α-ketoglutarate orchestrates macrophage activation through metabolic and epigenetic reprogramming PS Liu, H Wang, X Li, T Chao, T Teav, S Christen, G Di Conza, WC Cheng, ... Nature immunology 18 (9), 985-994, 2017 | 872 | 2017 |
MET is required for the recruitment of anti-tumoural neutrophils V Finisguerra, G Di Conza, M Di Matteo, J Serneels, S Costa, ... Nature 522 (7556), 349-353, 2015 | 475 | 2015 |
Tumor hypoxia does not drive differentiation of tumor-associated macrophages but rather fine-tunes the M2-like macrophage population D Laoui, E Van Overmeire, G Di Conza, C Aldeni, J Keirsse, Y Morias, ... Cancer research 74 (1), 24-30, 2014 | 448 | 2014 |
Tumor stroma: a complexity dictated by the hypoxic tumor microenvironment A Casazza, G Di Conza, M Wenes, V Finisguerra, S Deschoemaeker, ... Oncogene 33 (14), 1743-1754, 2014 | 292 | 2014 |
ER stress responses: an emerging modulator for innate immunity G Di Conza, PC Ho Cells 9 (3), 695, 2020 | 208 | 2020 |
Tumor-induced reshuffling of lipid composition on the endoplasmic reticulum membrane sustains macrophage survival and pro-tumorigenic activity G Di Conza, CH Tsai, H Gallart-Ayala, YR Yu, F Franco, L Zaffalon, X Xie, ... Nature immunology 22 (11), 1403-1415, 2021 | 123 | 2021 |
The mTOR and PP2A pathways regulate PHD2 phosphorylation to fine-tune HIF1α levels and colorectal cancer cell survival under hypoxia G Di Conza, ST Cafarello, S Loroch, D Mennerich, S Deschoemaeker, ... Cell reports 18 (7), 1699-1712, 2017 | 118 | 2017 |
MDM4 (MDMX) localizes at the mitochondria and facilitates the p53‐mediated intrinsic‐apoptotic pathway F Mancini, G Di Conza, M Pellegrino, C Rinaldo, A Prodosmo, S Giglio, ... The EMBO journal 28 (13), 1926-1939, 2009 | 98 | 2009 |
Analysis of human MDM4 variants in papillary thyroid carcinomas reveals new potential markers of cancer properties A Prodosmo, S Giglio, S Moretti, F Mancini, F Barbi, N Avenia, G Di Conza, ... Journal of Molecular Medicine 86, 585-596, 2008 | 67 | 2008 |
Loss of caveolin-1 in metastasis-associated macrophages drives lung metastatic growth through increased angiogenesis W Celus, G Di Conza, AI Oliveira, M Ehling, BM Costa, M Wenes, ... Cell reports 21 (10), 2842-2854, 2017 | 59 | 2017 |
PHD 1 regulates p53‐mediated colorectal cancer chemoresistance S Deschoemaeker, G Di Conza, S Lilla, R Martín‐Pérez, D Mennerich, ... EMBO Molecular Medicine 7 (10), 1350-1365, 2015 | 55 | 2015 |
Control of immune cell function by the unfolded protein response G Di Conza, PC Ho, JR Cubillos-Ruiz, SCC Huang Nature Reviews Immunology 23 (9), 546-562, 2023 | 49 | 2023 |
Puzzling over MDM4–p53 network F Mancini, G Di Conza, O Monti, A Macchiarulo, R Pellicciari, A Pontecorvi, ... The international journal of biochemistry & cell biology 42 (7), 1080-1083, 2010 | 39 | 2010 |
CD8+ T cell metabolic rewiring defined by scRNA-seq identifies a critical role of ASNS expression dynamics in T cell differentiation J Fernández-García, F Franco, P Sweta, AM Patricia, AA Pane, ... Article 41 (7), 111639, 2022 | 33 | 2022 |
B55α/PP2A limits endothelial cell apoptosis during vascular remodeling: a complementary approach to disrupt pathological vessels? M Ehling, W Celus, R Martín-Pérez, R Alba-Rovira, S Willox, D Ponti, ... Circulation research 127 (6), 707-723, 2020 | 33 | 2020 |
PHD2 targeting overcomes breast cancer cell death upon glucose starvation in a PP2A/B55α-mediated manner G Di Conza, ST Cafarello, X Zheng, Q Zhang, M Mazzone Cell Reports 18 (12), 2836-2844, 2017 | 33 | 2017 |
Lipid-loaded macrophages as new therapeutic target in cancer G Marelli, N Morina, F Portale, M Pandini, M Iovino, G Di Conza, PC Ho, ... Journal for Immunotherapy of Cancer 10 (7), 2022 | 29 | 2022 |
IGF-1R/MDM2 relationship confers enhanced sensitivity to RITA in Ewing sarcoma cells G Di Conza, M Buttarelli, O Monti, M Pellegrino, F Mancini, A Pontecorvi, ... Molecular cancer therapeutics 11 (6), 1247-1256, 2012 | 28 | 2012 |
MDM4 enhances p53 stability by promoting an active conformation of the protein upon DNA damage G Di Conza, F Mancini, M Buttarelli, A Pontecorvi, F Trimarchi, F Moretti Cell Cycle 11 (4), 749-760, 2012 | 23 | 2012 |
Regulation of MDM4 (MDMX) function by p76MDM2: a new facet in the control of p53 activity S Giglio, F Mancini, M Pellegrino, G Di Conza, E Puxeddu, A Sacchi, ... Oncogene 29 (44), 5935-5945, 2010 | 21 | 2010 |