IL-11 is a crucial determinant of cardiovascular fibrosis S Schafer, S Viswanathan, AA Widjaja, WW Lim, A Moreno-Moral, ... Nature 552 (7683), 110-115, 2017 | 586 | 2017 |
Titin-truncating variants affect heart function in disease cohorts and the general population S Schafer, A De Marvao, E Adami, LR Fiedler, B Ng, E Khin, ... Nature genetics 49 (1), 46-53, 2017 | 323 | 2017 |
Interleukin-11 is a therapeutic target in idiopathic pulmonary fibrosis B Ng, J Dong, G D’Agostino, S Viswanathan, AA Widjaja, WW Lim, ... Science translational medicine 11 (511), eaaw1237, 2019 | 251 | 2019 |
Inhibiting interleukin 11 signaling reduces hepatocyte death and liver fibrosis, inflammation, and steatosis in mouse models of nonalcoholic steatohepatitis AA Widjaja, BK Singh, E Adami, S Viswanathan, J Dong, GA D’Agostino, ... Gastroenterology 157 (3), 777-792. e14, 2019 | 251 | 2019 |
Hepatocyte-specific IL11 cis-signaling drives lipotoxicity and underlies the transition from NAFLD to NASH J Dong, S Viswanathan, E Adami, BK Singh, SP Chothani, B Ng, WW Lim, ... Nature communications 12 (1), 66, 2021 | 105 | 2021 |
Molecular basis of immortalization of human mesenchymal stem cells by combination of p53 knockdown and human telomerase reverse transcriptase overexpression TM Liu, WM Ng, HS Tan, D Vinitha, Z Yang, JB Fan, Y Zou, JH Hui, ... Stem cells and development 22 (2), 268-278, 2013 | 97 | 2013 |
Interleukin-11 signaling underlies fibrosis, parenchymal dysfunction, and chronic inflammation of the airway B Ng, SA Cook, S Schafer Experimental & Molecular Medicine 52 (12), 1871-1878, 2020 | 83 | 2020 |
Interleukin-11 is important for vascular smooth muscle phenotypic switching and aortic inflammation, fibrosis and remodeling in mouse models WW Lim, B Corden, B Ng, K Vanezis, G D’Agostino, AA Widjaja, WH Song, ... Scientific reports 10 (1), 17853, 2020 | 59 | 2020 |
Fibroblast‐specific IL11 signaling drives chronic inflammation in murine fibrotic lung disease B Ng, J Dong, S Viswanathan, AA Widjaja, BS Paleja, E Adami, NSJ Ko, ... The FASEB Journal 34 (9), 11802-11815, 2020 | 58 | 2020 |
Transgenic interleukin 11 expression causes cross-tissue fibro-inflammation and an inflammatory bowel phenotype in mice WW Lim, B Ng, A Widjaja, C Xie, L Su, N Ko, SY Lim, XY Kwek, S Lim, ... PLoS One 15 (1), e0227505, 2020 | 57 | 2020 |
Redefining IL11 as a regeneration-limiting hepatotoxin and therapeutic target in acetaminophen-induced liver injury AA Widjaja, J Dong, E Adami, S Viswanathan, B Ng, LS Pakkiri, ... Science translational medicine 13 (597), eaba8146, 2021 | 55 | 2021 |
IL11 is elevated in systemic sclerosis and IL11-dependent ERK signalling underlies TGFβ-mediated activation of dermal fibroblasts E Adami, S Viswanathan, AA Widjaja, B Ng, S Chothani, N Zhihao, J Tan, ... Rheumatology 60 (12), 5820-5826, 2021 | 48 | 2021 |
Similarities and differences between IL11 and IL11RA1 knockout mice for lung fibro-inflammation, fertility and craniosynostosis B Ng, AA Widjaja, S Viswanathan, J Dong, SP Chothani, S Lim, ... Scientific Reports 11 (1), 14088, 2021 | 39 | 2021 |
Inhibition of IL11 signaling reduces aortic pathology in murine marfan syndrome WW Lim, J Dong, B Ng, AA Widjaja, C Xie, L Su, XY Kwek, NGZ Tee, ... Circulation Research 130 (5), 728-740, 2022 | 35 | 2022 |
Titin truncations lead to impaired cardiomyocyte autophagy and mitochondrial function in vivo J Zhou, B Ng, NSJ Ko, LR Fiedler, E Khin, A Lim, NE Sahib, Y Wu, ... Human molecular genetics 28 (12), 1971-1981, 2019 | 32 | 2019 |
Loss of protein kinase C-δ protects against LPS-induced osteolysis owing to an intrinsic defect in osteoclastic bone resorption EC Khor, T Abel, J Tickner, SM Chim, C Wang, T Cheng, B Ng, PY Ng, ... PloS one 8 (8), e70815, 2013 | 32 | 2013 |
IL11 activates pancreatic stellate cells and causes pancreatic inflammation, fibrosis and atrophy in a mouse model of pancreatitis B Ng, S Viswanathan, AA Widjaja, WW Lim, SG Shekeran, JWT Goh, ... International Journal of Molecular Sciences 23 (7), 3549, 2022 | 22 | 2022 |
Interleukin-11: a potential biomarker and molecular therapeutic target in non-small cell lung cancer JH Leung, B Ng, WW Lim Cells 11 (14), 2257, 2022 | 17 | 2022 |
Redefining Interleukin 11 as a regeneration-limiting hepatotoxin AA Widjaja, J Dong, E Adami, S Viswanathan, B Ng, BK Singh, WW Lim, ... bioRxiv, 830018, 2019 | 13 | 2019 |
Protein kinase C delta null mice exhibit structural alterations in articular surface, intra-articular and subchondral compartments X Yang, D Teguh, JP Wu, B He, TB Kirk, S Qin, S Li, H Chen, W Xue, B Ng, ... Arthritis Research & Therapy 17, 1-8, 2015 | 13 | 2015 |