| Atomic structures of low-complexity protein segments reveal kinked β sheets that assemble networks MP Hughes, MR Sawaya, DR Boyer, L Goldschmidt, JA Rodriguez, ... Science 359 (6376), 698-701, 2018 | 451 | 2018 |
| The expanding amyloid family: Structure, stability, function, and pathogenesis MR Sawaya, MP Hughes, JA Rodriguez, R Riek, DS Eisenberg Cell 184 (19), 4857-4873, 2021 | 265 | 2021 |
| Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation EL Guenther, Q Cao, H Trinh, J Lu, MR Sawaya, D Cascio, DR Boyer, ... Nature structural & molecular biology 25 (6), 463-471, 2018 | 233 | 2018 |
| TDP-43 and RNA form amyloid-like myo-granules in regenerating muscle TO Vogler, JR Wheeler, ED Nguyen, MP Hughes, KA Britson, E Lester, ... Nature 563 (7732), 508-513, 2018 | 204 | 2018 |
| The α-synuclein hereditary mutation E46K unlocks a more stable, pathogenic fibril structure DR Boyer, B Li, C Sun, W Fan, K Zhou, MP Hughes, MR Sawaya, L Jiang, ... Proceedings of the National Academy of Sciences 117 (7), 3592-3602, 2020 | 164 | 2020 |
| Structure-based discovery of fiber-binding compounds that reduce the cytotoxicity of amyloid beta L Jiang, C Liu, D Leibly, M Landau, M Zhao, MP Hughes, DS Eisenberg Elife 2, e00857, 2013 | 158 | 2013 |
| Graft weight/recipient weight ratio: how well does it predict outcome after partial liver transplants? MJ Hill, M Hughes, T Jie, M Cohen, J Lake, WD Payne, A Humar Liver Transplantation 15 (9), 1056-1062, 2009 | 117 | 2009 |
| CryoEM structure of the low-complexity domain of hnRNPA2 and its conversion to pathogenic amyloid J Lu, Q Cao, MP Hughes, MR Sawaya, DR Boyer, D Cascio, ... Nature communications 11 (1), 4090, 2020 | 94 | 2020 |
| Sexuality and cancer: How oncology nurses can address it BETTER J Mick, M Hughes, M Cohen Oncol Nurs Forum 30 (2), 152-153, 2003 | 48 | 2003 |
| Prevalence and species distribution of the low-complexity, amyloid-like, reversible, kinked segment structural motif in amyloid-like fibrils MP Hughes, L Goldschmidt, DS Eisenberg Journal of Biological Chemistry 297 (4), 2021 | 36 | 2021 |
| Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies KA Murray, MP Hughes, CJ Hu, MR Sawaya, L Salwinski, H Pan, ... Nature structural & molecular biology 29 (6), 529-536, 2022 | 28 | 2022 |
| Multimodal surveillance of SARS-CoV-2 at a university enables development of a robust outbreak response framework BA Petros, JS Paull, CH Tomkins-Tinch, BC Loftness, KC DeRuff, P Nair, ... Med 3 (12), 883-900. e13, 2022 | 27 | 2022 |
| The dynomak: An advanced spheromak reactor concept with imposed-dynamo current drive and next-generation nuclear power technologies DA Sutherland, TR Jarboe, KD Morgan, M Pfaff, ES Lavine, Y Kamikawa, ... Fusion Engineering and Design 89 (4), 412-425, 2014 | 27 | 2014 |
| Atomic structures of corkscrew‐forming segments of SOD1 reveal varied oligomer conformations S Sangwan, MR Sawaya, KA Murray, MP Hughes, DS Eisenberg Protein Science 27 (7), 1231-1242, 2018 | 26 | 2018 |
| Extended β-strands contribute to reversible amyloid formation KA Murray, D Evans, MP Hughes, MR Sawaya, CJ Hu, KN Houk, ... ACS nano 16 (2), 2154-2163, 2022 | 20 | 2022 |
| Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity Z Yang, BA Johnson, VA Meliopoulos, X Ju, P Zhang, MP Hughes, J Wu, ... Cell reports 43 (3), 2024 | 17 | 2024 |
| DNA facilitates oligomerization and prevents aggregation via DNA networks TJ Litberg, B Docter, MP Hughes, J Bourne, S Horowitz Biophysical Journal 118 (1), 162-171, 2020 | 15 | 2020 |
| A spatiotemporal reconstruction of the C. elegans pharyngeal cuticle reveals a structure rich in phase-separating proteins M Kamal, L Tokmakjian, J Knox, P Mastrangelo, J Ji, H Cai, ... Elife 11, e79396, 2022 | 12 | 2022 |
| Hydroxychloroquine for treatment of non‐hospitalized adults with COVID‐19: A meta‐analysis of individual participant data of randomized trials O Mitjà, G Reis, DR Boulware, AM Spivak, A Sarwar, C Johnston, B Webb, ... Clinical and translational science 16 (3), 524-535, 2023 | 11 | 2023 |
| Bioinformatic identification of previously unrecognized amyloidogenic proteins GM Rosenberg, KA Murray, L Salwinski, MP Hughes, R Abskharon, ... Journal of Biological Chemistry 298 (5), 2022 | 10 | 2022 |
David S. EisenbergPaul Boyer Professor, HHMI-UCLAVerified email at mbi.ucla.edu