Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels H Watanabe, J Vriens, J Prenen, G Droogmans, T Voets, B Nilius Nature 424 (6947), 434-438, 2003 | 1172 | 2003 |
Heat-evoked activation of TRPV4 channels in a HEK293 cell expression system and in native mouse aorta endothelial cells H Watanabe, J Vriens, SH Suh, CD Benham, G Droogmans, B Nilius Journal of Biological Chemistry 277 (49), 47044-47051, 2002 | 827 | 2002 |
Cell swelling, heat, and chemical agonists use distinct pathways for the activation of the cation channel TRPV4 J Vriens, H Watanabe, A Janssens, G Droogmans, T Voets, B Nilius Proceedings of the National Academy of Sciences 101 (1), 396-401, 2004 | 746 | 2004 |
Activation of TRPV4 channels (hVRL-2/mTRP12) by phorbol derivatives H Watanabe, JB Davis, D Smart, JC Jerman, GD Smith, P Hayes, J Vriens, ... Journal of Biological Chemistry 277 (16), 13569-13577, 2002 | 707 | 2002 |
TRPM3 is a nociceptor channel involved in the detection of noxious heat J Vriens, G Owsianik, T Hofmann, SE Philipp, J Stab, X Chen, M Benoit, ... Neuron 70 (3), 482-494, 2011 | 650 | 2011 |
Inhibition of the glycolytic activator PFKFB3 in endothelium induces tumor vessel normalization, impairs metastasis, and improves chemotherapy AR Cantelmo, LC Conradi, A Brajic, J Goveia, J Kalucka, A Pircher, ... Cancer cell 30 (6), 968-985, 2016 | 621 | 2016 |
TRPV4 calcium entry channel: a paradigm for gating diversity B Nilius, J Vriens, J Prenen, G Droogmans, T Voets American Journal of Physiology-Cell Physiology 286 (2), C195-C205, 2004 | 572 | 2004 |
Pharmacology of vanilloid transient receptor potential cation channels J Vriens, G Appendino, B Nilius Molecular pharmacology 75 (6), 1262-1279, 2009 | 534 | 2009 |
A TRP channel trio mediates acute noxious heat sensing I Vandewauw, K De Clercq, M Mulier, K Held, S Pinto, N Van Ranst, ... Nature 555 (7698), 662-666, 2018 | 476 | 2018 |
Peripheral thermosensation in mammals J Vriens, B Nilius, T Voets Nature Reviews Neuroscience 15 (9), 573-589, 2014 | 464 | 2014 |
Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis W Everaerts, X Zhen, D Ghosh, J Vriens, T Gevaert, JP Gilbert, ... Proceedings of the National Academy of Sciences 107 (44), 19084-19089, 2010 | 452 | 2010 |
Modulation of the Ca2 Permeable Cation Channel TRPV4 by Cytochrome P450 Epoxygenases in Vascular Endothelium J Vriens, G Owsianik, B Fisslthaler, M Suzuki, A Janssens, T Voets, ... Circulation research 97 (9), 908-915, 2005 | 451 | 2005 |
Patient-derived organoids from endometrial disease capture clinical heterogeneity and are amenable to drug screening M Boretto, N Maenhoudt, X Luo, A Hennes, B Boeckx, B Bui, R Heremans, ... Nature cell biology 21 (8), 1041-1051, 2019 | 392 | 2019 |
Molecular determinants of permeation through the cation channel TRPV4 T Voets, J Prenen, J Vriens, H Watanabe, A Janssens, U Wissenbach, ... Journal of Biological Chemistry 277 (37), 33704-33710, 2002 | 388 | 2002 |
Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voiding T Gevaert, J Vriens, A Segal, W Everaerts, T Roskams, K Talavera, ... The Journal of clinical investigation 117 (11), 3453-3462, 2007 | 374 | 2007 |
The concise guide to pharmacology 2019/20: Ion channels SPH Alexander, A Mathie, JA Peters, EL Veale, J Striessnig, E Kelly, ... British journal of pharmacology 176, S142-S228, 2019 | 369 | 2019 |
TRPV4-mediated calcium influx regulates terminal differentiation of osteoclasts R Masuyama, J Vriens, T Voets, Y Karashima, G Owsianik, R Vennekens, ... Cell metabolism 8 (3), 257-265, 2008 | 341 | 2008 |
Role of Caveolar Compartmentation in Endothelium-Derived Hyperpolarizing Factor–Mediated Relaxation: Ca2+ Signals and Gap Junction Function Are … J Saliez, C Bouzin, G Rath, P Ghisdal, F Desjardins, R Rezzani, ... Circulation 117 (8), 1065-1074, 2008 | 258 | 2008 |
The concise guide to pharmacology 2021/22: Ion channels SPH Alexander, A Mathie, JA Peters, EL Veale, J Striessnig, E Kelly, ... British Journal of Pharmacology 178, S157-S245, 2021 | 257 | 2021 |
TRPM1 forms ion channels associated with melanin content in melanocytes E Oancea, J Vriens, S Brauchi, J Jun, I Splawski, DE Clapham Science signaling 2 (70), ra21-ra21, 2009 | 249 | 2009 |