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Chong Ou
Chong Ou
Verified email at regeneron.com
Title
Cited by
Cited by
Year
Silane-Functionalized N-Heterocyclic Carbene–Cobalt Complexes Containing a Five-Coordinate Silicon with a Covalent Co–Si Bond
J Sun, C Ou, C Wang, M Uchiyama, L Deng
Organometallics 34 (8), 1546-1551, 2015
382015
General and Robust Chemoenzymatic Method for Glycan-Mediated Site-Specific Labeling and Conjugation of Antibodies: Facile Synthesis of Homogeneous Antibody–Drug Conjugates
X Zhang, C Ou, H Liu, SK Prabhu, C Li, Q Yang, LX Wang
ACS chemical biology 16 (11), 2502-2514, 2021
372021
Site-specific chemoenzymatic conjugation of high-affinity M6P glycan ligands to antibodies for targeted protein degradation
X Zhang, H Liu, J He, C Ou, TC Donahue, MM Muthana, L Su, LX Wang
ACS chemical biology 17 (11), 3013-3023, 2022
292022
One-Pot Conversion of Free Sialoglycans to Functionalized Glycan Oxazolines and Efficient Synthesis of Homogeneous Antibody–Drug Conjugates through Site-Specific Chemoenzymatic …
C Ou, C Li, R Zhang, Q Yang, G Zong, Y Dai, RL Francis, S Bournazos, ...
Bioconjugate chemistry 32 (8), 1888-1897, 2021
262021
Synthetic Antibody‐Rhamnose Cluster Conjugates Show Potent Complement‐Dependent Cell Killing by Recruiting Natural Antibodies
C Ou, SK Prabhu, X Zhang, G Zong, Q Yang, LX Wang
Chemistry–A European Journal 28 (16), e202200146, 2022
172022
Synthesis and evaluation of three azide-modified disaccharide oxazolines as enzyme substrates for single-step fc glycan-mediated antibody-drug conjugation
X Zhang, C Ou, H Liu, LX Wang
Bioconjugate chemistry 33 (6), 1179-1191, 2022
142022
Synthetic site-specific antibody–ligand conjugates promote asialoglycoprotein receptor-mediated degradation of extracellular human PCSK9
TC Donahue, C Ou, Q Yang, R Flinko, X Zhang, G Zong, GK Lewis, ...
ACS Chemical Biology 18 (7), 1611-1623, 2023
132023
Immunoglobulin G subclasses confer protection against Staphylococcus aureus bloodstream dissemination through distinct mechanisms in mouse models
X Chen, H Gula, T Pius, C Ou, M Gomozkova, LX Wang, O Schneewind, ...
Proceedings of the National Academy of Sciences 120 (14), e2220765120, 2023
82023
Synthesis and immunological study of N-Glycan-Bacteriophage Qβ conjugates reveal dominant antibody responses to the conserved chitobiose core
TC Donahue, G Zong, NA O’Brien, C Ou, JC Gildersleeve, LX Wang
Bioconjugate chemistry 33 (7), 1350-1362, 2022
72022
Catanionic vesicles as a facile scaffold to display natural n-glycan ligands for probing multivalent carbohydrate–lectin interactions
TC Donahue, G Zong, C Ou, P DeShong, LX Wang
Bioconjugate chemistry 34 (2), 392-404, 2023
52023
Synthesis, binding affinity, and inhibitory capacity of cyclodextrin-based multivalent glycan ligands for human galectin-3
C Ou, C Li, C Feng, X Tong, GR Vasta, LX Wang
Bioorganic & medicinal chemistry 72, 116974, 2022
42022
Evaluation of Two Chemoenzymatic Glycan Remodeling Approaches to Generate Site-Specific Antibody–Drug Conjugates
Q Yang, H Chen, C Ou, Z Zheng, X Zhang, Y Liu, G Zong, LX Wang
Antibodies 12 (4), 71, 2023
12023
A facile synthesis of a complex type N-glycan thiazoline as an effective inhibitor against the antibody-deactivating endo-β-N-acetylglucosaminidases
C Li, S Zhu, X Tong, C Ou, LX Wang
Journal of carbohydrate chemistry 36 (8-9), 336-346, 2017
12017
Chemoenzymatic Fc Glycan Engineering for Improving Antibody Immunotherapy
C Ou
University of Maryland, College Park, 2022
2022
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