| A compact, high-accuracy Cas9 with a dinucleotide PAM for in vivo genome editing A Edraki, A Mir, R Ibraheim, I Gainetdinov, Y Yoon, CQ Song, Y Cao, ... Molecular cell 73 (4), 714-726. e4, 2019 | 259 | 2019 |
| NmeCas9 is an intrinsically high-fidelity genome-editing platform N Amrani, XD Gao, P Liu, A Edraki, A Mir, R Ibraheim, A Gupta, KE Sasaki, ... Genome Biology 19, 1-25, 2018 | 142 | 2018 |
| All-in-one adeno-associated virus delivery and genome editing by Neisseria meningitidis Cas9 in vivo R Ibraheim, CQ Song, N Mir, Aamir, Amrani, EJ Xue, Sontheimer, Wen Genome Biology 19 (137), 2018 | 114 | 2018 |
| Structures of Neisseria meningitidis Cas9 complexes in catalytically poised and anti-CRISPR-inhibited states W Sun, J Yang, Z Cheng, N Amrani, C Liu, K Wang, R Ibraheim, A Edraki, ... Molecular cell 76 (6), 938-952. e5, 2019 | 100 | 2019 |
| Tissue-restricted genome editing in vivo specified by microRNA-repressible anti-CRISPR proteins J Lee, H Mou, R Ibraheim, SQ Liang, P Liu, W Xue, EJ Sontheimer Rna 25 (11), 1421-1431, 2019 | 99 | 2019 |
| Potent Cas9 inhibition in bacterial and human cells by AcrIIC4 and AcrIIC5 anti-CRISPR proteins J Lee, A Mir, A Edraki, B Garcia, N Amrani, HE Lou, I Gainetdinov, ... MBio 9 (6), 10.1128/mbio. 02321-18, 2018 | 98 | 2018 |
| Self-inactivating, all-in-one AAV vectors for precision Cas9 genome editing via homology-directed repair in vivo R Ibraheim, PWL Tai, A Mir, N Javeed, J Wang, TC Rodríguez, ... Nature communications 12 (1), 6267, 2021 | 85 | 2021 |
| CRISPR-enhanced human adipocyte browning as cell therapy for metabolic disease E Tsagkaraki, SM Nicoloro, T DeSouza, J Solivan-Rivera, A Desai, ... Nature Communications 12 (1), 6931, 2021 | 59 | 2021 |
| A scalable and accurate method for quantifying vector genomes of recombinant adeno-associated viruses in crude lysate J Ai, R Ibraheim, PWL Tai, G Gao Human gene therapy methods 28 (3), 139-147, 2017 | 55 | 2017 |
| Syntheses, characterization, density functional theory calculations, and activity of tridentate SNS zinc pincer complexes based on bis-imidazole or bis-triazole precursors JR Miecznikowski, W Lo, MA Lynn, S Jain, LC Keilich, NF Kloczko, ... Inorganica Chimica Acta 387, 25-36, 2012 | 41 | 2012 |
| Efficient homology-directed repair with circular single-stranded DNA donors S Iyer, A Mir, J Vega-Badillo, BP Roscoe, R Ibraheim, LJ Zhu, J Lee, P Liu, ... The CRISPR journal 5 (5), 685-701, 2022 | 30 | 2022 |
| Efficient homology-directed repair with circular ssDNA donors S Iyer, A Mir, J Vega-Badillo, BP Roscoe, R Ibraheim, LJ Zhu, J Lee, P Liu, ... bioRxiv, 864199, 2019 | 11 | 2019 |
| Sleeping Beauty mRNA-LNP enables stable rAAV transgene expression in mouse and NHP hepatocytes and improves vector potency PM Zakas, SC Cunningham, A Doherty, EB van Dijk, R Ibraheim, S Yu, ... Molecular Therapy 32 (10), 3356-3371, 2024 | 6 | 2024 |
| Targeted CRISPR Delivery Platforms EJ Sontheimer, R Ibraheim, W Xue, A Mir, A Edraki, I Gainetdinov US Patent App. 16/186,352, 2022 | 1 | 2022 |
| Correction of the Human Wilson’s Disease Mutation in an Engineered Disease Mouse Model Using RNA Gene Writers R Ibraheim, M Bedekar, L Apponi, E English, S Sun, M Caldwell, CZ Cai, ... 27th Annual Meeting of the American Society of Gene & Cell Therapy 32 (4), 306, 2024 | | 2024 |
| Direct ITR-To-ITR Nanopore Sequencing of Plasmid and Vector Preparations and Their Implications for In Vivo Gene-Editing Vector Performance S Namkung, R Ibraheim, NT Tran, E Sontheimer, G Gao, P Tai MOLECULAR THERAPY 30 (4), 22-23, 2022 | | 2022 |
| Genome Engineering Goes Viral: Repurposing of Adeno-associated Viral Vectors for CRISPR-mediated in Vivo Genome Engineering RR Ibraheim | | 2020 |
| eScholarship@ UMassChan R Ibraheim, CQ Song, A Mir, N Amrani | | 2018 |
Erik SontheimerRNA Therapeutics Institute, UMass Medical SchoolVerified email at umassmed.edu