| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 11254 | 2021 |
| TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity MU Gack, YC Shin, CH Joo, T Urano, C Liang, L Sun, O Takeuchi, S Akira, ... Nature 446 (7138), 916-920, 2007 | 1951 | 2007 |
| RIG-I-like receptors: their regulation and roles in RNA sensing J Rehwinkel, MU Gack Nature Reviews Immunology 20 (9), 537-551, 2020 | 1422 | 2020 |
| Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I MU Gack, RA Albrecht, T Urano, KS Inn, IC Huang, E Carnero, M Farzan, ... Cell host & microbe 5 (5), 439-449, 2009 | 1047 | 2009 |
| Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking C Liang, J Lee, KS Inn, MU Gack, Q Li, EA Roberts, I Vergne, V Deretic, ... Nature cell biology 10 (7), 776-787, 2008 | 963 | 2008 |
| Dysregulation of type I interferon responses in COVID-19 D Acharya, GQ Liu, MU Gack Nature Reviews Immunology 20 (7), 397-398, 2020 | 497 | 2020 |
| Viral evasion of intracellular DNA and RNA sensing YK Chan, MU Gack Nature Reviews Microbiology 14 (6), 360-373, 2016 | 493 | 2016 |
| Cytosolic viral sensor RIG-I is a 5'-Triphosphate–dependent translocase on double-stranded RNA S Myong, S Cui, PV Cornish, A Kirchhofer, MU Gack, JU Jung, ... Science 323 (5917), 1070-1074, 2009 | 464 | 2009 |
| Dephosphorylation of the RNA sensors RIG-I and MDA5 by the phosphatase PP1 is essential for innate immune signaling E Wies, MK Wang, NP Maharaj, K Chen, S Zhou, RW Finberg, MU Gack Immunity 38 (3), 437-449, 2013 | 356 | 2013 |
| Species-specific inhibition of RIG-I ubiquitination and IFN induction by the influenza A virus NS1 protein R Rajsbaum, RA Albrecht, MK Wang, NP Maharaj, GA Versteeg, ... PLoS pathogens 8 (11), e1003059, 2012 | 353 | 2012 |
| Roles of RIG-I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction MU Gack, A Kirchhofer, YC Shin, KS Inn, C Liang, S Cui, S Myong, T Ha, ... Proceedings of the National Academy of Sciences 105 (43), 16743-16748, 2008 | 319 | 2008 |
| TRIM proteins and their roles in antiviral host defenses M van Gent, KMJ Sparrer, MU Gack Annual review of virology 5 (1), 385-405, 2018 | 316 | 2018 |
| ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity GQ Liu, JH Lee, ZM Parker, D Acharya, JJ Chiang, M van Gent, W Riedl, ... Nature microbiology 6 (4), 467-478, 2021 | 266 | 2021 |
| Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I-mediated immunity JJ Chiang, KMJ Sparrer, M van Gent, C Lässig, T Huang, N Osterrieder, ... Nature immunology 19 (1), 53-62, 2018 | 247 | 2018 |
| Linear ubiquitin assembly complex negatively regulates RIG-I-and TRIM25-mediated type I interferon induction KS Inn, MU Gack, F Tokunaga, M Shi, LY Wong, K Iwai, JU Jung Molecular cell 41 (3), 354-365, 2011 | 237 | 2011 |
| A network medicine approach to investigation and population-based validation of disease manifestations and drug repurposing for COVID-19 Y Zhou, Y Hou, J Shen, R Mehra, A Kallianpur, DA Culver, MU Gack, ... PLoS biology 18 (11), e3000970, 2020 | 210 | 2020 |
| Ubiquitination in the antiviral immune response ME Davis, MU Gack Virology 479, 52-65, 2015 | 199 | 2015 |
| TRIM23 mediates virus-induced autophagy via activation of TBK1 KMJ Sparrer, S Gableske, MA Zurenski, ZM Parker, F Full, GJ Baumgart, ... Nature microbiology 2 (11), 1543-1557, 2017 | 195 | 2017 |
| RIG-I-like receptor regulation in virus infection and immunity YK Chan, MU Gack Current opinion in virology 12, 7-14, 2015 | 185 | 2015 |
| Inhibition of interferon regulatory factor 7 (IRF7)-mediated interferon signal transduction by the Kaposi's sarcoma-associated herpesvirus viral IRF homolog vIRF3 CH Joo, YC Shin, M Gack, L Wu, D Levy, JU Jung Journal of virology 81 (15), 8282-8292, 2007 | 171 | 2007 |
