| Necroptosis and RIPK1-mediated neuroinflammation in CNS diseases J Yuan, P Amin, D Ofengeim Nature Reviews Neuroscience 20 (1), 19-33, 2019 | 767 | 2019 |
| RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS Y Ito, D Ofengeim, A Najafov, S Das, S Saberi, Y Li, J Hitomi, H Zhu, ... Science 353 (6299), 603-608, 2016 | 578 | 2016 |
| Activation of necroptosis in multiple sclerosis D Ofengeim, Y Ito, A Najafov, Y Zhang, B Shan, JP DeWitt, J Ye, X Zhang, ... Cell reports 10 (11), 1836-1849, 2015 | 530 | 2015 |
| TBK1 suppresses RIPK1-driven apoptosis and inflammation during development and in aging D Xu, T Jin, H Zhu, H Chen, D Ofengeim, C Zou, L Mifflin, L Pan, P Amin, ... Cell 174 (6), 1477-1491. e19, 2018 | 393 | 2018 |
| Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis J Geng, Y Ito, L Shi, P Amin, J Chu, AT Ouchida, AK Mookhtiar, H Zhao, ... Nature communications 8 (1), 359, 2017 | 275 | 2017 |
| Regulation of a distinct activated RIPK1 intermediate bridging complex I and complex II in TNFα-mediated apoptosis P Amin, M Florez, A Najafov, H Pan, J Geng, D Ofengeim, SA Dziedzic, ... Proceedings of the National Academy of Sciences 115 (26), E5944-E5953, 2018 | 149 | 2018 |
| Sequential activation of necroptosis and apoptosis cooperates to mediate vascular and neural pathology in stroke MG Naito, D Xu, P Amin, J Lee, H Wang, W Li, M Kelliher, M Pasparakis, ... Proceedings of the National Academy of Sciences 117 (9), 4959-4970, 2020 | 131 | 2020 |
| TAM kinases promote necroptosis by regulating oligomerization of MLKL A Najafov, AK Mookhtiar, HS Luu, A Ordureau, H Pan, PP Amin, Y Li, Q Lu, ... Molecular cell 75 (3), 457-468. e4, 2019 | 121 | 2019 |
| ABIN-1 regulates RIPK1 activation by linking Met1 ubiquitylation with Lys63 deubiquitylation in TNF-RSC SA Dziedzic, Z Su, V Jean Barrett, A Najafov, AK Mookhtiar, P Amin, ... Nature cell biology 20 (1), 58-68, 2018 | 97 | 2018 |
| Modulating TRADD to restore cellular homeostasis and inhibit apoptosis D Xu, H Zhao, M Jin, H Zhu, B Shan, J Geng, SA Dziedzic, P Amin, ... Nature 587 (7832), 133-138, 2020 | 84 | 2020 |
| S-nitrosylation regulates nuclear translocation of chloride intracellular channel protein CLIC4 M Malik, A Shukla, P Amin, W Niedelman, J Lee, K Jividen, JM Phang, ... Journal of Biological Chemistry 285 (31), 23818-23828, 2010 | 47 | 2010 |
| RIPK1 promotes energy sensing by the mTORC1 pathway A Najafov, HS Luu, AK Mookhtiar, L Mifflin, H Xia, PP Amin, A Ordureau, ... Molecular Cell 81 (2), 370-385. e7, 2021 | 36 | 2021 |
| Realizing the promise of immunotherapy: A global plan for action E Capra, P Amin, J Alford, D Thompson, N Davies, G Griffiths The World Innovation Summit for Health (WISH), 2020 | | 2020 |
| Regulation of RIPK1 Dependent Apoptosis and Necroptosis PP Amin Harvard University, 2017 | | 2017 |