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Christine A. Iacobuzio-Donahue
Christine A. Iacobuzio-Donahue
Verified email at mskcc.org - Homepage
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Year
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
S Jones, X Zhang, DW Parsons, JCH Lin, RJ Leary, P Angenendt, ...
science 321 (5897), 1801-1806, 2008
47732008
Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
KP Olive, MA Jacobetz, CJ Davidson, A Gopinathan, D McIntyre, ...
Science 324 (5933), 1457-1461, 2009
36472009
Genomic analyses identify molecular subtypes of pancreatic cancer
P Bailey, DK Chang, K Nones, AL Johns, AM Patch, MC Gingras, ...
Nature 531 (7592), 47-52, 2016
34982016
Distant metastasis occurs late during the genetic evolution of pancreatic cancer
S Yachida, S Jones, I Bozic, T Antal, R Leary, B Fu, M Kamiyama, ...
Nature 467 (7319), 1114-1117, 2010
29952010
Whole genomes redefine the mutational landscape of pancreatic cancer
N Waddell, M Pajic, AM Patch, DK Chang, KS Kassahn, P Bailey, ...
Nature 518 (7540), 495-501, 2015
28052015
Massive genomic rearrangement acquired in a single catastrophic event during cancer development
PJ Stephens, CD Greenman, B Fu, F Yang, GR Bignell, LJ Mudie, ...
cell 144 (1), 27-40, 2011
27212011
A draft map of the human proteome
MS Kim, SM Pinto, D Getnet, RS Nirujogi, SS Manda, R Chaerkady, ...
Nature 509 (7502), 575-581, 2014
25642014
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
GM DeNicola, FA Karreth, TJ Humpton, A Gopinathan, C Wei, K Frese, ...
Nature 475 (7354), 106-109, 2011
24162011
Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
AV Biankin, N Waddell, KS Kassahn, MC Gingras, LB Muthuswamy, ...
Nature 491 (7424), 399-405, 2012
22762012
Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma
AD Rhim, PE Oberstein, DH Thomas, ET Mirek, CF Palermo, SA Sastra, ...
Cancer cell 25 (6), 735-747, 2014
21452014
Organoid models of human and mouse ductal pancreatic cancer
SF Boj, CI Hwang, LA Baker, IIC Chio, DD Engle, V Corbo, M Jager, ...
Cell 160 (1), 324-338, 2015
21292015
Virtual microdissection identifies distinct tumor-and stroma-specific subtypes of pancreatic ductal adenocarcinoma
RA Moffitt, R Marayati, EL Flate, KE Volmar, SGH Loeza, KA Hoadley, ...
Nature genetics 47 (10), 1168-1178, 2015
19942015
Pan-cancer analysis of whole genomes
Nature 578 (7793), 82-93, 2020
1992*2020
The patterns and dynamics of genomic instability in metastatic pancreatic cancer
PJ Campbell, S Yachida, LJ Mudie, PJ Stephens, ED Pleasance, ...
Nature 467 (7319), 1109-1113, 2010
15952010
DPC4 Gene Status of the Primary Carcinoma Correlates With Patterns of Failure in Patients With Pancreatic Cancer
CA Iacobuzio-Donahue, B Fu, S Yachida, M Luo, H Abe, CM Henderson, ...
Journal of clinical oncology 27 (11), 1806-1813, 2009
12072009
Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer
VP Balachandran, M Łuksza, JN Zhao, V Makarov, JA Moral, R Remark, ...
Nature 551 (7681), 512-516, 2017
10882017
Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene
S Jones, RH Hruban, M Kamiyama, M Borges, X Zhang, DW Parsons, ...
Science 324 (5924), 217-217, 2009
10492009
Organoid profiling identifies common responders to chemotherapy in pancreatic cancer
H Tiriac, P Belleau, DD Engle, D Plenker, A Deschênes, TDD Somerville, ...
Cancer discovery 8 (9), 1112-1129, 2018
9442018
The genomic landscape of endocrine-resistant advanced breast cancers
P Razavi, MT Chang, G Xu, C Bandlamudi, DS Ross, N Vasan, Y Cai, ...
Cancer cell 34 (3), 427-438. e6, 2018
9022018
Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers
G Feldmann, S Dhara, V Fendrich, D Bedja, R Beaty, M Mullendore, ...
Cancer research 67 (5), 2187-2196, 2007
8602007
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