| Identification of preexisting adaptive immunity to Cas9 proteins in humans CT Charlesworth, PS Deshpande, DP Dever, J Camarena, VT Lemgart, ... Nature medicine 25 (2), 249-254, 2019 | 1058 | 2019 |
| Highly efficient and marker-free genome editing of human pluripotent stem cells by CRISPR-Cas9 RNP and AAV6 donor-mediated homologous recombination RM Martin, K Ikeda, MK Cromer, N Uchida, T Nishimura, R Romano, ... Cell stem cell 24 (5), 821-828. e5, 2019 | 194 | 2019 |
| Identification of somatic mutations in parathyroid tumors using whole-exome sequencing MK Cromer, LF Starker, M Choi, R Udelsman, C Nelson-Williams, ... The Journal of Clinical Endocrinology & Metabolism 97 (9), E1774-E1781, 2012 | 161 | 2012 |
| Global transcriptional response to CRISPR/Cas9-AAV6-based genome editing in CD34+ hematopoietic stem and progenitor cells MK Cromer, S Vaidyanathan, DE Ryan, B Curry, AB Lucas, J Camarena, ... Molecular Therapy 26 (10), 2431-2442, 2018 | 124 | 2018 |
| Development of β-globin gene correction in human hematopoietic stem cells as a potential durable treatment for sickle cell disease A Lattanzi, J Camarena, P Lahiri, H Segal, W Srifa, CA Vakulskas, ... Science translational medicine 13 (598), eabf2444, 2021 | 122 | 2021 |
| Priming human repopulating hematopoietic stem and progenitor cells for Cas9/sgRNA gene targeting CT Charlesworth, J Camarena, MK Cromer, S Vaidyanathan, RO Bak, ... Molecular Therapy-Nucleic Acids 12, 89-104, 2018 | 106 | 2018 |
| Improving the safety of human pluripotent stem cell therapies using genome-edited orthogonal safeguards RM Martin, JL Fowler, MK Cromer, BJ Lesch, E Ponce, N Uchida, ... Nature communications 11 (1), 2713, 2020 | 93 | 2020 |
| Gene replacement of α-globin with β-globin restores hemoglobin balance in β-thalassemia-derived hematopoietic stem and progenitor cells MK Cromer, J Camarena, RM Martin, BJ Lesch, CA Vakulskas, NM Bode, ... Nature medicine 27 (4), 677-687, 2021 | 77 | 2021 |
| Neomorphic effects of recurrent somatic mutations in Yin Yang 1 in insulin-producing adenomas MK Cromer, M Choi, C Nelson-Williams, AL Fonseca, JW Kunstman, ... Proceedings of the National Academy of Sciences 112 (13), 4062-4067, 2015 | 75 | 2015 |
| High-efficiency transgene integration by homology-directed repair in human primary cells using DNA-PKcs inhibition S Selvaraj, WN Feist, S Viel, S Vaidyanathan, AM Dudek, M Gastou, ... Nature Biotechnology 42 (5), 731-744, 2024 | 43 | 2024 |
| Ultra-deep sequencing validates safety of CRISPR/Cas9 genome editing in human hematopoietic stem and progenitor cells MK Cromer, VV Barsan, E Jaeger, M Wang, JP Hampton, F Chen, ... Nature communications 13 (1), 4724, 2022 | 35 | 2022 |
| CRISPR nuclease off-target activity and mitigation strategies B Wienert, MK Cromer Frontiers in Genome Editing 4, 1050507, 2022 | 25 | 2022 |
| Comparative analysis of CRISPR off-target discovery tools following ex vivo editing of CD34+ hematopoietic stem and progenitor cells MK Cromer, KR Majeti, GR Rettig, K Murugan, GL Kurgan, NM Bode, ... Molecular Therapy 31 (4), 1074-1087, 2023 | 22* | 2023 |
| Lineage-tracing hematopoietic stem cell origins in vivo to efficiently make human HLF+ HOXA+ hematopoietic progenitors from pluripotent stem cells JL Fowler, SL Zheng, A Nguyen, A Chen, X Xiong, T Chai, JY Chen, ... Developmental Cell 59 (9), 1110-1131. e22, 2024 | 17 | 2024 |
| Improved genome editing through inhibition of FANCM and members of the BTR dissolvase complex G de Alencastro, F Puzzo, M Pavel-Dinu, F Zhang, S Pillay, K Majzoub, ... Molecular Therapy 29 (3), 1016-1027, 2021 | 12 | 2021 |
| Transient inhibition of 53BP1 increases the frequency of targeted integration in human hematopoietic stem and progenitor cells R Baik, MK Cromer, SE Glenn, CA Vakulskas, KO Chmielewski, ... Nature Communications 15 (1), 111, 2024 | 10 | 2024 |
| Enhancement of erythropoietic output by Cas9-mediated insertion of a natural variant in haematopoietic stem and progenitor cells SE Luna, J Camarena, JP Hampton, KR Majeti, CT Charlesworth, ... Nature Biomedical Engineering, 1-13, 2024 | 6* | 2024 |
| Dual α-globin-truncated erythropoietin receptor knockin restores hemoglobin production in α-thalassemia-derived erythroid cells SN Chu, E Soupene, D Sharma, R Sinha, T McCreary, B Hernandez, ... Cell Reports 44 (1), 2025 | 2* | 2025 |
| Engineering synthetic signaling receptors to enable erythropoietin-free erythropoiesis AP Shah, KR Majeti, FK Ekman, S Selvaraj, D Sharma, R Sinha, ... Nature Communications 16 (1), 1140, 2025 | | 2025 |
| DIFFERENTIAL PROLIFERATION OF HUMAN HEMATOPOIETIC STEM AND PROGENITOR CELLS USING TRUNCATED ERYTHROPOIETIN RECEPTORS MH Porteus, MK Cromer, J Camarena US Patent App. 18/700,219, 2024 | | 2024 |
Matthew PorteusProfessor of Pediatrics, Stanford UniversityVerified email at stanford.edu