Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN V Stambolic, A Suzuki, JL De La Pompa, GM Brothers, C Mirtsos, T Sasaki, ... Cell 95 (1), 29-39, 1998 | 3333 | 1998 |
DNA damage-induced activation of p53 by the checkpoint kinase Chk2 A Hirao, YY Kong, S Matsuoka, A Wakeham, J Ruland, H Yoshida, D Liu, ... Science 287 (5459), 1824-1827, 2000 | 1742 | 2000 |
The SYK tyrosine kinase: a crucial player in diverse biological functions A Mócsai, J Ruland, VLJ Tybulewicz Nature Reviews Immunology 10 (6), 387-402, 2010 | 1501 | 2010 |
Syk-and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17 S LeibundGut-Landmann, O Groß, MJ Robinson, F Osorio, EC Slack, ... Nature immunology 8 (6), 630-638, 2007 | 1441 | 2007 |
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence O Gross, H Poeck, M Bscheider, C Dostert, N Hannesschläger, S Endres, ... Nature 459 (7245), 433-436, 2009 | 1108 | 2009 |
Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity O Gross, A Gewies, K Finger, M Schäfer, T Sparwasser, C Peschel, ... Nature 442 (7103), 651-656, 2006 | 1025 | 2006 |
Guidelines for the use of flow cytometry and cell sorting in immunological studies* A Cossarizza, HD Chang, A Radbruch, M Akdis, I Andrä, F Annunziato, ... European journal of immunology 47 (10), 1584-1797, 2017 | 1020* | 2017 |
Guidelines for the use of flow cytometry and cell sorting in immunological studies A Cossarizza, HD Chang, A Radbruch, A Acs, D Adam, S Adam‐Klages, ... European journal of immunology 49 (10), 1457-1973, 2019 | 992 | 2019 |
A Homozygous CARD9 Mutation in a Family with Susceptibility to Fungal Infections EO Glocker, A Hennigs, M Nabavi, AA Schäffer, C Woellner, U Salzer, ... New England Journal of Medicine 361 (18), 1727-1735, 2009 | 903 | 2009 |
The target landscape of clinical kinase drugs S Klaeger, S Heinzlmeir, M Wilhelm, H Polzer, B Vick, PA Koenig, ... Science 358 (6367), eaan4368, 2017 | 833 | 2017 |
Bcl10 is a positive regulator of antigen receptor–induced activation of NF-κ B and neural tube closure J Ruland, GS Duncan, A Elia, I del Barco Barrantes, L Nguyen, S Plyte, ... Cell 104 (1), 33-42, 2001 | 695 | 2001 |
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1β production H Poeck, M Bscheider, O Gross, K Finger, S Roth, M Rebsamen, ... Nature immunology 11 (1), 63-69, 2010 | 671 | 2010 |
Aberrant NF-κB signaling in lymphoma: mechanisms, consequences, and therapeutic implications PJ Jost, J Ruland Blood 109 (7), 2700-2707, 2007 | 595 | 2007 |
Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection MJ Robinson, F Osorio, M Rosas, RP Freitas, E Schweighoffer, O Groß, ... Journal of Experimental Medicine 206 (9), 2037-2051, 2009 | 577 | 2009 |
Cutting edge: Mincle is essential for recognition and adjuvanticity of the mycobacterial cord factor and its synthetic analog trehalose-dibehenate H Schoenen, B Bodendorfer, K Hitchens, S Manzanero, K Werninghaus, ... The Journal of Immunology 184 (6), 2756-2760, 2010 | 557 | 2010 |
5′-Triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma H Poeck, R Besch, C Maihoefer, M Renn, D Tormo, SS Morskaya, ... Nature medicine 14 (11), 1256-1263, 2008 | 500 | 2008 |
K+ efflux-independent NLRP3 inflammasome activation by small molecules targeting mitochondria CJ Groß, R Mishra, KS Schneider, G Médard, J Wettmarshausen, ... Immunity 45 (4), 761-773, 2016 | 486 | 2016 |
Differential requirement for Malt1 in T and B cell antigen receptor signaling J Ruland, GS Duncan, A Wakeham, TW Mak Immunity 19 (5), 749-758, 2003 | 470 | 2003 |
Return to homeostasis: downregulation of NF-κB responses J Ruland Nature immunology 12 (8), 709-714, 2011 | 426 | 2011 |
The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity RB Damgaard, U Nachbur, M Yabal, WWL Wong, BK Fiil, M Kastirr, ... Molecular cell 46 (6), 746-758, 2012 | 423 | 2012 |