Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation VA Gerriets, RJ Kishton, AG Nichols, AN Macintyre, M Inoue, O Ilkayeva, ... The Journal of clinical investigation 125 (1), 194-207, 2015 | 728 | 2015 |
Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer S Raghavan, PS Winter, AW Navia, HL Williams, A DenAdel, KE Lowder, ... Cell 184 (25), 6119-6137. e26, 2021 | 360 | 2021 |
Systematic identification of signaling pathways with potential to confer anticancer drug resistance CA Martz, KA Ottina, KR Singleton, JS Jasper, SE Wardell, ... Science signaling 7 (357), ra121-ra121, 2014 | 233 | 2014 |
Targeting MCL-1/BCL-XL Forestalls the Acquisition of Resistance to ABT-199 in Acute Myeloid Leukemia KH Lin, PS Winter, A Xie, C Roth, CA Martz, EM Stein, GR Anderson, ... Scientific reports 6 (1), 27696, 2016 | 209 | 2016 |
Systematic mapping of BCL-2 gene dependencies in cancer reveals molecular determinants of BH3 mimetic sensitivity RS Soderquist, L Crawford, E Liu, M Lu, A Agarwal, GR Anderson, KH Lin, ... Nature communications 9 (1), 3513, 2018 | 123 | 2018 |
A landscape of therapeutic cooperativity in KRAS mutant cancers reveals principles for controlling tumor evolution GR Anderson, PS Winter, KH Lin, DP Nussbaum, M Cakir, EM Stein, ... Cell reports 20 (4), 999-1015, 2017 | 101 | 2017 |
RAS signaling promotes resistance to JAK inhibitors by suppressing BAD-mediated apoptosis PS Winter, KA Sarosiek, KH Lin, M Meggendorfer, S Schnittger, A Letai, ... Science signaling 7 (357), ra122-ra122, 2014 | 94 | 2014 |
Epstein-Barr virus ensures B cell survival by uniquely modulating apoptosis at early and late times after infection AM Price, J Dai, Q Bazot, L Patel, PA Nikitin, R Djavadian, PS Winter, ... Elife 6, e22509, 2017 | 81 | 2017 |
Deciphering the immunopeptidome in vivo reveals new tumour antigens AM Jaeger, LE Stopfer, R Ahn, EA Sanders, DA Sandel, WA Freed-Pastor, ... Nature 607 (7917), 149-155, 2022 | 67 | 2022 |
Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer KH Lin, JC Rutter, A Xie, B Pardieu, ET Winn, RD Bello, A Forget, ... Nature genetics 52 (4), 408-417, 2020 | 65 | 2020 |
PIK3CA mutations enable targeting of a breast tumor dependency through mTOR-mediated MCL-1 translation GR Anderson, SE Wardell, M Cakir, L Crawford, JC Leeds, DP Nussbaum, ... Science translational medicine 8 (369), 369ra175-369ra175, 2016 | 64 | 2016 |
Mapping nucleosome positions using DNase-seq J Zhong, K Luo, PS Winter, GE Crawford, ES Iversen, AJ Hartemink Genome research 26 (3), 351-364, 2016 | 64 | 2016 |
Optofluidic real-time cell sorter for longitudinal CTC studies in mouse models of cancer B Hamza, SR Ng, SM Prakadan, FF Delgado, CR Chin, EM King, LF Yang, ... Proceedings of the National Academy of Sciences 116 (6), 2232-2236, 2019 | 62 | 2019 |
Spatially resolved single-cell assessment of pancreatic cancer expression subtypes reveals co-expressor phenotypes and extensive intratumoral heterogeneity HL Williams, A Dias Costa, J Zhang, S Raghavan, PS Winter, KS Kapner, ... Cancer research 83 (3), 441-455, 2023 | 54 | 2023 |
CDK4/6 therapeutic intervention and viable alternative to taxanes in CRPC JP Stice, SE Wardell, JD Norris, AP Yllanes, HM Alley, VO Haney, ... Molecular Cancer Research 15 (6), 660-669, 2017 | 47 | 2017 |
Systemic acquired resistance in moss: further evidence for conserved defense mechanisms in plants PS Winter, CE Bowman, PJ Villani, TE Dolan, NR Hauck PloS One 9 (7), e101880, 2014 | 30 | 2014 |
Mechanisms of resistance to oncogenic KRAS inhibition in pancreatic cancer J Dilly, MT Hoffman, L Abbassi, Z Li, F Paradiso, BD Parent, ... Cancer discovery 14 (11), 2135-2161, 2024 | 26 | 2024 |
Cancer tissue of origin constrains the growth and metabolism of metastases S Sivanand, Y Gultekin, PS Winter, SY Vermeulen, KM Tchourine, ... Nature Metabolism 6 (9), 1668-1681, 2024 | 9 | 2024 |
The tumor microenvironment drives transcriptional phenotypes and their plasticity in metastatic pancreatic cancer S Raghavan, PS Winter, AW Navia, HL Williams, A DenAdel, RL Kalekar, ... Biorxiv, 2020.08. 25.256214, 2020 | 7 | 2020 |
ABL kinases regulate the stabilization of HIF-1α and MYC through CPSF1 B Mayro, JP Hoj, CG Cerda-Smith, HM Hutchinson, MW Caminear, ... Proceedings of the National Academy of Sciences 120 (16), e2210418120, 2023 | 4 | 2023 |