| Crystal structure of the human TβR2 ectodomain–TGF-β3 complex PJ Hart, S Deep, AB Taylor, Z Shu, CS Hinck, AP Hinck Nature structural biology 9 (3), 203-208, 2002 | 372 | 2002 |
| Structural biology and evolution of the TGF-β family AP Hinck, TD Mueller, TA Springer Cold Spring Harbor perspectives in biology 8 (12), a022103, 2016 | 367 | 2016 |
| Cooperative assembly of TGF-β superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding J Groppe, CS Hinck, P Samavarchi-Tehrani, C Zubieta, JP Schuermann, ... Molecular cell 29 (2), 157-168, 2008 | 346 | 2008 |
| Structural studies of the TGF-βs and their receptors–insights into evolution of the TGF-β superfamily AP Hinck FEBS letters 586 (14), 1860-1870, 2012 | 316 | 2012 |
| Structural basis of J cochaperone binding and regulation of Hsp70 J Jiang, EG Maes, AB Taylor, L Wang, AP Hinck, EM Lafer, R Sousa Molecular cell 28 (3), 422-433, 2007 | 275 | 2007 |
| Transforming Growth Factor β1: Three-Dimensional Structure in Solution and Comparison with the X-ray Structure of Transforming Growth Factor β2, AP Hinck, SJ Archer, SW Qian, AB Roberts, MB Sporn, JA Weatherbee, ... Biochemistry 35 (26), 8517-8534, 1996 | 258 | 1996 |
| A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells CJC Johnston, DJ Smyth, RB Kodali, MPJ White, Y Harcus, KJ Filbey, ... Nature communications 8 (1), 1741, 2017 | 210 | 2017 |
| Ternary complex of transforming growth factor-β1 reveals isoform-specific ligand recognition and receptor recruitment in the superfamily S Radaev, Z Zou, T Huang, EM Lafer, AP Hinck, PD Sun Journal of Biological Chemistry 285 (19), 14806-14814, 2010 | 187 | 2010 |
| TGF-β uses a novel mode of receptor activation to phosphorylate SMAD1/5 and induce epithelial-to-mesenchymal transition A Ramachandran, P Vizan, D Das, P Chakravarty, J Vogt, KW Rogers, ... Elife 7, e31756, 2018 | 174 | 2018 |
| Multiple-quantum line narrowing for measurement of H. alpha.-H. beta. J couplings in isotopically enriched proteins S Grzesiek, H Kuboniwa, AP Hinck, A Bax Journal of the American Chemical Society 117 (19), 5312-5315, 1995 | 172 | 1995 |
| Effects of amino acid substitutions on the pressure denaturation of staphylococcal nuclease as monitored by fluorescence and nuclear magnetic resonance spectroscopy CA Royer, AP Hinck, SN Loh, KE Prehoda, X Peng, J Jonas, JL Markley Biochemistry 32 (19), 5222-5232, 1993 | 171 | 1993 |
| Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED MJ De La Cruz, J Hattne, D Shi, P Seidler, J Rodriguez, FE Reyes, ... Nature methods 14 (4), 399-402, 2017 | 165 | 2017 |
| TGF‐β signalling is mediated by two autonomously functioning TβRI: TβRII pairs T Huang, L David, V Mendoza, Y Yang, M Villarreal, K De, LZ Sun, X Fang, ... The EMBO journal 30 (7), 1263-1276, 2011 | 157 | 2011 |
| Structural basis for potency differences between GDF8 and GDF11 RG Walker, M Czepnik, EJ Goebel, JC McCoy, A Vujic, M Cho, J Oh, ... BMC biology 15, 1-22, 2017 | 136 | 2017 |
| Solvent effects on the energetics of prolyl peptide bond isomerization ES Eberhardt, SN Loh, AP Hinck, RT Raines Journal of the American Chemical Society 114 (13), 5437-5439, 1992 | 134 | 1992 |
| Assembly of TβRI: TβRII: TGFβ ternary complex in vitro with receptor extracellular domains is cooperative and isoform-dependent JE Zúñiga, JC Groppe, Y Cui, CS Hinck, V Contreras-Shannon, ... Journal of molecular biology 354 (5), 1052-1068, 2005 | 114 | 2005 |
| Polycomb group targeting through different binding partners of RING1B C-terminal domain R Wang, AB Taylor, BZ Leal, LV Chadwell, U Ilangovan, AK Robinson, ... Structure 18 (8), 966-975, 2010 | 112 | 2010 |
| Schistosoma mansoni: TGF-β signaling pathways PT LoVerde, A Osman, A Hinck Experimental Parasitology 117 (3), 304-317, 2007 | 112 | 2007 |
| Three key residues underlie the differential affinity of the TGFβ isoforms for the TGFβ type II receptor G De Crescenzo, CS Hinck, Z Shu, J Zúñiga, J Yang, Y Tang, ... Journal of molecular biology 355 (1), 47-62, 2006 | 111 | 2006 |
| High resolution solution structure of ribosomal protein L11-C76, a helical protein with a flexible loop that becomes structured upon binding to RNA MA Markus, AP Hinck, S Huang, DE Draper, DA Torchia Nature structural biology 4 (1), 70-77, 1997 | 109 | 1997 |
John MarkleyProfessor of Biochemistry University of Wisconsin-MadisonVerified email at wisc.edu