| Production of CFTR-null and CFTR-ΔF508 heterozygous pigs by adeno-associated virus–mediated gene targeting and somatic cell nuclear transfer CS Rogers, Y Hao, T Rokhlina, M Samuel, DA Stoltz, Y Li, E Petroff, ... The Journal of clinical investigation 118 (4), 1571-1577, 2008 | 516 | 2008 |
| Endosomal processing limits gene transfer to polarized airway epithelia by adeno-associated virus D Duan, Y Yue, Z Yan, J Yang, JF Engelhardt The Journal of clinical investigation 105 (11), 1573-1587, 2000 | 488 | 2000 |
| Disease phenotype of a ferret CFTR-knockout model of cystic fibrosis X Sun, H Sui, JT Fisher, Z Yan, X Liu, HJ Cho, NS Joo, Y Zhang, W Zhou, ... The Journal of clinical investigation 120 (9), 3149-3160, 2010 | 422 | 2010 |
| Trans-splicing vectors expand the utility of adeno-associated virus for gene therapy Z Yan, Y Zhang, D Duan, JF Engelhardt Proceedings of the National Academy of Sciences 97 (12), 6716-6721, 2000 | 394 | 2000 |
| Intracellular trafficking of adeno-associated viral vectors W Ding, L Zhang, Z Yan, JF Engelhardt Gene therapy 12 (11), 873-880, 2005 | 350 | 2005 |
| Ubiquitination of both adeno-associated virus type 2 and 5 capsid proteins affects the transduction efficiency of recombinant vectors Z Yan, R Zak, GWG Luxton, TC Ritchie, U Bantel-Schaal, JF Engelhardt Journal of virology 76 (5), 2043-2053, 2002 | 306 | 2002 |
| Virus-mediated transduction of murine retina with adeno-associated virus: effects of viral capsid and genome size GS Yang, M Schmidt, Z Yan, JD Lindbloom, TC Harding, BA Donahue, ... Journal of virology 76 (15), 7651-7660, 2002 | 263 | 2002 |
| A new dual-vector approach to enhance recombinant adeno-associated virus-mediated gene expression through intermolecular cis activation D Duan, Y Yue, Z Yan, JF Engelhardt Nature medicine 6 (5), 595-598, 2000 | 248 | 2000 |
| Polarity influences the efficiency of recombinant adenoassociated virus infection in differentiated airway epithelia D Duan, Y Yue, Z Yan, PB McCray Jr, JF Engelhardt Human gene therapy 9 (18), 2761-2776, 1998 | 245 | 1998 |
| Adeno-associated virus (AAV) serotypes have distinctive interactions with domains of the cellular AAV receptor S Pillay, W Zou, F Cheng, AS Puschnik, NL Meyer, SS Ganaie, X Deng, ... Journal of virology 91 (18), 10.1128/jvi. 00391-17, 2017 | 215 | 2017 |
| Establishment of a reverse genetics system for studying human bocavirus in human airway epithelia Q Huang, X Deng, Z Yan, F Cheng, Y Luo, W Shen, DCM Lei-Butters, ... Public Library of Science 8 (8), e1002899, 2012 | 197 | 2012 |
| Distinct classes of proteasome-modulating agents cooperatively augment recombinant adeno-associated virus type 2 and type 5-mediated transduction from the apical surfaces of … Z Yan, R Zak, Y Zhang, W Ding, S Godwin, K Munson, R Peluso, ... Journal of virology 78 (6), 2863-2874, 2004 | 184 | 2004 |
| Adeno-associated virus–targeted disruption of the CFTR gene in cloned ferrets X Sun, Z Yan, Y Yi, Z Li, D Lei, CS Rogers, J Chen, Y Zhang, MJ Welsh, ... The Journal of clinical investigation 118 (4), 1578-1583, 2008 | 173 | 2008 |
| Aspm knockout ferret reveals an evolutionary mechanism governing cerebral cortical size MB Johnson, X Sun, A Kodani, R Borges-Monroy, KM Girskis, SC Ryu, ... Nature 556 (7701), 370-375, 2018 | 161 | 2018 |
| In utero and postnatal VX-770 administration rescues multiorgan disease in a ferret model of cystic fibrosis X Sun, Y Yi, Z Yan, BH Rosen, B Liang, MC Winter, TIA Evans, PG Rotti, ... Science translational medicine 11 (485), eaau7531, 2019 | 160 | 2019 |
| Inverted terminal repeat sequences are important for intermolecular recombination and circularization of adeno-associated virus genomes Z Yan, R Zak, Y Zhang, JF Engelhardt Journal of virology 79 (1), 364-379, 2005 | 157 | 2005 |
| Abnormal endocrine pancreas function at birth in cystic fibrosis ferrets AK Olivier, Y Yi, X Sun, H Sui, B Liang, S Hu, W Xie, JT Fisher, NW Keiser, ... The Journal of clinical investigation 122 (10), 3755-3768, 2012 | 147 | 2012 |
| Structural analysis of adeno-associated virus transduction circular intermediates D Duan, Z Yan, Y Yue, JF Engelhardt Virology 261 (1), 8-14, 1999 | 144 | 1999 |
| Lung phenotype of juvenile and adult cystic fibrosis transmembrane conductance regulator–knockout ferrets X Sun, AK Olivier, B Liang, Y Yi, H Sui, TIA Evans, Y Zhang, W Zhou, ... American journal of respiratory cell and molecular biology 50 (3), 502-512, 2014 | 134 | 2014 |
| CFTR gene transfer with AAV improves early cystic fibrosis pig phenotypes B Steines, DD Dickey, J Bergen, KJDA Excoffon, JR Weinstein, X Li, ... JCI insight 1 (14), e88728, 2016 | 130 | 2016 |