An insight into FDA approved antibody-drug conjugates for cancer therapy JTW Tong, PWR Harris, MA Brimble, I Kavianinia Molecules 26 (19), 5847, 2021 | 283 | 2021 |
Structural basis for receptor activity-modifying protein-dependent selective peptide recognition by a G protein-coupled receptor JM Booe, CS Walker, J Barwell, G Kuteyi, J Simms, MA Jamaluddin, ... Molecular cell 58 (6), 1040-1052, 2015 | 131 | 2015 |
A one-pot approach to neoglycopeptides using orthogonal native chemical ligation and click chemistry DJ Lee, K Mandal, PWR Harris, MA Brimble, SBH Kent Organic Letters 11 (22), 5270-5273, 2009 | 100 | 2009 |
Amylin analog pramlintide induces migraine‐like attacks in patients H Ghanizada, MAM Al‐Karagholi, CS Walker, N Arngrim, T Rees, ... Annals of neurology 89 (6), 1157-1171, 2021 | 89 | 2021 |
NKT cell-dependent glycolipid–peptide vaccines with potent anti-tumour activity RJ Anderson, BJ Compton, C Tang, A Authier-Hall, CM Hayman, ... Chemical science 6 (9), 5120-5127, 2015 | 80 | 2015 |
Direct peptide lipidation through thiol-ene coupling enables rapid synthesis and evaluation of self-adjuvanting vaccine candidates. TH Wright, AES Brooks, AJ Didsbury, GM Williams, PWR Harris, P Dunbar, ... Angewandte Chemie International Edition 52 (40), 2013 | 80 | 2013 |
Peripheral administration of a novel diketopiperazine, NNZ 2591, prevents brain injury and improves somatosensory-motor function following hypoxia–ischemia in adult rats J Guan, S Mathai, P Harris, JY Wen, R Zhang, M Brimble, P Gluckman Neuropharmacology 53 (6), 749-762, 2007 | 74 | 2007 |
Statistical affect detection in collaborative chat M Brooks, K Kuksenok, MK Torkildson, D Perry, JJ Robinson, TJ Scott, ... Proceedings of the 2013 conference on Computer supported cooperative work …, 2013 | 73 | 2013 |
Peptide lipidation–a synthetic strategy to afford peptide based therapeutics R Kowalczyk, PWR Harris, GM Williams, SH Yang, MA Brimble Peptides and peptide-based biomaterials and their biomedical applications …, 2017 | 71 | 2017 |
NNZ-2566: A Gly–Pro–Glu analogue with neuroprotective efficacy in a rat model of acute focal stroke MJ Bickerdike, GB Thomas, DC Batchelor, ES Sirimanne, W Leong, H Lin, ... Journal of the neurological sciences 278 (1-2), 85-90, 2009 | 71 | 2009 |
Supplementation of blackcurrant anthocyanins increased cyclic glycine-proline in the cerebrospinal fluid of Parkinson patients: Potential treatment to improve insulin-like … D Fan, Y Alamri, K Liu, M MacAskill, P Harris, M Brimble, ... Nutrients 10 (6), 714, 2018 | 67 | 2018 |
Synthesis of cyclic proline-containing peptides via ring-closing metathesis PWR Harris, MA Brimble, PD Gluckman Organic Letters 5 (11), 1847-1850, 2003 | 67 | 2003 |
Molecular signature for receptor engagement in the metabolic peptide hormone amylin RL Bower, L Yule, TA Rees, G Deganutti, ER Hendrikse, PWR Harris, ... ACS Pharmacology & Translational Science 1 (1), 32-49, 2018 | 66 | 2018 |
Characterizing the mode of action of extracellular Connexin43 channel blocking mimetic peptides in an in vitro ischemia injury model Y Kim, JM Griffin, PWR Harris, SHC Chan, LFB Nicholson, MA Brimble, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (2), 68-78, 2017 | 66 | 2017 |
The role for IGF-1-derived small neuropeptides as a therapeutic target for neurological disorders J Guan, P Harris, M Brimble, Y Lei, J Lu, Y Yang, AJ Gunn Expert opinion on therapeutic targets 19 (6), 785-793, 2015 | 65 | 2015 |
Enhancing the oral bioavailability of peptide drugs by using chemical modification and other approaches N Yin, MA Brimble, PWR Harris, J Wen Med. Chem 4 (12), 763-769, 2014 | 65 | 2014 |
An improved procedure for the preparation of aminomethyl polystyrene resin and its use in solid phase (peptide) synthesis PWR Harris, SH Yang, MA Brimble Tetrahedron letters 52 (45), 6024-6026, 2011 | 64 | 2011 |
Radiation damage and racemic protein crystallography reveal the unique structure of the GASA/snakin protein superfamily H Yeung, CJ Squire, Y Yosaatmadja, S Panjikar, G López, A Molina, ... Angewandte Chemie 128 (28), 8062-8065, 2016 | 63 | 2016 |
Photo-induced radical thiol–ene chemistry: a versatile toolbox for peptide-based drug design M Ahangarpour, I Kavianinia, PWR Harris, MA Brimble Chemical Society Reviews 50 (2), 898-944, 2021 | 60 | 2021 |
Total synthesis of the cyclic depsipeptide YM-280193, a platelet aggregation inhibitor H Kaur, PWR Harris, PJ Little, MA Brimble Organic letters 17 (3), 492-495, 2015 | 60 | 2015 |