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Aditya Raguram
Aditya Raguram
Whitehead Institute for Biomedical Research
Verified email at wi.mit.edu - Homepage
Title
Cited by
Cited by
Year
Search-and-replace genome editing without double-strand breaks or donor DNA
AV Anzalone, PB Randolph, JR Davis, AA Sousa, LW Koblan, JM Levy, ...
Nature 576 (7785), 149-157, 2019
41072019
Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction
LW Koblan, JL Doman, C Wilson, JM Levy, T Tay, GA Newby, JP Maianti, ...
Nature Biotechnology 36 (9), 843-846, 2018
9192018
Prime genome editing in rice and wheat
Q Lin*, Y Zong*, C Xue*, S Wang, S Jin, Z Zhu, Y Wang, AV Anzalone, ...
Nature Biotechnology 38 (5), 582-585, 2020
7592020
A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing
BY Mok*, MH de Moraes*, J Zeng, DE Bosch, AV Kotrys, A Raguram, ...
Nature 583 (7817), 631-637, 2020
6042020
Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins
S Banskota*, A Raguram*, S Suh, SW Du, JR Davis, EH Choi, X Wang, ...
Cell 185 (2), 250–265, 2022
4022022
Evaluation and minimization of Cas9-independent off-target DNA editing by cytosine base editors
JL Doman*, A Raguram*, GA Newby, DR Liu
Nature Biotechnology 38 (5), 620-628, 2020
3992020
Programmable deletion, replacement, integration and inversion of large DNA sequences with twin prime editing
AV Anzalone*, XD Gao*, CJ Podracky*, AT Nelson, LW Koblan, ...
Nature Biotechnology 40, 731-740, 2022
3982022
Therapeutic in vivo delivery of gene editing agents
A Raguram*, S Banskota*, DR Liu
Cell 185 (15), 2806–2827, 2022
2712022
CRISPR-free base editors with enhanced activity and expanded targeting scope in mitochondrial and nuclear DNA
BY Mok, AV Kotrys, A Raguram, TP Huang, VK Mootha, DR Liu
Nature Biotechnology 40, 1378-1387, 2022
1412022
Evolution of an adenine base editor into a small, efficient cytosine base editor with low off-target activity
ME Neugebauer, A Hsu, M Arbab, NA Krasnow, AN McElroy, S Pandey, ...
Nature Biotechnology 41 (5), 673-685, 2023
1282023
Ribozyme-catalysed RNA synthesis using triplet building blocks
J Attwater, A Raguram, AS Morgunov, E Gianni, P Holliger
eLife 7, e35255, 2018
1272018
Phage-assisted evolution and protein engineering yield compact, efficient prime editors
JL Doman*, S Pandey*, ME Neugebauer, M An, JR Davis, PB Randolph, ...
Cell 186 (18), 3983-4002. e26, 2023
1242023
Efficient in vivo base editing via single adeno-associated viruses with size-optimized genomes encoding compact adenine base editors
JR Davis, X Wang, IP Witte, TP Huang, JM Levy, A Raguram, S Banskota, ...
Nature Biomedical Engineering 6, 1272-1283, 2022
1232022
Efficient in vivo genome editing prevents hypertrophic cardiomyopathy in mice
D Reichart*, GA Newby*, H Wakimoto*, M Lun, JM Gorham, JJ Curran, ...
Nature Medicine 29, 412-421, 2023
1062023
Base editing rescue of spinal muscular atrophy in cells and in mice
M Arbab*, Z Matuszek*, KM Kray, A Du, GA Newby, AJ Blatnik, ...
Science, eadg6518, 2023
782023
Engineered virus-like particles for transient delivery of prime editor ribonucleoprotein complexes in vivo
M An, A Raguram, SW Du, S Banskota, JR Davis, GA Newby, PZ Chen, ...
Nature Biotechnology 42, 1526-1537, 2024
632024
In vivo base editing rescues cone photoreceptors in a mouse model of early-onset inherited retinal degeneration
EH Choi*, S Suh*, AT Foik, H Leinonen, GA Newby, XD Gao, S Banskota, ...
Nature Communications 13 (1), 1-14, 2022
542022
Rational engineering and characterization of an mAb that neutralizes Zika virus by targeting a mutationally constrained quaternary epitope
K Tharakaraman*, S Watanabe*, KR Chan, J Huan, V Subramanian, ...
Cell Host & Microbe 23 (5), 618-627. e6, 2018
342018
Precision genome editing in the eye
S Suh, EH Choi, A Raguram, DR Liu, K Palczewski
Proceedings of the National Academy of Sciences 119 (39), e2210104119, 2022
282022
Disulfide-compatible phage-assisted continuous evolution in the periplasmic space
MS Morrison, T Wang, A Raguram, C Hemez, DR Liu
Nature communications 12 (1), 5959, 2021
202021
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Articles 1–20