Transformation from non-small-cell lung cancer to small-cell lung cancer: molecular drivers and cells of origin MG Oser, MJ Niederst, LV Sequist, JA Engelman The Lancet Oncology 16 (4), e165-e172, 2015 | 920 | 2015 |
Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation M Oser, H Yamaguchi, CC Mader, JJ Bravo-Cordero, M Arias, X Chen, ... Journal of Cell Biology 186 (4), 571-587, 2009 | 445 | 2009 |
Polycomb group protein ezh2 controls actin polymerization and cell signaling I Su, MW Dobenecker, E Dickinson, M Oser, A Basavaraj, R Marqueron, ... Cell 121 (3), 425-436, 2005 | 426 | 2005 |
An EGFR–Src–Arg–cortactin pathway mediates functional maturation of invadopodia and breast cancer cell invasion CC Mader, M Oser, MAO Magalhaes, JJ Bravo-Cordero, J Condeelis, ... Cancer research 71 (5), 1730-1741, 2011 | 353 | 2011 |
A Mena invasion isoform potentiates EGF-induced carcinoma cell invasion and metastasis U Philippar, ET Roussos, M Oser, H Yamaguchi, HD Kim, S Giampieri, ... Developmental cell 15 (6), 813-828, 2008 | 339 | 2008 |
Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway MAO Magalhaes, DR Larson, CC Mader, JJ Bravo-Cordero, H Gil-Henn, ... Journal of Cell Biology 195 (5), 903-920, 2011 | 257 | 2011 |
A novel spatiotemporal RhoC activation pathway locally regulates cofilin activity at invadopodia JJ Bravo-Cordero, M Oser, X Chen, R Eddy, L Hodgson, J Condeelis Current Biology 21 (8), 635-644, 2011 | 232 | 2011 |
The cofilin activity cycle in lamellipodia and invadopodia M Oser, J Condeelis Journal of cellular biochemistry 108 (6), 1252-1262, 2009 | 228 | 2009 |
CDK7 inhibition potentiates genome instability triggering anti-tumor immunity in small cell lung cancer H Zhang, CL Christensen, R Dries, MG Oser, J Deng, B Diskin, F Li, Y Pan, ... Cancer cell 37 (1), 37-54. e9, 2020 | 192 | 2020 |
Specific tyrosine phosphorylation sites on cortactin regulate Nck1-dependent actin polymerization in invadopodia M Oser, CC Mader, H Gil-Henn, M Magalhaes, JJ Bravo-Cordero, ... Journal of cell science 123 (21), 3662-3673, 2010 | 192 | 2010 |
New approaches to SCLC therapy: from the laboratory to the clinic JT Poirier, J George, TK Owonikoko, A Berns, E Brambilla, LA Byers, ... Journal of Thoracic Oncology 15 (4), 520-540, 2020 | 170 | 2020 |
Cells Lacking the RB1 Tumor Suppressor Gene Are Hyperdependent on Aurora B Kinase for Survival MG Oser, R Fonseca, AA Chakraborty, R Brough, A Spektor, RB Jennings, ... Cancer discovery 9 (2), 230-247, 2019 | 157 | 2019 |
Deubiquitinases maintain protein homeostasis and survival of cancer cells upon glutathione depletion IS Harris, JE Endress, JL Coloff, LM Selfors, SK McBrayer, JM Rosenbluth, ... Cell metabolism 29 (5), 1166-1181. e6, 2019 | 146 | 2019 |
N‐WASP and cortactin are involved in invadopodium‐dependent chemotaxis to EGF in breast tumor cells V DesMarais, H Yamaguchi, M Oser, L Soon, G Mouneimne, C Sarmiento, ... Cell motility and the cytoskeleton 66 (6), 303-316, 2009 | 146 | 2009 |
Intrinsic immunogenicity of small cell lung carcinoma revealed by its cellular plasticity NR Mahadevan, EH Knelson, JO Wolff, A Vajdi, M Saigí, M Campisi, ... Cancer discovery 11 (8), 1952-1969, 2021 | 134 | 2021 |
The KDM5A/RBP2 histone demethylase represses NOTCH signaling to sustain neuroendocrine differentiation and promote small cell lung cancer tumorigenesis MG Oser, AH Sabet, W Gao, AA Chakraborty, AC Schinzel, RB Jennings, ... Genes & development 33 (23-24), 1718-1738, 2019 | 100 | 2019 |
Nck1 and Grb2 localization patterns can distinguish invadopodia from podosomes M Oser, A Dovas, D Cox, J Condeelis European journal of cell biology 90 (2-3), 181-188, 2011 | 72 | 2011 |
Cyclin D–CDK4 relieves cooperative repression of proliferation and cell cycle gene expression by DREAM and RB AE Schade, MG Oser, HE Nicholson, JA DeCaprio Oncogene 38 (25), 4962-4976, 2019 | 69 | 2019 |
Liquid biopsy epigenomic profiling for cancer subtyping SC Baca, JH Seo, MP Davidsohn, B Fortunato, K Semaan, S Sotudian, ... Nature medicine 29 (11), 2737-2741, 2023 | 43 | 2023 |
Targeting oncoproteins with a positive selection assay for protein degraders V Koduri, L Duplaquet, BL Lampson, AC Wang, AH Sabet, M Ishoey, ... Science Advances 7 (6), eabd6263, 2021 | 35 | 2021 |