| Rationally designed small molecules that target both the DNA and RNA causing myotonic dystrophy type 1 L Nguyen, LM Luu, S Peng, JF Serrano, HYE Chan, SC Zimmerman Journal of the American Chemical Society 137 (44), 14180-14189, 2015 | 125 | 2015 |
| Targeting toxic RNAs that cause myotonic dystrophy type 1 (DM1) with a bisamidinium inhibitor CH Wong, L Nguyen, J Peh, LM Luu, JS Sanchez, SL Richardson, ... Journal of the American Chemical Society 136 (17), 6355-6361, 2014 | 115 | 2014 |
| Developing bivalent ligands to target CUG triplet repeats, the causative agent of myotonic dystrophy type 1 AH Jahromi, Y Fu, KA Miller, L Nguyen, LM Luu, AM Baranger, ... Journal of medicinal chemistry 56 (23), 9471-9481, 2013 | 63 | 2013 |
| A Potent Inhibitor of Protein Sequestration by Expanded Triplet (CUG) Repeats that Shows Phenotypic Improvements in a Drosophila Model of Myotonic Dystrophy LM Luu, L Nguyen, S Peng, JY Lee, HY Lee, CH Wong, PJ Hergenrother, ... ChemMedChem 11 (13), 1428-1435, 2016 | 49 | 2016 |
| Intrinsically cell-penetrating multivalent and multitargeting ligands for myotonic dystrophy type 1 JY Lee, Y Bai, UV Chembazhi, S Peng, K Yum, LM Luu, LD Hagler, ... Proceedings of the National Academy of Sciences 116 (18), 8709-8714, 2019 | 48 | 2019 |
| Expanded DNA and RNA trinucleotide repeats in myotonic dystrophy type 1 select their own multitarget, sequence-selective inhibitors LD Hagler, LM Luu, M Tonelli, JY Lee, SM Hayes, SE Bonson, JI Vergara, ... Biochemistry 59 (37), 3463-3472, 2020 | 11 | 2020 |
| Leveraging intracellular ALDH1A1 activity for selective cancer stem-like cell labeling and targeted treatment via in vivo click reaction Y Bo, J Zhou, K Cai, Y Wang, Y Feng, W Li, Y Jiang, SH Kuo, J Roy, ... Proceedings of the National Academy of Sciences 120 (36), e2302342120, 2023 | 9 | 2023 |
| Versatile target-guided screen for discovering bidirectional transcription inhibitors of a trinucleotide repeat disease LD Hagler, SB Krueger, LM Luu, AN Lanzendorf, NL Mitchell, JI Vergara, ... ACS Medicinal Chemistry Letters 12 (6), 935-940, 2021 | 8 | 2021 |
| E.; Baranger, AM; Hergenrother, PJ; Zimmerman, SC Targeting Toxic RNAs that Cause Myotonic Dystrophy Type 1 (DM1) with a Bisamidinium Inhibitor CH Wong, L Nguyen, J Peh, LM Luu, JS Sanchez, SL Richardson, ... J. Am. Chem. Soc 136 (17), 6355-6361, 2014 | 8 | 2014 |
| Bisamidinium-based inhibitors for the treatment of myotonic dystrophy SC Zimmerman, LM Luu, LTT Nguyen US Patent 10,266,520, 2019 | 2 | 2019 |
| Compounds and methods for myotonic dystrophy therapy SC Zimmerman, LM Luu, LTT Nguyen US Patent 9,376,421, 2016 | 1 | 2016 |
| Template-assisted click chemistry as a therapuetic strategy for myotonic dystrophy type 1 (DM1) L Hagler, L Luu, S Zimmerman ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019 | | 2019 |
| Approaches to the assembly of potent therapeutic agents for the treatment of myotonic dystrophy LM Luu University of Illinois at Urbana-Champaign, 2016 | | 2016 |
| DNA and RNA in multi-target drug design for the microsatellite disease myotonic dystrophy S Zimmerman, L Luu, L Nguyen, J Serrano, J Lee ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 251, 2016 | | 2016 |
| On-target synthesis and selection of modular therapeutic agents for myotonic dystrophy L Luu ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 251, 2016 | | 2016 |
| Discovery of bis-amidinium ligands as potential lead agents for myotonic dystrophy type 1 LM Luu, L Nguyen, SC Zimmerman ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 248, 2014 | | 2014 |
| Developing bivalent ligands to target CUG triplet repeats, the causative agent of myotonic dystrophy type 1 KA Miller, AH Jahromi, L Nguyen, L Luu, SC Zimmerman ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 247, 2014 | | 2014 |
| Leveraging intracellular ALDH1A1 activity for selective cancer stem-like cell labeling and targeted treatment via in vivo click reaction | | |
| The Bivalent Ligand Approach Leads to a Bioactive Inhibitor of MBNL1· CUG exp Complex AH Jahromi, Y Fu, KA Miller, L Nguyen, LM Luu, AM Baranger, ... | | |