Design, synthesis and anticancer evaluation of 1H-pyrazolo [3, 4-d] pyrimidine derivatives as potent EGFRWT and EGFRT790M inhibitors and apoptosis inducers AA Gaber, AH Bayoumi, AM El-Morsy, FF Sherbiny, ABM Mehany, ... Bioorganic chemistry 80, 375-395, 2018 | 126 | 2018 |
Synthesis, characterization and molecular docking studies of thiouracil derivatives as potent thymidylate synthase inhibitors and potential anticancer agents AM El-Naggar, MM Abou-El-Regal, SA El-Metwally, FF Sherbiny, IH Eissa Molecular diversity 21 (4), 967-983, 2017 | 75 | 2017 |
Design, synthesis, molecular modeling and biological evaluation of novel 2, 3-dihydrophthalazine-1, 4-dione derivatives as potential anticonvulsant agents AGA El-Helby, RR Ayyad, HM Sakr, AS Abdelrahim, K El-Adl, FS Sherbiny, ... Journal of Molecular Structure 1130, 333-351, 2017 | 69 | 2017 |
Ligand-Specific Binding and Activation of the Human Adenosine A2B Receptor D Thimm, AC Schiedel, FF Sherbiny, S Hinz, K Hochheiser, ... Biochemistry 52 (4), 726-740, 2013 | 60 | 2013 |
The second extracellular loop of GPCRs determines subtype-selectivity and controls efficacy as evidenced by loop exchange study at A2 adenosine receptors BF Seibt, AC Schiedel, D Thimm, S Hinz, FF Sherbiny, CE Müller Biochemical pharmacology 85 (9), 1317-1329, 2013 | 59 | 2013 |
Unravelling the anticancer potency of 1,2,4-triazole-N-arylamide hybrids through inhibition of STAT3: synthesis and in silico mechanistic studies A Turky, AH Bayoumi, FF Sherbiny, K El-Adl, HS Abulkhair Molecular diversity 25, 403-420, 2021 | 51 | 2021 |
Homology modelling of the human adenosine A 2B receptor based on X-ray structures of bovine rhodopsin, the β 2-adrenergic receptor and the human adenosine A 2A receptor FF Sherbiny, AC Schiedel, A Maaß, CE Müller Journal of computer-aided molecular design 23, 807-828, 2009 | 51 | 2009 |
Pharmacophore‐linked pyrazolo[3,4‐d]pyrimidines as EGFR‐TK inhibitors: Synthesis, anticancer evaluation, pharmacokinetics, and in silico mechanistic studies AA Gaber, AM El‐Morsy, FF Sherbiny, AH Bayoumi, KM El‐Gamal, ... Archiv Der Pharmazie, e2100258, 2021 | 48 | 2021 |
Hydrazone-based materials; DFT, TD-DFT, NBO analysis, fukui function, MESP analysis, and solar cell applications MAS Sakr, FF Sherbiny, AAS El-Etrawy Journal of Fluorescence 32 (5), 1857-1871, 2022 | 47 | 2022 |
The four cysteine residues in the second extracellular loop of the human adenosine A2B receptor: role in ligand binding and receptor function AC Schiedel, S Hinz, D Thimm, F Sherbiny, T Borrmann, A Maaß, ... Biochemical pharmacology 82 (4), 389-399, 2011 | 47 | 2011 |
Design, synthesis, and molecular docking studies of new [1,2,4]triazolo[4,3-a]quinoxaline derivatives as potential A2B receptor antagonists HG Ezzat, AH Bayoumi, FF Sherbiny, AM El-Morsy, A Ghiaty, M Alswah, ... Molecular Diversity 25, 291-306, 2021 | 37 | 2021 |
Novel 1, 2, 4‐triazole derivatives: Design, synthesis, anticancer evaluation, molecular docking, and pharmacokinetic profiling studies A Turky, FF Sherbiny, AH Bayoumi, HEA Ahmed, HS Abulkhair Archiv der Pharmazie 353 (12), 2000170, 2020 | 37 | 2020 |
Design, synthesis, biological evaluation and molecular modeling investigation of new N'-(2-Thiouracil-5-oyl) hydrazone derivatives as potential anti-breast cancer and anti … AAS El-Etrawy, FF Sherbiny Journal of Molecular Structure 1232, 129993, 2021 | 30 | 2021 |
Antimicrobial screening and pharmacokinetic profiling of novel phenyl-[1, 2, 4] triazolo [4, 3-a] quinoxaline analogues targeting DHFR and E. coli DNA gyrase B AM Omar, M Alswah, HEA Ahmed, AH Bayoumi, KM El-Gamal, A El-Morsy, ... Bioorganic chemistry 96, 103656, 2020 | 30 | 2020 |
Design, synthesis, biological assessment and molecular docking studies of some new 2-Thioxo-2, 3-dihydropyrimidin-4 (1H)-ones as potential anticancer and antibacterial agents AAS El-Etrawy, FF Sherbiny Journal of Molecular Structure 1225, 129014, 2021 | 26 | 2021 |
Design, Synthesis, biological Evaluation, and molecular docking studies of novel Pyrazolo [3, 4-d] Pyrimidine derivative scaffolds as potent EGFR inhibitors and cell apoptosis … FF Sherbiny, AH Bayoumi, AM El-Morsy, M Sobhy, M Hagras Bioorganic Chemistry 116, 105325, 2021 | 17 | 2021 |
Design, synthesis and antimicrobial evaluation of some novel quinoline derivatives KMA El-Gamal, FF Sherbiny, AM El-Morsi, HE Abu-El-khair, IH Eissa, ... Pharm Pharmacol Int J 2 (5), 165-177, 2015 | 12 | 2015 |
New potential anti-SARS-CoV-2 and anti-cancer therapies of chitosan derivatives and its nanoparticles: Preparation and characterization M Ali, MI Mohamed, AT Taher, SH Mahmoud, A Mostafa, FF Sherbiny, ... Arabian Journal of Chemistry 16 (5), 104676, 2023 | 11 | 2023 |
Development of fluorinated nicotinonitriles and fused candidates as antimicrobial, antibiofilm, and enzyme inhibitors MH Ibrahim, NG El Menofy, SM El Kiki, FF Sherbiny, MMF Ismail Archiv der Pharmazie 355 (7), 2200040, 2022 | 7 | 2022 |
Evidence on the inhibitory effect of Brassica plants against Acinetobacter baumannii lipases: phytochemical analysis, in vitro, and molecular docking studies MM Sabry, AM El-Halawany, WG Fahmy, BM Eltanany, L Pont, ... BMC Complementary Medicine and Therapies 24 (1), 164, 2024 | 5 | 2024 |