MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling PA da Costa Martins, K Salic, MM Gladka, AS Armand, S Leptidis, ... Nature cell biology 12 (12), 1220-1227, 2010 | 410 | 2010 |
Conditional Dicer Gene Deletion in the Postnatal Myocardium Provokes Spontaneous Cardiac Remodeling PA da Costa Martins, M Bourajjaj, M Gladka, M Kortland, RJ van Oort, ... Circulation 118 (15), 1567-1576, 2008 | 385 | 2008 |
Circulating miR-29a, among other up-regulated microRNAs, is the only biomarker for both hypertrophy and fibrosis in patients with hypertrophic cardiomyopathy R Roncarati, C Viviani Anselmi, MA Losi, L Papa, E Cavarretta, ... Journal of the American College of Cardiology 63 (9), 920-927, 2014 | 372 | 2014 |
Native and bioengineered extracellular vesicles for cardiovascular therapeutics RC de Abreu, H Fernandes, PA da Costa Martins, S Sahoo, C Emanueli, ... Nature reviews cardiology 17 (11), 685-697, 2020 | 358 | 2020 |
Regulation of fetal gene expression in heart failure E Dirkx, PA da Costa Martins, LJ De Windt Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (12 …, 2013 | 337 | 2013 |
Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis MOJ Grootaert, PA da Costa Martins, N Bitsch, I Pintelon, GRY De Meyer, ... Autophagy 11 (11), 2014-2032, 2015 | 284 | 2015 |
The hypoxia-inducible microRNA cluster miR-199a∼ 214 targets myocardial PPARδ and impairs mitochondrial fatty acid oxidation H El Azzouzi, S Leptidis, E Dirkx, J Hoeks, B van Bree, K Brand, ... Cell metabolism 18 (3), 341-354, 2013 | 228 | 2013 |
NFATc2 is a necessary mediator of calcineurin-dependent cardiac hypertrophy and heart failure M Bourajjaj, AS Armand, PA da Costa Martins, B Weijts, R van der Nagel, ... Journal of Biological Chemistry 283 (32), 22295-22303, 2008 | 204 | 2008 |
MicroRNAs in control of cardiac hypertrophy PA Da Costa Martins, LJ De Windt Cardiovascular research 93 (4), 563-572, 2012 | 185 | 2012 |
P-selectin glycoprotein ligand-1 is expressed on endothelial cells and mediates monocyte adhesion to activated endothelium P da Costa Martins, JJ García-Vallejo, JV Van Thienen, ... Arteriosclerosis, thrombosis, and vascular biology 27 (5), 1023-1029, 2007 | 167 | 2007 |
Nfat and miR-25 cooperate to reactivate the transcription factor Hand2 in heart failure E Dirkx, MM Gladka, LE Philippen, AS Armand, V Kinet, S Leptidis, ... Nature cell biology 15 (11), 1282-1293, 2013 | 165 | 2013 |
Protection against renal ischemia reperfusion injury by CD44 disruption KMA Rouschop, JJTH Roelofs, N Claessen, P da Costa Martins, ... Journal of the American Society of Nephrology 16 (7), 2034-2043, 2005 | 164 | 2005 |
Platelet-monocyte complexes support monocyte adhesion to endothelium by enhancing secondary tethering and cluster formation P da Costa Martins, N Van Den Berk, LH Ulfman, L Koenderman, ... Arteriosclerosis, thrombosis, and vascular biology 24 (1), 193-199, 2004 | 149 | 2004 |
Long COVID and the cardiovascular system—elucidating causes and cellular mechanisms in order to develop targeted diagnostic and therapeutic strategies: a joint Scientific … M Gyöngyösi, P Alcaide, FW Asselbergs, BJJM Brundel, GG Camici, ... Cardiovascular research 119 (2), 336-356, 2023 | 136 | 2023 |
A deep sequencing approach to uncover the miRNOME in the human heart S Leptidis, H El Azzouzi, SI Lok, R de Weger, S Olieslagers, N Kisters, ... PloS one 8 (2), e57800, 2013 | 124 | 2013 |
Cooperative Synergy between NFAT and MyoD Regulates Myogenin Expression and Myogenesis∗ AS Armand, M Bourajjaj, S Martínez-Martínez, H el Azzouzi, ... Journal of Biological Chemistry 283 (43), 29004-29010, 2008 | 103 | 2008 |
Targeting miR-423-5p reverses exercise training–induced HCN4 channel remodeling and sinus bradycardia A D’Souza, CM Pearman, Y Wang, S Nakao, SJRJ Logantha, C Cox, ... Circulation research 121 (9), 1058-1068, 2017 | 101 | 2017 |
Genetics and epigenetics of arrhythmia and heart failure B Duygu, EM Poels, PA Costa Martins Frontiers in genetics 4, 219, 2013 | 91 | 2013 |
DC-SIGN mediates adhesion and rolling of dendritic cells on primary human umbilical vein endothelial cells through LewisY antigen expressed on ICAM-2 JJ García-Vallejo, E van Liempt, P da Costa Martins, C Beckers, ... Molecular immunology 45 (8), 2359-2369, 2008 | 91 | 2008 |
Small changes can make a big difference—MicroRNA regulation of cardiac hypertrophy MM Gladka, PA da Costa Martins, LJ De Windt Journal of molecular and cellular cardiology 52 (1), 74-82, 2012 | 90 | 2012 |