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James K. Fields
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Structural basis of IL-1 family cytokine signaling
JK Fields, S Günther, EJ Sundberg
Frontiers in immunology 10, 1412, 2019
2912019
Hijacking antibody-induced CTLA-4 lysosomal degradation for safer and more effective cancer immunotherapy
Y Zhang, X Du, M Liu, F Tang, P Zhang, C Ai, JK Fields, EJ Sundberg, ...
Cell Research 29 (8), 609-627, 2019
1072019
The structure of PilA from Acinetobacter baumannii AB5075 suggests a mechanism for functional specialization in Acinetobacter type IV pili
LA Ronish, E Lillehoj, JK Fields, EJ Sundberg, KH Piepenbrink
Journal of Biological Chemistry 294 (1), 218-230, 2019
782019
The fungal natural product azaphilone-9 binds to HuR and inhibits HuR-RNA interaction in vitro
K Kaur, X Wu, JK Fields, DK Johnson, L Lan, M Pratt, AD Somoza, ...
PLoS One 12 (4), e0175471, 2017
542017
Molecular Basis of Broad Spectrum N-Glycan Specificity and Processing of Therapeutic IgG Monoclonal Antibodies by Endoglycosidase S2
EH Klontz, B Trastoy, D Deredge, JK Fields, C Li, J Orwenyo, A Marina, ...
ACS Central Science 5 (3), 524-538, 2019
342019
Structure and dynamics of an α-fucosidase reveal a mechanism for highly efficient IgG transfucosylation
EH Klontz, C Li, K Kihn, JK Fields, D Beckett, GA Snyder, PL Wintrode, ...
Nature Communications 11 (1), 6204, 2020
332020
Molecular basis of selective cytokine signaling inhibition by antibodies targeting a shared receptor
JK Fields, K Kihn, GS Birkedal, EH Klontz, K Sjöström, S Günther, ...
Frontiers in Immunology 12, 779100, 2021
202021
Structural basis of IL-1 family cytokine signaling. Front Immunol. 2019; 10: 1412
JK Fields, S Günther, EJ Sundberg
Epub 2019/07/10. https://doi. org/10.3389/fimmu. 2019.01412 PMID: 31281320, 2019
112019
Structural basis of IL-1 family cytokine signaling. Front. Immunol. 10, 1412
JK Fields, S Günther, EJ Sundberg
92019
Diverse modes of regulating methyltransferase activity by histone ubiquitination
JK Fields, CW Hicks, C Wolberger
Current Opinion in Structural Biology 82, 102649, 2023
52023
Antibodies targeting the shared cytokine receptor IL-1 receptor accessory protein invoke distinct mechanisms to block all cytokine signaling
JK Fields, EJ Gyllenbäck, M Bogacz, J Obi, GS Birkedal, K Sjöström, ...
Cell Reports 43 (5), 2024
32024
Lipid A mimetics BECC438 and BECC470 potentiate durable and balanced immune responses using an ovalbumin murine vaccine model.
EM Harberts, DJ Varisco, JK Fields, JR Izac, FM Gardner, EJ Sundberg, ...
The Journal of Immunology 206 (1_Supplement), 59.02-59.02, 2021
22021
Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch
CW Hicks, S Rahman, SL Gloor, JK Fields, NL Husby, A Vaidya, KE Maier, ...
Nucleic Acids Research 52 (16), 9978-9995, 2024
2024
Combinatorially restricted computational design of protein-protein interfaces to produce IgG heterodimers
T Azzam, JJ Du, MW Flowers, AV Ali, JC Hunn, N Vijayvargiya, ...
Science Advances 10 (15), eadk8157, 2024
2024
Structural Dynamics of the Dengue Virus Non-structural 5 (NS5) Interactions with Promoter Stem Loop A (SLA)
JO Obi, KC Kihn, L McQueen, JK Fields, GA Snyder, DJ Deredge
bioRxiv, 2024.12. 03.626708, 2024
2024
The SAGA HAT module is tethered by its SWIRM domain and modulates activity of the SAGA DUB module
ST Haile, S Rahman, JK Fields, BC Orsburn, NN Bumpus, C Wolberger
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1866 (2), 194929, 2023
2023
Insights into the Binding of the Dengue Virus Nonstructural 5 (NS5) Protein to Stem Loop A (SLA)
J Obi, J Fields, L McQueen, D Deredge
The FASEB Journal 36, 2022
2022
Insights into the structural dynamics and RNA binding of the dengue nonstructural 5 (NS5) protein
JO Obi, JK Fields, DJ Deredge
Biophysical Journal 121 (3), 454a, 2022
2022
Hijacking antibody-induced CTLA-4 lysosomal degradation for safer and more effective cancer immunotherapy.
Y Zhang, X Du, M Liu, F Tang, P Zhang, C Ai, JK Fields, EJ Sundberg, ...
CANCER IMMUNOLOGY RESEARCH 8 (3), 87-87, 2020
2020
Abstract B3: Hijacking antibody-induced CTLA-4 lysosomal degradation for safer and more effective cancer immunotherapy
Y Zhang, X Du, M Liu, F Tang, P Zhang, C Ai, JK Fields, EJ Sundberg, ...
Cancer Immunology Research 8 (3_Supplement), B3-B3, 2020
2020
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