Rho kinase (ROCK) inhibitors and their therapeutic potential Y Feng, PV LoGrasso, O Defert, R Li Journal of medicinal chemistry 59 (6), 2269-2300, 2016 | 421 | 2016 |
Acetyl-terminated and template-assembled collagen-based polypeptides composed of Gly-Pro-Hyp sequences. 2. Synthesis and conformational analysis by circular dichroism … Y Feng, G Melacini, JP Taulane, M Goodman Journal of the American Chemical Society 118 (43), 10351-10358, 1996 | 262 | 1996 |
A designed peptidomimetic agonistic ligand of TrkA nerve growth factor receptors S Maliartchouk, Y Feng, L Ivanisevic, T Debeir, AC Cuello, K Burgess, ... Molecular pharmacology 57 (2), 385-391, 2000 | 177 | 2000 |
Pharmacologic inhibition of ROCK2 suppresses amyloid-β production in an Alzheimer's disease mouse model JH Herskowitz, Y Feng, AL Mattheyses, CM Hales, LA Higginbotham, ... Journal of Neuroscience 33 (49), 19086-19098, 2013 | 163 | 2013 |
A Template-Induced Incipient Collagen-Like Triple-Helical Structure M Goodman, Y Feng, G Melacini, JP Taulane Journal of the American Chemical Society 118 (21), 5156-5157, 1996 | 129 | 1996 |
Benzimidazole-and benzoxazole-based inhibitors of Rho kinase EH Sessions, Y Yin, TD Bannister, A Weiser, E Griffin, J Pocas, ... Bioorganic & medicinal chemistry letters 18 (24), 6390-6393, 2008 | 111 | 2008 |
Development of highly selective casein kinase 1δ/1ε (CK1δ/ε) inhibitors with potent antiproliferative properties M Bibian, RJ Rahaim, JY Choi, Y Noguchi, S Schürer, W Chen, ... Bioorganic & medicinal chemistry letters 23 (15), 4374-4380, 2013 | 102 | 2013 |
Discovery of substituted 4-(pyrazol-4-yl)-phenylbenzodioxane-2-carboxamides as potent and highly selective Rho kinase (ROCK-II) inhibitors Y Feng, Y Yin, A Weiser, E Griffin, MD Cameron, L Lin, C Ruiz, ... Journal of medicinal chemistry 51 (21), 6642-6645, 2008 | 102 | 2008 |
Rho kinase inhibition as a therapeutic for progressive supranuclear palsy and corticobasal degeneration EG Gentry, BW Henderson, AE Arrant, M Gearing, Y Feng, NC Riddle, ... Journal of Neuroscience 36 (4), 1316-1323, 2016 | 95 | 2016 |
SNAr Cyclizations To Form Cyclic Peptidomimetics of β-Turns Y Feng, Z Wang, S Jin, K Burgess Journal of the American Chemical Society 120 (41), 10768-10769, 1998 | 92 | 1998 |
Collagen‐based structures containing the peptoid residue N‐isobutylglycine (Nleu): Synthesis and biophysical studies of Gly‐Pro‐Nleu sequences by circular dichroism … Y Feng, G Melacini, JP Taulane, M Goodman Biopolymers 39 (6), 859-872, 1996 | 90 | 1996 |
Rho kinase (ROCK) inhibitors and their application to inflammatory disorders PV LoGrasso, Y Feng Current topics in medicinal chemistry 9 (8), 704-723, 2009 | 88 | 2009 |
Collagen-like triple helices incorporating peptoid residues M Goodman, G Melacini, Y Feng Journal of the American Chemical Society 118 (44), 10928-10929, 1996 | 80 | 1996 |
Collagen-Based Structures Containing the Peptoid Residue N-Isobutylglycine (Nleu): Synthesis and Biophysical Studies of Gly-Nleu-Pro Sequences by Circular … Y Feng, G Melacini, M Goodman Biochemistry 36 (29), 8716-8724, 1997 | 76 | 1997 |
Solid-Phase SN2 Macrocyclization Reactions To Form β-Turn Mimics Y Feng, M Pattarawarapan, Z Wang, K Burgess Organic Letters 1 (1), 121-124, 1999 | 75 | 1999 |
Acetyl-Terminated and Template-Assembled Collagen-Based Polypeptides Composed of Gly-Pro-Hyp Sequences. 3. Conformational Analysis by 1H-NMR and … G Melacini, Y Feng, M Goodman Journal of the American Chemical Society 118 (43), 10359-10364, 1996 | 70 | 1996 |
Tetrahydroisoquinoline derivatives as highly selective and potent Rho kinase inhibitors X Fang, Y Yin, YT Chen, L Yao, B Wang, MD Cameron, L Lin, S Khan, ... Journal of medicinal chemistry 53 (15), 5727-5737, 2010 | 68 | 2010 |
Design and synthesis of highly potent and isoform selective JNK3 inhibitors: SAR studies on aminopyrazole derivatives K Zheng, S Iqbal, P Hernandez, HJ Park, PV LoGrasso, Y Feng Journal of medicinal chemistry 57 (23), 10013-10030, 2014 | 65 | 2014 |
Bis-aryl urea derivatives as potent and selective LIM kinase (Limk) inhibitors Y Yin, K Zheng, N Eid, S Howard, JH Jeong, F Yi, J Guo, CM Park, ... Journal of medicinal chemistry 58 (4), 1846-1861, 2015 | 62 | 2015 |
Collagen-Based Structures Containing the Peptoid Residue N-Isobutylglycine (Nleu). 6. Conformational Analysis of Gly-Pro-Nleu Sequences by 1H NMR, CD, and … G Melacini, Y Feng, M Goodman Journal of the American Chemical Society 118 (44), 10725-10732, 1996 | 60 | 1996 |