| Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis C Vennin, VT Chin, SC Warren, MC Lucas, D Herrmann, A Magenau, ... Science translational medicine 9 (384), eaai8504, 2017 | 260 | 2017 |
| CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan C Vennin, P Mélénec, R Rouet, M Nobis, AS Cazet, KJ Murphy, ... Nature communications 10 (1), 3637, 2019 | 237 | 2019 |
| Cancer cell-autonomous TRAIL-R signaling promotes KRAS-driven cancer progression, invasion, and metastasis S von Karstedt, A Conti, M Nobis, A Montinaro, T Hartwig, J Lemke, ... Cancer cell 27 (4), 561-573, 2015 | 209 | 2015 |
| Interaction of p53 with the CCT complex promotes protein folding and wild-type p53 activity AG Trinidad, PAJ Muller, J Cuellar, M Klejnot, M Nobis, JM Valpuesta, ... Molecular cell 50 (6), 805-817, 2013 | 161 | 2013 |
| MMP-9 triggered self-assembly of doxorubicin nanofiber depots halts tumor growth D Kalafatovic, M Nobis, J Son, KI Anderson, RV Ulijn Biomaterials 98, 192-202, 2016 | 157 | 2016 |
| Intravital FLIM-FRET imaging reveals dasatinib-induced spatial control of src in pancreatic cancer M Nobis, EJ McGhee, JP Morton, JP Schwarz, SA Karim, J Quinn, ... Cancer research 73 (15), 4674-4686, 2013 | 137 | 2013 |
| Organotypic collagen I assay: a malleable platform to assess cell behaviour in a 3-dimensional context P Timpson, EJ Mcghee, Z Erami, M Nobis, JA Quinn, M Edward, ... Journal of visualized experiments: JoVE, 3089, 2011 | 133 | 2011 |
| Temporal profiling of the breast tumour microenvironment reveals collagen XII as a driver of metastasis M Papanicolaou, AL Parker, M Yam, EC Filipe, SZ Wu, JL Chitty, K Wyllie, ... Nature communications 13 (1), 4587, 2022 | 128 | 2022 |
| Nuclear F-actin counteracts nuclear deformation and promotes fork repair during replication stress N Lamm, MN Read, M Nobis, D Van Ly, SG Page, VP Masamsetti, ... Nature cell biology 22 (12), 1460-1470, 2020 | 116 | 2020 |
| MMP-9 triggered micelle-to-fibre transitions for slow release of doxorubicin D Kalafatovic, M Nobis, N Javid, PWJM Frederix, KI Anderson, ... Biomaterials science 3 (2), 246-249, 2015 | 99 | 2015 |
| The Rac-FRET mouse reveals tight spatiotemporal control of Rac activity in primary cells and tissues AKE Johnsson, Y Dai, M Nobis, MJ Baker, EJ McGhee, S Walker, ... Cell reports 6 (6), 1153-1164, 2014 | 99 | 2014 |
| MTOR signaling orchestrates stress-induced mutagenesis, facilitating adaptive evolution in cancer A Cipponi, DL Goode, J Bedo, MJ McCabe, M Pajic, DR Croucher, ... Science 368 (6495), 1127-1131, 2020 | 96 | 2020 |
| A RhoA-FRET biosensor mouse for intravital imaging in normal tissue homeostasis and disease contexts M Nobis, D Herrmann, SC Warren, S Kadir, W Leung, M Killen, ... Cell reports 21 (1), 274-288, 2017 | 96 | 2017 |
| Intravital FRAP imaging using an E-cadherin-GFP mouse reveals disease-and drug-dependent dynamic regulation of cell-cell junctions in live tissue Z Erami, D Herrmann, SC Warren, M Nobis, EJ McGhee, MC Lucas, ... Cell reports 14 (1), 152-167, 2016 | 71 | 2016 |
| Intravital imaging to monitor therapeutic response in moving hypoxic regions resistant to PI3K pathway targeting in pancreatic cancer JRW Conway, SC Warren, D Herrmann, KJ Murphy, AS Cazet, C Vennin, ... Cell reports 23 (11), 3312-3326, 2018 | 68 | 2018 |
| TGFβ pathway limits dedifferentiation following WNT and MAPK pathway activation to suppress intestinal tumourigenesis P Cammareri, DF Vincent, MC Hodder, RA Ridgway, C Murgia, M Nobis, ... Cell Death & Differentiation 24 (10), 1681-1693, 2017 | 59 | 2017 |
| Acute compressive stress activates RHO/ROCK-mediated cellular processes ST Boyle, J Kular, M Nobis, A Ruszkiewicz, P Timpson, MS Samuel Small GTPases 11 (5), 354-370, 2020 | 54 | 2020 |
| Removing physiological motion from intravital and clinical functional imaging data SC Warren, M Nobis, A Magenau, YH Mohammed, D Herrmann, I Moran, ... Elife 7, e35800, 2018 | 50 | 2018 |
| Peripheral-specific Y1 receptor antagonism increases thermogenesis and protects against diet-induced obesity C Yan, T Zeng, K Lee, M Nobis, K Loh, L Gou, Z Xia, Z Gao, M Bensellam, ... Nature communications 12 (1), 2622, 2021 | 49 | 2021 |
| Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer SP Kennedy, JZR Han, N Portman, M Nobis, JF Hastings, KJ Murphy, ... Breast Cancer Research 21, 1-17, 2019 | 46 | 2019 |
Ewan J McGheeBeatson Institute for Cancer ResearchVerified email at beatson.gla.ac.uk