Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine W Tai, L He, X Zhang, J Pu, D Voronin, S Jiang, Y Zhou, L Du Cellular & molecular immunology 17 (6), 613-620, 2020 | 1987 | 2020 |
Molecular mechanism for antibody-dependent enhancement of coronavirus entry Y Wan, J Shang, S Sun, W Tai, J Chen, Q Geng, L He, Y Chen, J Wu, ... Journal of virology 94 (5), 10.1128/jvi. 02015-19, 2020 | 861 | 2020 |
A novel receptor-binding domain (RBD)-based mRNA vaccine against SARS-CoV-2 W Tai, X Zhang, A Drelich, J Shi, JC Hsu, L Luchsinger, CD Hillyer, ... Cell research 30 (10), 932-935, 2020 | 159 | 2020 |
Cryo-electron microscopy structure of porcine deltacoronavirus spike protein in the prefusion state J Shang, Y Zheng, Y Yang, C Liu, Q Geng, W Tai, L Du, Y Zhou, W Zhang, ... Journal of virology 92 (4), 10.1128/jvi. 01556-17, 2018 | 140 | 2018 |
Introduction of neutralizing immunogenicity index to the rational design of MERS coronavirus subunit vaccines L Du, W Tai, Y Yang, G Zhao, Q Zhu, S Sun, C Liu, X Tao, CTK Tseng, ... Nature communications 7 (1), 13473, 2016 | 129 | 2016 |
Identification of SARS-CoV RBD-targeting monoclonal antibodies with cross-reactive or neutralizing activity against SARS-CoV-2 W Tai, X Zhang, Y He, S Jiang, L Du Antiviral research 179, 104820, 2020 | 128 | 2020 |
Vaccines for the prevention against the threat of MERS-CoV L Du, W Tai, Y Zhou, S Jiang Expert review of vaccines 15 (9), 1123-1134, 2016 | 122 | 2016 |
A recombinant receptor-binding domain of MERS-CoV in trimeric form protects human dipeptidyl peptidase 4 (hDPP4) transgenic mice from MERS-CoV infection W Tai, G Zhao, S Sun, Y Guo, Y Wang, X Tao, CTK Tseng, F Li, S Jiang, ... Virology 499, 375-382, 2016 | 116 | 2016 |
Biomechanical characterization of SARS-CoV-2 spike RBD and human ACE2 protein-protein interaction W Cao, C Dong, S Kim, D Hou, W Tai, L Du, W Im, XF Zhang Biophysical journal 120 (6), 1011-1019, 2021 | 110 | 2021 |
A novel nanobody targeting Middle East respiratory syndrome coronavirus (MERS-CoV) receptor-binding domain has potent cross-neutralizing activity and protective efficacy … G Zhao, L He, S Sun, H Qiu, W Tai, J Chen, J Li, Y Chen, Y Guo, Y Wang, ... Journal of virology 92 (18), 10.1128/jvi. 00837-18, 2018 | 106 | 2018 |
Recombinant receptor-binding domains of multiple Middle East respiratory syndrome coronaviruses (MERS-CoVs) induce cross-neutralizing antibodies against divergent human and … W Tai, Y Wang, CA Fett, G Zhao, F Li, S Perlman, S Jiang, Y Zhou, L Du Journal of virology 91 (1), 10.1128/jvi. 01651-16, 2017 | 95 | 2017 |
Engineering a stable CHO cell line for the expression of a MERS-coronavirus vaccine antigen MP Nyon, L Du, CTK Tseng, CA Seid, J Pollet, KS Naceanceno, ... Vaccine 36 (14), 1853-1862, 2018 | 76 | 2018 |
Novel virus-like nanoparticle vaccine effectively protects animal model from SARS-CoV-2 infection Q Geng, W Tai, VK Baxter, J Shi, Y Wan, X Zhang, SA Montgomery, ... PLoS pathogens 17 (9), e1009897, 2021 | 72 | 2021 |
Receptor-binding domain of MERS-CoV with optimal immunogen dosage and immunization interval protects human transgenic mice from MERS-CoV infection Y Wang, W Tai, J Yang, G Zhao, S Sun, CTK Tseng, S Jiang, Y Zhou, L Du, ... Human vaccines & immunotherapeutics 13 (7), 1615-1624, 2017 | 65 | 2017 |
Identification of novel natural products as effective and broad-spectrum anti-Zika virus inhibitors Y Gao, W Tai, N Wang, X Li, S Jiang, AK Debnath, L Du, S Chen Viruses 11 (11), 1019, 2019 | 62 | 2019 |
Inhalation delivery of dexamethasone with iSEND nanoparticles attenuates the COVID-19 cytokine storm in mice and nonhuman primates QF Meng, W Tai, M Tian, X Zhuang, Y Pan, J Lai, Y Xu, Z Xu, M Li, G Zhao, ... Science Advances 9 (24), eadg3277, 2023 | 60 | 2023 |
Single-dose treatment with a humanized neutralizing antibody affords full protection of a human transgenic mouse model from lethal Middle East respiratory syndrome (MERS … H Qiu, S Sun, H Xiao, J Feng, Y Guo, W Tai, Y Wang, L Du, G Zhao, ... Antiviral research 132, 141-148, 2016 | 60 | 2016 |
Critical neutralizing fragment of Zika virus EDIII elicits cross-neutralization and protection against divergent Zika viruses W Tai, L He, Y Wang, S Sun, G Zhao, C Luo, P Li, H Zhao, DH Fremont, ... Emerging microbes & infections 7 (1), 1-8, 2018 | 56 | 2018 |
Neutralization of Zika virus by germline-like human monoclonal antibodies targeting cryptic epitopes on envelope domain III Y Wu, S Li, L Du, C Wang, P Zou, B Hong, M Yuan, X Ren, W Tai, Y Kong, ... Emerging microbes & infections 6 (1), 1-11, 2017 | 56 | 2017 |
The development of Nanosota-1 as anti-SARS-CoV-2 nanobody drug candidates G Ye, J Gallant, J Zheng, C Massey, K Shi, W Tai, A Odle, M Vickers, ... Elife 10, e64815, 2021 | 51 | 2021 |