| Direct detection of early-stage cancers using circulating tumor DNA J Phallen, M Sausen, V Adleff, A Leal, C Hruban, J White, V Anagnostou, ... Science translational medicine 9 (403), eaan2415, 2017 | 1139 | 2017 |
| Genome-wide cell-free DNA fragmentation in patients with cancer S Cristiano, A Leal, J Phallen, J Fiksel, V Adleff, DC Bruhm, SØ Jensen, ... Nature 570 (7761), 385-389, 2019 | 1068 | 2019 |
| Detection and characterization of lung cancer using cell-free DNA fragmentomes D Mathios, JS Johansen, S Cristiano, JE Medina, J Phallen, KR Larsen, ... Nature communications 12 (1), 5060, 2021 | 326 | 2021 |
| Dynamics of tumor and immune responses during immune checkpoint blockade in non–small cell lung cancer V Anagnostou, PM Forde, JR White, N Niknafs, C Hruban, J Naidoo, ... Cancer research 79 (6), 1214-1225, 2019 | 293 | 2019 |
| White blood cell and cell-free DNA analyses for detection of residual disease in gastric cancer A Leal, NCT van Grieken, DN Palsgrove, J Phallen, JE Medina, C Hruban, ... Nature communications 11 (1), 525, 2020 | 227 | 2020 |
| Early noninvasive detection of response to targeted therapy in non–small cell lung cancer J Phallen, A Leal, BD Woodward, PM Forde, J Naidoo, KA Marrone, ... Cancer research 79 (6), 1204-1213, 2019 | 115 | 2019 |
| Impact of COVID-19 pandemic on care of oncological patients: experience of a cancer center in a Latin American pandemic epicenter SEA Araujo, A Leal, AFY Centrone, VD Teich, DT Malheiro, AS Cypriano, ... Einstein (Sao Paulo) 19, eAO6282, 2020 | 70 | 2020 |
| Phase I study of rapid alternation of sunitinib and regorafenib for the treatment of tyrosine kinase inhibitor refractory gastrointestinal stromal tumors C Serrano, A Leal, Y Kuang, JA Morgan, CM Barysauskas, J Phallen, ... Clinical Cancer Research 25 (24), 7287-7293, 2019 | 44 | 2019 |
| Impacto da COVID-19 sobre o atendimento de pacientes oncológicos: experiência de um centro oncológico localizado em um epicentro Latino-Americano da pandemia SEA Araujo, A Leal, AFY Centrone, VD Teich, DT Malheiro, AS Cypriano, ... Einstein (São Paulo) 19, eAO6282, 2020 | 34 | 2020 |
| Tissue and cell-free DNA-based epigenomic approaches for cancer detection A Leal, D Sidransky, M Brait Clinical chemistry 66 (1), 105-116, 2020 | 34 | 2020 |
| Metastatic colorectal cancer treatment response evaluation by ultra-deep sequencing of cell-free DNA and matched white blood cells I van't Erve, JE Medina, A Leal, E Papp, J Phallen, V Adleff, EJ Chiao, ... Clinical Cancer Research 29 (5), 899-909, 2023 | 27 | 2023 |
| Diagnostic strategies toward clinical implementation of liquid biopsy RAS/BRAF circulating tumor DNA analyses in patients with metastatic colorectal cancer I van't Erve, MJE Greuter, K Bolhuis, DCL Vessies, A Leal, GR Vink, ... The Journal of Molecular Diagnostics 22 (12), 1430-1437, 2020 | 25 | 2020 |
| KRAS A146 Mutations Are Associated With Distinct Clinical Behavior in Patients With Colorectal Liver Metastases I Van't Erve, NJ Wesdorp, JE Medina, L Ferreira, A Leal, J Huiskens, ... JCO precision oncology 5, 1758-1767, 2021 | 19 | 2021 |
| Gastric metastasis of breast cancer: a case series G dos Santos Fernandes, LD Batista Bugiato Faria, I de Assis Pereira, ... Rare Tumors 8 (3), 94-96, 2016 | 14 | 2016 |
| Metronomic chemotherapy in the neoadjuvant setting: results of two parallel feasibility trials (TraQme and TAME) in patients with HER2+ and HER2− locally advanced breast cancer V Petry, DM Gagliato, AIC Leal, RJ Arai, E Longo, F Andrade, MD Ricci, ... Brazilian Journal of Medical and Biological Research 48 (5), 479-485, 2015 | 14 | 2015 |
| Direct detection of early-stage cancers using circulating tumor DNA. Sci Transl Med. 2017; 9 (403) J Phallen, M Sausen, V Adleff, A Leal, C Hruban, J White, V Anagnostou, ... Epub 2017/08/18. https://doi. org/10.1126/scitranslmed. aan2415 PMID: 28814544, 0 | 14 | |
| Clinical validation of a cell-free DNA fragmentome assay for augmentation of lung cancer early detection PJ Mazzone, PB Bach, J Carey, CA Schonewolf, K Bognar, MS Ahluwalia, ... Cancer discovery 14 (11), 2224-2242, 2024 | 12 | 2024 |
| Applications of cell-free circulating tumor DNA detection in EGFR mutant lung cancer A Bulbul, A Leal, H Husain Journal of thoracic disease 12 (5), 2877, 2020 | 10 | 2020 |
| Elucidating the heterogeneity of immunotherapy response and immune-related toxicities by longitudinal ctDNA and immune cell compartment tracking in lung cancer JC Murray, L Sivapalan, K Hummelink, A Balan, JR White, N Niknafs, ... Clinical Cancer Research 30 (2), 389-403, 2024 | 9 | 2024 |
| Cell-free DNA fragmentomes in the diagnostic evaluation of patients with symptoms suggestive of lung cancer AIC Leal, D Mathios, D Jakubowski, JS Johansen, A Lau, T Wu, ... Chest 164 (4), 1019-1027, 2023 | 9 | 2023 |
Victor VelculescuProfessor of Oncology, Johns Hopkins University School of MedicineVerified email at jhmi.edu
