Tissue curvature and apicobasal mechanical tension imbalance instruct cancer morphogenesis HA Messal, S Alt, RMM Ferreira, C Gribben, VMY Wang, CG Cotoi, ... Nature 566 (7742), 126-130, 2019 | 159 | 2019 |
Duct-and acinar-derived pancreatic ductal adenocarcinomas show distinct tumor progression and marker expression RMM Ferreira, R Sancho, HA Messal, E Nye, B Spencer-Dene, RK Stone, ... Cell reports 21 (4), 966-978, 2017 | 135 | 2017 |
Lgr6 labels a rare population of mammary gland progenitor cells that are able to originate luminal mammary tumours L Blaas, F Pucci, HA Messal, AB Andersson, E Josue Ruiz, M Gerling, ... Nature cell biology 18 (12), 1346-1356, 2016 | 91 | 2016 |
Antigen retrieval and clearing for whole-organ immunofluorescence by FLASH HA Messal, J Almagro, M Zaw Thin, A Tedeschi, A Ciccarelli, L Blackie, ... Nature protocols 16 (1), 239-262, 2021 | 88 | 2021 |
Ductal Ngn3-expressing progenitors contribute to adult β cell neogenesis in the pancreas C Gribben, C Lambert, HA Messal, EL Hubber, C Rackham, I Evans, ... Cell Stem Cell 28 (11), 2000-2008. e4, 2021 | 77 | 2021 |
Tissue clearing to examine tumour complexity in three dimensions J Almagro, HA Messal, M Zaw Thin, J van Rheenen, A Behrens Nature Reviews Cancer 21 (11), 718-730, 2021 | 70 | 2021 |
Tissue architecture in tumor initiation and progression J Almagro, HA Messal, A Elosegui-Artola, J van Rheenen, A Behrens Trends in Cancer 8 (6), 494-505, 2022 | 59 | 2022 |
Cep55 promotes cytokinesis of neural progenitors but is dispensable for most mammalian cell divisions A Tedeschi, J Almagro, MJ Renshaw, HA Messal, A Behrens, ... Nature communications 11 (1), 1746, 2020 | 52 | 2020 |
Retrograde movements determine effective stem cell numbers in the intestine M Azkanaz, B Corominas-Murtra, SIJ Ellenbroek, L Bruens, AT Webb, ... Nature 607 (7919), 548-554, 2022 | 50 | 2022 |
An intravital microscopy toolbox to study mammary gland dynamics from cellular level to organ scale HA Messal, J van Rheenen, CLGJ Scheele Journal of Mammary Gland Biology and Neoplasia 26 (1), 9-27, 2021 | 21 | 2021 |
Paligenosis: prepare to regenerate! HA Messal, CA Cremona, L Lan, A Behrens The EMBO Journal 37 (7), e99206, 2018 | 18 | 2018 |
A living biobank of patient-derived ductal carcinoma in situ mouse-intraductal xenografts identifies risk factors for invasive progression SJ Hutten, R de Bruijn, C Lutz, M Badoux, T Eijkman, X Chao, M Ciwinska, ... Cancer cell 41 (5), 986-1002. e9, 2023 | 16 | 2023 |
Mechanisms that clear mutations drive field cancerization in mammary tissue M Ciwinska, HA Messal, HR Hristova, C Lutz, L Bornes, T Chalkiadakis, ... Nature 633 (8028), 198-206, 2024 | 11 | 2024 |
Coordinated cancer chaos HA Messal, J van Rheenen Cell 186 (2), 235-237, 2023 | 7 | 2023 |
Rat models of hormone receptor-positive breast cancer R Nicotra, C Lutz, HA Messal, J Jonkers Journal of Mammary Gland Biology and Neoplasia 29 (1), 12, 2024 | 5 | 2024 |
Volume imaging to interrogate cancer cell-tumor microenvironment interactions in space and time J Almagro, HA Messal Frontiers in Immunology 14, 1176594, 2023 | 5 | 2023 |
BCRP drives intrinsic chemoresistance in chemotherapy-naïve breast cancer brain metastasis R Uceda-Castro, AS Margarido, JY Song, MC de Gooijer, HA Messal, ... Science advances 9 (42), eabp9530, 2023 | 4 | 2023 |
Heterogeneity-driven phenotypic plasticity and treatment response in branched-organoid models of pancreatic ductal adenocarcinoma A Papargyriou, M Najajreh, DP Cook, CH Maurer, S Bärthel, HA Messal, ... Nature biomedical engineering, 1-29, 2024 | 1 | 2024 |
Ductal carcinoma in situ develops within clonal fields of mutant cells in morphologically normal ducts SJ Hutten, HA Messal, EH Lips, M Sheinman, M Ciwinska, E Braams, ... The Journal of Pathology 263 (3), 360-371, 2024 | 1 | 2024 |
Laser Ablation and Intravital Microscopy to Study Intestinal Remodeling D Laskaris, M Azkanaz, MA de Vreij-Kruidenier, D van Rijswoud-Ram, ... JoVE (Journal of Visualized Experiments), e64756, 2023 | 1 | 2023 |