Silane-Functionalized N-Heterocyclic Carbene–Cobalt Complexes Containing a Five-Coordinate Silicon with a Covalent Co–Si Bond J Sun, C Ou, C Wang, M Uchiyama, L Deng Organometallics 34 (8), 1546-1551, 2015 | 38 | 2015 |
General and Robust Chemoenzymatic Method for Glycan-Mediated Site-Specific Labeling and Conjugation of Antibodies: Facile Synthesis of Homogeneous Antibody–Drug Conjugates X Zhang, C Ou, H Liu, SK Prabhu, C Li, Q Yang, LX Wang ACS chemical biology 16 (11), 2502-2514, 2021 | 37 | 2021 |
Site-specific chemoenzymatic conjugation of high-affinity M6P glycan ligands to antibodies for targeted protein degradation X Zhang, H Liu, J He, C Ou, TC Donahue, MM Muthana, L Su, LX Wang ACS chemical biology 17 (11), 3013-3023, 2022 | 29 | 2022 |
One-Pot Conversion of Free Sialoglycans to Functionalized Glycan Oxazolines and Efficient Synthesis of Homogeneous Antibody–Drug Conjugates through Site-Specific Chemoenzymatic … C Ou, C Li, R Zhang, Q Yang, G Zong, Y Dai, RL Francis, S Bournazos, ... Bioconjugate chemistry 32 (8), 1888-1897, 2021 | 26 | 2021 |
Synthetic Antibody‐Rhamnose Cluster Conjugates Show Potent Complement‐Dependent Cell Killing by Recruiting Natural Antibodies C Ou, SK Prabhu, X Zhang, G Zong, Q Yang, LX Wang Chemistry–A European Journal 28 (16), e202200146, 2022 | 17 | 2022 |
Synthesis and evaluation of three azide-modified disaccharide oxazolines as enzyme substrates for single-step fc glycan-mediated antibody-drug conjugation X Zhang, C Ou, H Liu, LX Wang Bioconjugate chemistry 33 (6), 1179-1191, 2022 | 14 | 2022 |
Synthetic site-specific antibody–ligand conjugates promote asialoglycoprotein receptor-mediated degradation of extracellular human PCSK9 TC Donahue, C Ou, Q Yang, R Flinko, X Zhang, G Zong, GK Lewis, ... ACS Chemical Biology 18 (7), 1611-1623, 2023 | 13 | 2023 |
Immunoglobulin G subclasses confer protection against Staphylococcus aureus bloodstream dissemination through distinct mechanisms in mouse models X Chen, H Gula, T Pius, C Ou, M Gomozkova, LX Wang, O Schneewind, ... Proceedings of the National Academy of Sciences 120 (14), e2220765120, 2023 | 8 | 2023 |
Synthesis and immunological study of N-Glycan-Bacteriophage Qβ conjugates reveal dominant antibody responses to the conserved chitobiose core TC Donahue, G Zong, NA O’Brien, C Ou, JC Gildersleeve, LX Wang Bioconjugate chemistry 33 (7), 1350-1362, 2022 | 7 | 2022 |
Catanionic vesicles as a facile scaffold to display natural n-glycan ligands for probing multivalent carbohydrate–lectin interactions TC Donahue, G Zong, C Ou, P DeShong, LX Wang Bioconjugate chemistry 34 (2), 392-404, 2023 | 5 | 2023 |
Synthesis, binding affinity, and inhibitory capacity of cyclodextrin-based multivalent glycan ligands for human galectin-3 C Ou, C Li, C Feng, X Tong, GR Vasta, LX Wang Bioorganic & medicinal chemistry 72, 116974, 2022 | 4 | 2022 |
Evaluation of Two Chemoenzymatic Glycan Remodeling Approaches to Generate Site-Specific Antibody–Drug Conjugates Q Yang, H Chen, C Ou, Z Zheng, X Zhang, Y Liu, G Zong, LX Wang Antibodies 12 (4), 71, 2023 | 1 | 2023 |
A facile synthesis of a complex type N-glycan thiazoline as an effective inhibitor against the antibody-deactivating endo-β-N-acetylglucosaminidases C Li, S Zhu, X Tong, C Ou, LX Wang Journal of carbohydrate chemistry 36 (8-9), 336-346, 2017 | 1 | 2017 |
Chemoenzymatic Fc Glycan Engineering for Improving Antibody Immunotherapy C Ou University of Maryland, College Park, 2022 | | 2022 |