The role of recessive inheritance in early-onset epileptic encephalopathies: a combined whole-exome sequencing and copy number study SM Papuc, L Abela, K Steindl, A Begemann, TL Simmons, B Schmitt, ... European journal of human genetics 27 (3), 408-421, 2019 | 78 | 2019 |
A survey of biological building blocks for synthetic molecular communication systems CA Söldner, E Socher, V Jamali, W Wicke, A Ahmadzadeh, HG Breitinger, ... IEEE Communications Surveys & Tutorials 22 (4), 2765-2800, 2020 | 68 | 2020 |
The chemical class of quinazoline compounds provides a core structure for the design of anticytomegaloviral kinase inhibitors C Hutterer, S Hamilton, M Steingruber, I Zeitträger, H Bahsi, N Thuma, ... Antiviral Research 134, 130-143, 2016 | 50 | 2016 |
Mutations in the B. 1.1. 7 SARS-CoV-2 spike protein reduce receptor-binding affinity and induce a flexible link to the fusion peptide E Socher, M Conrad, L Heger, F Paulsen, H Sticht, F Zunke, P Arnold Biomedicines 9 (5), 525, 2021 | 42 | 2021 |
The pH-dependent client release from the collagen-specific chaperone HSP47 is triggered by a tandem histidine pair S Oecal, E Socher, M Uthoff, C Ernst, F Zaucke, H Sticht, U Baumann, ... Journal of Biological Chemistry 291 (24), 12612-12626, 2016 | 39 | 2016 |
A pair of noncompeting neutralizing human monoclonal antibodies protecting from disease in a SARS‐CoV‐2 infection model AS Peter, E Roth, SR Schulz, K Fraedrich, T Steinmetz, D Damm, ... European journal of immunology 52 (5), 770-783, 2022 | 38 | 2022 |
Molecular dynamics simulations of the delta and omicron SARS-CoV-2 spike–ACE2 complexes reveal distinct changes between both variants E Socher, L Heger, F Paulsen, F Zunke, P Arnold Computational and structural biotechnology journal 20, 1168-1176, 2022 | 37 | 2022 |
Mimicking titration experiments with MD simulations: A protocol for the investigation of pH-dependent effects on proteins E Socher, H Sticht Scientific Reports 6 (1), 22523, 2016 | 33 | 2016 |
Cyclins B1, T1, and H differ in their molecular mode of interaction with cytomegalovirus protein kinase pUL97 M Steingruber, L Keller, E Socher, S Ferre, AM Hesse, Y Couté, F Hahn, ... Journal of Biological Chemistry 294 (15), 6188-6203, 2019 | 25 | 2019 |
The conformational stability of nonfibrillar amyloid-β peptide oligomers critically depends on the C-terminal peptide length E Socher, H Sticht, AHC Horn ACS chemical neuroscience 5 (3), 161-167, 2014 | 25 | 2014 |
Proteomic interaction patterns between human cyclins, the cyclin-dependent kinase ortholog pUL97 and additional cytomegalovirus proteins M Steingruber, A Kraut, E Socher, H Sticht, A Reichel, T Stamminger, ... Viruses 8 (8), 219, 2016 | 22 | 2016 |
Computational decomposition reveals reshaping of the SARS‐CoV‐2–ACE2 interface among viral variants expressing the N501Y mutation E Socher, M Conrad, L Heger, F Paulsen, H Sticht, F Zunke, P Arnold Journal of cellular biochemistry 122 (12), 1863-1872, 2021 | 21 | 2021 |
Role of two single nucleotide polymorphisms in secreted frizzled related protein 1 and bladder cancer risk A Rogler, S Hoja, E Socher, E Nolte, S Wach, W Wieland, F Hofstädter, ... International journal of clinical and experimental pathology 6 (10), 1984, 2013 | 21 | 2013 |
XCR1 expression distinguishes human conventional dendritic cell type 1 with full effector functions from their immediate precursors L Heger, L Hatscher, C Liang, CHK Lehmann, L Amon, JJ Lühr, ... Proceedings of the National Academy of Sciences 120 (33), e2300343120, 2023 | 19 | 2023 |
The interaction between cyclin B1 and cytomegalovirus protein kinase pUL97 is determined by an active kinase domain M Steingruber, E Socher, C Hutterer, R Webel, T Bergbrede, T Lenac, ... Viruses 7 (8), 4582-4601, 2015 | 18 | 2015 |
Transfer of HTLV-1 p8 and Gag to target T-cells depends on VASP, a novel interaction partner of p8 N Donhauser, E Socher, S Millen, S Heym, H Sticht, AK Thoma-Kress PLoS Pathogens 16 (9), e1008879, 2020 | 14 | 2020 |
Conformational dynamics of herpesviral NEC proteins in different oligomerization states B Diewald, E Socher, CA Söldner, H Sticht International journal of molecular sciences 19 (10), 2908, 2018 | 14 | 2018 |
Characterization of SARS-CoV-2 Escape Mutants to a Pair of Neutralizing Antibodies Targeting the RBD and the NTD AS Peter, E Grüner, E Socher, K Fraedrich, E Richel, ... International Journal of Molecular Sciences 23 (15), 8177, 2022 | 10 | 2022 |
Functional relevance of the interaction between human cyclins and the cytomegalovirus-encoded CDK-like protein kinase pUL97 M Schütz, M Steingruber, E Socher, R Müller, S Wagner, M Kögel, H Sticht, ... Viruses 13 (7), 1248, 2021 | 10 | 2021 |
Dynamic regulatory interaction between cytomegalovirus major tegument protein pp65 and protein kinase pUL97 in intracellular compartments, dense bodies and virions P König, N Büscher, M Steingruber, E Socher, H Sticht, S Tenzer, ... Journal of General Virology 98 (11), 2850-2863, 2017 | 10 | 2017 |