| Insulin action in brain regulates systemic metabolism and brain function A Kleinridders, HA Ferris, W Cai, CR Kahn Diabetes 63 (7), 2232-2243, 2014 | 762 | 2014 |
| Astrocytic Insulin Signaling Couples Brain Glucose Uptake with Nutrient Availability C García-Cáceres, C Quarta, L Varela, Y Gao, T Gruber, B Legutko, ... Cell 166 (4), 867-880, 2016 | 524 | 2016 |
| Insulin resistance in brain alters dopamine turnover and causes behavioral disorders A Kleinridders, W Cai, L Cappellucci, A Ghazarian, WR Collins, ... Proceedings of the National Academy of Sciences 112 (11), 3463-3468, 2015 | 465 | 2015 |
| Insulin regulates astrocyte gliotransmission and modulates behavior W Cai, C Xue, M Sakaguchi, M Konishi, A Shirazian, HA Ferris, ME Li, ... The Journal of clinical investigation 128 (7), 2914-2926, 2018 | 215 | 2018 |
| Insulin signaling in the hippocampus and amygdala regulates metabolism and neurobehavior M Soto, W Cai, M Konishi, CR Kahn Proceedings of the National Academy of Sciences 116 (13), 6379-6384, 2019 | 208 | 2019 |
| Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation GX Wang, JG Meyer, W Cai, S Softic, ME Li, E Verdin, C Newgard, ... Molecular cell 74 (4), 844-857. e7, 2019 | 171 | 2019 |
| Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression W Cai, M Sakaguchi, A Kleinridders, G Gonzalez-Del Pino, JM Dreyfuss, ... Nature communications 8 (1), 14892, 2017 | 171 | 2017 |
| Insulin and IGF-1 receptors regulate FoxO-mediated signaling in muscle proteostasis BT O’Neill, KY Lee, K Klaus, S Softic, MT Krumpoch, J Fentz, KI Stanford, ... The Journal of Clinical Investigation 126 (9), 3433-3446, 2016 | 169 | 2016 |
| Adipocyte Dynamics and Reversible Metabolic Syndrome in Mice with an Inducible Adipocyte-Specific Deletion of the Insulin Receptor M Sakaguchi, S Fujisaka, W Cai, JN Winnay, M Konishi, BT O'Neill, M Li, ... Cell metabolism 25 (2), 448-462, 2017 | 136 | 2017 |
| Endothelial insulin receptors differentially control insulin signaling kinetics in peripheral tissues and brain of mice M Konishi, M Sakaguchi, SM Lockhart, W Cai, ME Li, EP Homan, ... Proceedings of the National Academy of Sciences 114 (40), E8478-E8487, 2017 | 131 | 2017 |
| FoxK1 and FoxK2 in insulin regulation of cellular and mitochondrial metabolism M Sakaguchi, W Cai, CH Wang, CT Cederquist, M Damasio, EP Homan, ... Nature Communications 10 (1), 1582, 2019 | 94 | 2019 |
| COVID-19 induces new-onset insulin resistance and lipid metabolic dysregulation via regulation of secreted metabolic factors X He, C Liu, J Peng, Z Li, F Li, J Wang, A Hu, M Peng, K Huang, D Fan, ... Signal transduction and targeted therapy 6 (1), 427, 2021 | 93 | 2021 |
| Viral insulin-like peptides activate human insulin and IGF-1 receptor signaling: A paradigm shift for host–microbe interactions E Altindis, W Cai, M Sakaguchi, F Zhang, W GuoXiao, F Liu, P De Meyts, ... Proceedings of the National Academy of Sciences 115 (10), 2461-2466, 2018 | 86 | 2018 |
| IGF-1 mediated Neurogenesis Involves a Novel RIT1/Akt/Sox2 Cascade S Mir, W Cai, SW Carlson, KE Saatman, DA Andres Scientific reports 7 (1), 3283, 2017 | 86 | 2017 |
| Insulin action in the brain: cell types, circuits, and diseases W Chen, W Cai, B Hoover, CR Kahn Trends in neurosciences 45 (5), 384-400, 2022 | 79 | 2022 |
| An evolutionarily conserved Rit GTPase–p38 MAPK signaling pathway mediates oxidative stress resistance W Cai, JL Rudolph, SMW Harrison, L Jin, AL Frantz, DA Harrison, ... Molecular biology of the cell 22 (17), 3231-3241, 2011 | 78 | 2011 |
| Multi-dimensional Transcriptional Remodeling by Physiological Insulin In Vivo TM Batista, R Garcia-Martin, W Cai, M Konishi, BT O’Neill, M Sakaguchi, ... Cell reports 26 (12), 3429-3443. e3, 2019 | 75 | 2019 |
| Insulin action in the brain regulates mitochondrial stress responses and reduces diet-induced weight gain K Wardelmann, S Blümel, M Rath, E Alfine, C Chudoba, M Schell, W Cai, ... Molecular metabolism 21, 68-81, 2019 | 67 | 2019 |
| Distinct signaling by insulin and IGF-1 receptors and their extra-and intracellular domains H Nagao, W Cai, NJ Wewer Albrechtsen, M Steger, TM Batista, H Pan, ... Proceedings of the National Academy of Sciences 118 (17), e2019474118, 2021 | 66 | 2021 |
| Rit subfamily small GTPases: regulators in neuronal differentiation and survival GX Shi, W Cai, DA Andres Cellular signalling 25 (10), 2060-2068, 2013 | 60 | 2013 |