| Collagen degradation and MMP9 activation by Enterococcus faecalis contribute to intestinal anastomotic leak BD Shogan, N Belogortseva, PM Luong, A Zaborin, S Lax, C Bethel, ... Science translational medicine 7 (286), 286ra68-286ra68, 2015 | 406 | 2015 |
| Agent‐based models in translational systems biology G An, Q Mi, J Dutta‐Moscato, Y Vodovotz Wiley Interdisciplinary Reviews: Systems Biology and Medicine 1 (2), 159-171, 2009 | 401 | 2009 |
| Translational systems biology of inflammation Y Vodovotz, M Csete, J Bartels, S Chang, G An PLoS computational biology 4 (4), e1000014, 2008 | 270 | 2008 |
| In silico experiments of existing and hypothetical cytokine-directed clinical trials using agent-based modeling G An Critical care medicine 32 (10), 2050-2060, 2004 | 238 | 2004 |
| The Basic Immune Simulator: an agent-based model to study the interactions between innate and adaptive immunity VA Folcik, GC An, CG Orosz Theoretical Biology and Medical Modelling 4, 1-18, 2007 | 213 | 2007 |
| Intestinal Tissues Induce an SNP Mutation in Pseudomonas aeruginosa That Enhances Its Virulence: Possible Role in Anastomotic Leak AD Olivas, BD Shogan, V Valuckaite, A Zaborin, N Belogortseva, ... Public Library of Science 7 (8), e44326, 2012 | 196 | 2012 |
| Sepsis: Something old, something new, and a systems view R Namas, R Zamora, R Namas, G An, J Doyle, TE Dick, FJ Jacono, ... Journal of critical care 27 (3), 314. e1-314. e11, 2012 | 193 | 2012 |
| Abdominal compartment syndrome: a concise clinical review G An, MA West Critical care medicine 36 (4), 1304-1310, 2008 | 191 | 2008 |
| Toll-like receptor 2 ligands on the staphylococcal cell wall downregulate superantigen-induced T cell activation and prevent toxic shock syndrome TA Chau, ML McCully, W Brintnell, G An, KJ Kasper, ED Vinés, P Kubes, ... Nature medicine 15 (6), 641-648, 2009 | 170 | 2009 |
| Mechanistic simulations of inflammation: current state and future prospects Y Vodovotz, G Constantine, J Rubin, M Csete, EO Voit, G An Mathematical biosciences 217 (1), 1-10, 2009 | 169 | 2009 |
| Agent-based computer simulation and sirs: building a bridge between basic science and clinical trials G An Shock 16 (4), 266-273, 2001 | 166 | 2001 |
| Introduction of an agent-based multi-scale modular architecture for dynamic knowledge representation of acute inflammation G An Theoretical Biology and Medical Modelling 5, 1-20, 2008 | 153 | 2008 |
| Mathematical models of the acute inflammatory response Y Vodovotz, G Clermont, C Chow, G An Current opinion in critical care 10 (5), 383-390, 2004 | 153 | 2004 |
| Prospective evaluation of the sensitivity of physical examination in chest trauma F Bokhari, S Brakenridge, K Nagy, R Roberts, R Smith, K Joseph, G An, ... Journal of Trauma and Acute Care Surgery 53 (6), 1135-1138, 2002 | 144 | 2002 |
| Experience with over 2500 diagnostic peritoneal lavages KK Nagy, RR Roberts, KT Joseph, RF Smith, GC An, F Bokhari, J Barrett Injury 31 (7), 479-482, 2000 | 124 | 2000 |
| Evisceration after abdominal stab wounds: is laparotomy required? K Nagy, R Roberts, K Joseph, J Barrett Journal of Trauma and Acute Care Surgery 47 (4), 622, 1999 | 111 | 1999 |
| Building digital twins of the human immune system: toward a roadmap R Laubenbacher, A Niarakis, T Helikar, G An, B Shapiro, RS Malik-Sheriff, ... NPJ digital medicine 5 (1), 64, 2022 | 93 | 2022 |
| Translational systems approaches to the biology of inflammation and healing Y Vodovotz, G Constantine, J Faeder, Q Mi, J Rubin, J Bartels, J Sarkar, ... Immunopharmacology and immunotoxicology 32 (2), 181-195, 2010 | 93 | 2010 |
| Prognosis of penetrating trauma in elderly patients: a comparison with younger patients KK Nagy, RF Smith, RR Roberts, KT Joseph, GC An, F Bokhari, J Barrett Journal of Trauma and Acute Care Surgery 49 (2), 190-194, 2000 | 93 | 2000 |
| Optimization and control of agent-based models in biology: a perspective G An, BG Fitzpatrick, S Christley, P Federico, A Kanarek, RM Neilan, ... Bulletin of mathematical biology 79, 63-87, 2017 | 88 | 2017 |
Yoram VodovotzProfessor of Surgery, University of PittsburghVerified email at upmc.edu