| Crystal structure of the β2 adrenergic receptor–Gs protein complex SGF Rasmussen, BT DeVree, Y Zou, AC Kruse, KY Chung, TS Kobilka, ... Nature 477 (7366), 549-555, 2011 | 3572 | 2011 |
| Structure and function of an irreversible agonist-β2 adrenoceptor complex DM Rosenbaum, C Zhang, JA Lyons, R Holl, D Aragao, DH Arlow, ... Nature 469 (7329), 236-240, 2011 | 914 | 2011 |
| ATP13A2 deficiency disrupts lysosomal polyamine export S van Veen, S Martin, C Van den Haute, V Benoy, J Lyons, R Vanhoutte, ... Nature 578 (7795), 419-424, 2020 | 264 | 2020 |
| A mechanism for intracellular release of Na+ by neurotransmitter/sodium symporters L Malinauskaite, M Quick, L Reinhard, JA Lyons, H Yano, JA Javitch, ... Nature structural & molecular biology 21 (11), 1006-1012, 2014 | 189 | 2014 |
| Structure and autoregulation of a P4-ATPase lipid flippase M Timcenko, JA Lyons, D Januliene, JJ Ulstrup, T Dieudonné, C Montigny, ... Nature 571 (7765), 366-370, 2019 | 152 | 2019 |
| Structural insights into electron transfer in caa3-type cytochrome oxidase JA Lyons, D Aragão, O Slattery, AV Pisliakov, T Soulimane, M Caffrey Nature 487 (7408), 514-518, 2012 | 131 | 2012 |
| Structural basis for polyspecificity in the POT family of proton‐coupled oligopeptide transporters JA Lyons, JL Parker, N Solcan, A Brinth, D Li, STA Shah, M Caffrey, ... EMBO reports 15 (8), 886-893, 2014 | 116 | 2014 |
| Crystal structure of the integral membrane diacylglycerol kinase D Li, JA Lyons, VE Pye, L Vogeley, D Aragão, CP Kenyon, STA Shah, ... Nature 497 (7450), 521-524, 2013 | 116 | 2013 |
| On the molecular mechanism of flippase-and scramblase-mediated phospholipid transport C Montigny, J Lyons, P Champeil, P Nissen, G Lenoir Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2016 | 105 | 2016 |
| Gating topology of the proton-coupled oligopeptide symporters PW Fowler, M Orwick-Rydmark, S Radestock, N Solcan, PM Dijkman, ... Structure 23 (2), 290-301, 2015 | 102 | 2015 |
| Structural study of a small molecule receptor bound to dimethyllysine in lysozyme RE McGovern, BD Snarr, JA Lyons, J McFarlane, AL Whiting, I Paci, F Hof, ... Chemical science 6 (1), 442-449, 2015 | 74 | 2015 |
| Expression strategies for structural studies of eukaryotic membrane proteins JA Lyons, A Shahsavar, PA Paulsen, BP Pedersen, P Nissen Current Opinion in Structural Biology 38, 137-144, 2016 | 62 | 2016 |
| Saposin-lipoprotein scaffolds for structure determination of membrane transporters JA Lyons, A Bøggild, P Nissen, J Frauenfeld Methods in enzymology 594, 85-99, 2017 | 49 | 2017 |
| A fast, simple and robust protocol for growing crystals in the lipidic cubic phase M Aherne, JA Lyons, M Caffrey Journal of Applied Crystallography 45 (6), 1330-1333, 2012 | 44 | 2012 |
| Ternary structure reveals mechanism of a membrane diacylglycerol kinase D Li, PJ Stansfeld, MSP Sansom, A Keogh, L Vogeley, N Howe, JA Lyons, ... Nature communications 6 (1), 10140, 2015 | 43 | 2015 |
| Structural basis of substrate-independent phosphorylation in a P4-ATPase lipid flippase M Timcenko, T Dieudonné, C Montigny, T Boesen, JA Lyons, G Lenoir, ... Journal of Molecular Biology 433 (16), 167062, 2021 | 37 | 2021 |
| High phosphatidylinositol 4-phosphate (PI4P)-dependent ATPase activity for the Drs2p-Cdc50p flippase after removal of its N-and C-terminal extensions H Azouaoui, C Montigny, T Dieudonné, P Champeil, A Jacquot, ... Journal of Biological Chemistry 292 (19), 7954-7970, 2017 | 36 | 2017 |
| P4-ATPases: how an old dog learnt new tricks—structure and mechanism of lipid flippases JA Lyons, M Timcenko, T Dieudonné, G Lenoir, P Nissen Current opinion in structural biology 63, 65-73, 2020 | 33 | 2020 |
| Monoacylglycerols: the workhorse lipids for crystallizing membrane proteins in mesophases M Caffrey, J Lyons, T Smyth, DJ Hart Current Topics in Membranes 63, 83-108, 2009 | 33 | 2009 |
| Autoinhibition and regulation by phosphoinositides of ATP8B1, a human lipid flippase associated with intrahepatic cholestatic disorders T Dieudonné, SA Herrera, MJ Laursen, M Lejeune, C Stock, K Slimani, ... Elife 11, e75272, 2022 | 32 | 2022 |
