRNA and up-regulation of O-GlcNAcylation D Wang, X Hu, SH Lee, F Chen, K Jiang, Z Tu, Z Liu, J Du, L Wang, C Yin, ... JACC: Basic to Translational Science 3 (3), 350-362, 2018 | 52 | 2018 |
Human innate responses and adjuvant activity of TLR ligands in vivo in mice reconstituted with a human immune system L Cheng, Z Zhang, G Li, F Li, L Wang, L Zhang, SM Zurawski, G Zurawski, ... Vaccine 35 (45), 6143-6153, 2017 | 52 | 2017 |
miR-24 regulates intrinsic apoptosis pathway in mouse cardiomyocytes L Wang, L Qian PLoS One 9 (1), e85389, 2014 | 52 | 2014 |
Down-regulation of Beclin1 promotes direct cardiac reprogramming L Wang, H Ma, P Huang, Y Xie, D Near, H Wang, J Xu, Y Yang, Y Xu, ... Science Translational Medicine 12 (566), 2020 | 51 | 2020 |
Targeting Mll1 H3K4 methyltransferase activity to guide cardiac lineage specific reprogramming of fibroblasts L Liu, I Lei, H Karatas, Y Li, L Wang, L Gnatovskiy, Y Dou, S Wang, L Qian, ... Cell discovery 2 (1), 1-11, 2016 | 46 | 2016 |
Cytosolic carboxypeptidase CCP6 is required for megakaryopoiesis by modulating Mad2 polyglutamylation B Ye, C Li, Z Yang, Y Wang, J Hao, L Wang, Y Li, Y Du, L Hao, B Liu, ... Journal of Experimental Medicine 211 (12), 2439-2454, 2014 | 44 | 2014 |
Granzyme H of cytotoxic lymphocytes is required for clearance of the hepatitis B virus through cleavage of the hepatitis B virus X protein H Tang, C Li, L Wang, H Zhang, Z Fan The Journal of Immunology 188 (2), 824-831, 2012 | 44 | 2012 |
Improved generation of induced cardiomyocytes using a polycistronic construct expressing optimal ratio of Gata4, Mef2c and Tbx5 L Wang, Z Liu, C Yin, Y Zhou, J Liu, L Qian Journal of visualized experiments: JoVE, 2015 | 40 | 2015 |
A Loss of Function Screen of Epigenetic Modifiers and Splicing Factors during Early Stage of Cardiac Reprogramming Y Zhou, S Alimohamadi, L Wang, Z Liu, JB Wall, C Yin, J Liu, L Qian Stem cells international 2018, 2018 | 31 | 2018 |
Structural basis for proteolytic specificity of the human apoptosis-inducing granzyme M L Wu, L Wang, G Hua, K Liu, X Yang, Y Zhai, M Bartlam, F Sun, Z Fan The Journal of Immunology 183 (1), 421-429, 2009 | 31 | 2009 |