CRISPR interference-based platform for multimodal genetic screens in human iPSC-derived neurons R Tian, MA Gachechiladze, CH Ludwig, MT Laurie, JY Hong, D Nathaniel, ... Neuron 104 (2), 239-255. e12, 2019 | 432 | 2019 |
Memory regulatory T cells reside in human skin RS Rodriguez, ML Pauli, IM Neuhaus, SY Siegrid, ST Arron, HW Harris, ... The Journal of clinical investigation 124 (3), 1027-1036, 2014 | 396 | 2014 |
Scalable production of iPSC-derived human neurons to identify tau-lowering compounds by high-content screening C Wang, ME Ward, R Chen, K Liu, TE Tracy, X Chen, M Xie, PD Sohn, ... Stem cell reports 9 (4), 1221-1233, 2017 | 329 | 2017 |
Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity YJ Zhang, L Guo, PK Gonzales, TF Gendron, Y Wu, K Jansen-West, ... Science 363 (6428), eaav2606, 2019 | 230 | 2019 |
Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis ME Ward, R Chen, HY Huang, C Ludwig, M Telpoukhovskaia, A Taubes, ... Science translational medicine 9 (385), eaah5642, 2017 | 195 | 2017 |
Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy FA Sayed, M Telpoukhovskaia, L Kodama, Y Li, Y Zhou, D Le, A Hauduc, ... Proceedings of the National Academy of Sciences 115 (40), 10172-10177, 2018 | 151 | 2018 |
Systematic three-dimensional coculture rapidly recapitulates interactions between human neurons and astrocytes R Krencik, K Seo, JV van Asperen, N Basu, C Cvetkovic, S Barlas, ... Stem cell reports 9 (6), 1745-1753, 2017 | 107 | 2017 |
Large-scale mapping and mutagenesis of human transcriptional effector domains N DelRosso, J Tycko, P Suzuki, C Andrews, Aradhana, A Mukund, ... Nature 616 (7956), 365-372, 2023 | 84 | 2023 |
Mapping chromatin modifications at the single cell level CH Ludwig, L Bintu, A Klein, B Treutlein Development 146 (12), 2019 | 60 | 2019 |
Dynamic spreading of chromatin-mediated gene silencing and reactivation between neighboring genes in single cells S Lensch, MH Herschl, CH Ludwig, J Sinha, MM Hinks, A Mukund, ... Elife 11, e75115, 2022 | 26 | 2022 |
High-throughput functional characterization of combinations of transcriptional activators and repressors AX Mukund, J Tycko, SJ Allen, SA Robinson, C Andrews, J Sinha, ... Cell Systems 14 (9), 746-763. e5, 2023 | 23 | 2023 |
High-throughput discovery and characterization of viral transcriptional effectors in human cells CH Ludwig, AR Thurm, DW Morgens, KJ Yang, J Tycko, MC Bassik, ... Cell Systems 14 (6), 482-500. e8, 2023 | 19 | 2023 |
Development of compact transcriptional effectors using high-throughput measurements in diverse contexts J Tycko, MV Van, Aradhana, N DelRosso, H Ye, D Yao, R Valbuena, ... Nature Biotechnology, 1-14, 2024 | 16 | 2024 |
The H3. 3K36M oncohistone disrupts the establishment of epigenetic memory through loss of DNA methylation J Sinha, JF Nickels, AR Thurm, CH Ludwig, BN Archibald, MM Hinks, ... Molecular Cell 84 (20), 3899-3915. e7, 2024 | 4 | 2024 |
iNeuron pre-differentiation & differentiation protocol M Chen, N Draeger, M Kampmann, K Leng, E Li, C Ludwig, G Mohl, ... | 2 | 2020 |
763 Developments in MRI and MRS for biological/functional imaging JR Griffiths, C Ludwig, DJO McIntyre EJC Supplements 5 (1), S229, 2003 | 1 | 2003 |
High-throughput development and characterization of new functional nanobodies for gene regulation and epigenetic control in human cells J Wan, AR Thurm, SJ Allen, CH Ludwig, AN Patel, LR Bintu bioRxiv, 2024.11. 01.621523, 2024 | | 2024 |
High-Throughput and Single-Cell Methods for Measuring Gene Expression and Chromatin Modification Changes Produced by Viral Proteins in Human Cells CH Ludwig Stanford University, 2023 | | 2023 |
WTc11 iPSC Culture and Maintenance C Ludwig, R Tian, M Kampmann | | 2019 |
A path through a crowd P Szuromi Science 363 (6428), 703-703, 2019 | | 2019 |