Mechanisms for insulin resistance: common threads and missing links VT Samuel, GI Shulman Cell 148 (5), 852-871, 2012 | 2694 | 2012 |
Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease VT Samuel, ZX Liu, X Qu, BD Elder, S Bilz, D Befroy, AJ Romanelli, ... Journal of Biological Chemistry 279 (31), 32345-32353, 2004 | 1767 | 2004 |
The pathogenesis of insulin resistance: integrating signaling pathways and substrate flux VT Samuel, GI Shulman The Journal of clinical investigation 126 (1), 12-22, 2016 | 1580 | 2016 |
Lipid-induced insulin resistance: unravelling the mechanism VT Samuel, KF Petersen, GI Shulman The Lancet 375 (9733), 2267-2277, 2010 | 1517 | 2010 |
Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase AK Madiraju, DM Erion, Y Rahimi, XM Zhang, DT Braddock, RA Albright, ... Nature 510 (7506), 542-546, 2014 | 1442 | 2014 |
The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes RJ Perry, VT Samuel, KF Petersen, GI Shulman Nature 510 (7503), 84-91, 2014 | 1257 | 2014 |
Standard operating procedures for describing and performing metabolic tests of glucose homeostasis in mice JE Ayala, VT Samuel, GJ Morton, S Obici, CM Croniger, GI Shulman, ... Disease models & mechanisms 3 (9-10), 525-534, 2010 | 846 | 2010 |
Nonalcoholic fatty liver disease as a nexus of metabolic and hepatic diseases VT Samuel, GI Shulman Cell metabolism 27 (1), 22-41, 2018 | 689 | 2018 |
Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease N Kumashiro, DM Erion, D Zhang, M Kahn, SA Beddow, X Chu, CD Still, ... Proceedings of the National Academy of Sciences 108 (39), 16381-16385, 2011 | 686 | 2011 |
FGF19 as a postprandial, insulin-independent activator of hepatic protein and glycogen synthesis S Kir, SA Beddow, VT Samuel, P Miller, SF Previs, K Suino-Powell, HE Xu, ... Science 331 (6024), 1621-1624, 2011 | 686 | 2011 |
Obesity, adiposity, and dyslipidemia: a consensus statement from the National Lipid Association HE Bays, PP Toth, PM Kris-Etherton, N Abate, LJ Aronne, WV Brown, ... Journal of clinical lipidology 7 (4), 304-383, 2013 | 682 | 2013 |
Inhibition of protein kinase Cε prevents hepatic insulin resistance in nonalcoholic fatty liver disease VT Samuel, ZX Liu, A Wang, SA Beddow, JG Geisler, M Kahn, X Zhang, ... The Journal of clinical investigation 117 (3), 739-745, 2007 | 625 | 2007 |
Desnutrin/ATGL is regulated by AMPK and is required for a brown adipose phenotype M Ahmadian, MJ Abbott, T Tang, CSS Hudak, Y Kim, M Bruss, ... Cell metabolism 13 (6), 739-748, 2011 | 587 | 2011 |
Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2 DB Savage, CS Choi, VT Samuel, ZX Liu, D Zhang, A Wang, XM Zhang, ... The Journal of clinical investigation 116 (3), 817-824, 2006 | 538 | 2006 |
Suppression of diacylglycerol acyltransferase-2 (DGAT2), but not DGAT1, with antisense oligonucleotides reverses diet-induced hepatic steatosis and insulin resistance CS Choi, DB Savage, A Kulkarni, XX Yu, ZX Liu, K Morino, S Kim, ... Journal of Biological Chemistry 282 (31), 22678-22688, 2007 | 445 | 2007 |
A high-protein diet for reducing body fat: mechanisms and possible caveats DH Pesta, VT Samuel Nutrition & metabolism 11, 1-8, 2014 | 440 | 2014 |
Fructose induced lipogenesis: from sugar to fat to insulin resistance VT Samuel Trends in endocrinology & metabolism 22 (2), 60-65, 2011 | 381 | 2011 |
Targeted expression of catalase to mitochondria prevents age-associated reductions in mitochondrial function and insulin resistance HY Lee, CS Choi, AL Birkenfeld, TC Alves, FR Jornayvaz, MJ Jurczak, ... Cell metabolism 12 (6), 668-674, 2010 | 366 | 2010 |
Paradoxical effects of increased expression of PGC-1α on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism CS Choi, DE Befroy, R Codella, S Kim, RM Reznick, YJ Hwang, ZX Liu, ... Proceedings of the National Academy of Sciences 105 (50), 19926-19931, 2008 | 332 | 2008 |
O-GlcNAc transferase/host cell factor C1 complex regulates gluconeogenesis by modulating PGC-1α stability HB Ruan, X Han, MD Li, JP Singh, K Qian, S Azarhoush, L Zhao, ... Cell metabolism 16 (2), 226-237, 2012 | 325 | 2012 |