| Q&A: What are exosomes, exactly? JR Edgar BMC biology 14, 1-7, 2016 | 424 | 2016 |
| Hrs‐and CD63‐dependent competing mechanisms make different sized endosomal intraluminal vesicles JR Edgar, ER Eden, CE Futter Traffic 15 (2), 197-211, 2014 | 252 | 2014 |
| Tetherin is an exosomal tether JR Edgar, PT Manna, S Nishimura, G Banting, MS Robinson Elife 5, e17180, 2016 | 191 | 2016 |
| Defects in ER–endosome contacts impact lysosome function in hereditary spastic paraplegia R Allison, JR Edgar, G Pearson, T Rizo, T Newton, S Günther, F Berner, ... Journal of Cell Biology 216 (5), 1337-1355, 2017 | 167 | 2017 |
| AP-4 vesicles contribute to spatial control of autophagy via RUSC-dependent peripheral delivery of ATG9A AK Davies, DN Itzhak, JR Edgar, TL Archuleta, J Hirst, LP Jackson, ... Nature communications 9 (1), 3958, 2018 | 138 | 2018 |
| Interaction between AP-5 and the hereditary spastic paraplegia proteins SPG11 and SPG15 J Hirst, GHH Borner, J Edgar, MY Hein, M Mann, F Buchholz, R Antrobus, ... Molecular biology of the cell 24 (16), 2558-2569, 2013 | 134 | 2013 |
| Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology EL Clayton, S Mizielinska, JR Edgar, TT Nielsen, S Marshall, FE Norona, ... Acta neuropathologica 130, 511-523, 2015 | 103 | 2015 |
| ESCRTs regulate amyloid precursor protein sorting in multivesicular bodies and intracellular amyloid-β accumulation JR Edgar, K Willén, GK Gouras, CE Futter Journal of cell science 128 (14), 2520-2528, 2015 | 99 | 2015 |
| Loss of AP-5 results in accumulation of aberrant endolysosomes: defining a new type of lysosomal storage disease J Hirst, JR Edgar, T Esteves, F Darios, M Madeo, J Chang, RH Roda, ... Human molecular genetics 24 (17), 4984-4996, 2015 | 91 | 2015 |
| Aβ accumulation causes MVB enlargement and is modelled by dominant negative VPS4A K Willén, JR Edgar, T Hasegawa, N Tanaka, CE Futter, GK Gouras Molecular neurodegeneration 12, 1-18, 2017 | 81 | 2017 |
| Compartmentalized synthesis of triacylglycerol at the inner nuclear membrane regulates nuclear organization AD Barbosa, K Lim, M Mari, JR Edgar, L Gal, P Sterk, BJ Jenkins, ... Developmental Cell 50 (6), 755-766. e6, 2019 | 72 | 2019 |
| Fractionation profiling: a fast and versatile approach for mapping vesicle proteomes and protein–protein interactions GHH Borner, MY Hein, J Hirst, JR Edgar, M Mann, MS Robinson Molecular biology of the cell 25 (20), 3178-3194, 2014 | 51 | 2014 |
| De novo VPS4A mutations cause multisystem disease with abnormal neurodevelopment C Rodger, E Flex, RJ Allison, A Sanchis-Juan, MA Hasenahuer, ... The American Journal of Human Genetics 107 (6), 1129-1148, 2020 | 50 | 2020 |
| Contribution of the clathrin adaptor AP-1 subunit µ1 to acidic cluster protein sorting P Navarro Negredo, JR Edgar, AG Wrobel, NR Zaccai, R Antrobus, ... Journal of Cell Biology 216 (9), 2927-2943, 2017 | 48 | 2017 |
| Contributions of epsinR and gadkin to clathrin-mediated intracellular trafficking J Hirst, JR Edgar, GHH Borner, S Li, DA Sahlender, R Antrobus, ... Molecular biology of the cell 26 (17), 3085-3103, 2015 | 46 | 2015 |
| Frontotemporal dementia causative CHMP2B impairs neuronal endolysosomal traffic-rescue by TMEM106B knockdown EL Clayton, C Milioto, B Muralidharan, FE Norona, JR Edgar, A Soriano, ... Brain 141 (12), 3428-3442, 2018 | 42 | 2018 |
| The WDR11 complex facilitates the tethering of AP-1-derived vesicles P Navarro Negredo, JR Edgar, PT Manna, R Antrobus, MS Robinson Nature communications 9 (1), 596, 2018 | 42 | 2018 |
| Fas Ligand localizes to intraluminal vesicles within NK cell cytolytic granules and is enriched at the immune synapse J Lee, NMG Dieckmann, JR Edgar, GM Griffiths, RM Siegel Immunity, inflammation and disease 6 (2), 312-321, 2018 | 38 | 2018 |
| Complicated spastic paraplegia in patients with AP5Z1 mutations (SPG48) J Hirst, M Madeo, K Smets, JR Edgar, L Schols, J Li, A Yarrow, ... Neurology: Genetics 2 (5), e98, 2016 | 38 | 2016 |
| Molecular mechanisms of disease pathogenesis differ in Krabbe disease variants SJ Spratley, CH Hill, AH Viuff, JR Edgar, K Skjødt, JE Deane Traffic 17 (8), 908-922, 2016 | 38 | 2016 |