Juvenile myelomonocytic leukemia displays mutations in components of the RAS pathway and the PRC2 network A Caye, M Strullu, F Guidez, B Cassinat, S Gazal, O Fenneteau, E Lainey, ... Nature genetics 47 (11), 1334-1340, 2015 | 193 | 2015 |
Functional dysregulation of CDC42 causes diverse developmental phenotypes S Martinelli, OHF Krumbach, F Pantaleoni, S Coppola, E Amin, ... The American Journal of Human Genetics 102 (2), 309-320, 2018 | 180 | 2018 |
Deciphering the molecular and functional basis of RHOGAP family proteins: a systematic approach toward selective inactivation of RHO family proteins E Amin, M Jaiswal, U Derewenda, K Reis, K Nouri, KT Koessmeier, ... Journal of Biological Chemistry 291 (39), 20353-20371, 2016 | 122 | 2016 |
Mitochondrial ClpP serine protease-biological function and emerging target for cancer therapy K Nouri, Y Feng, AD Schimmer Cell death & disease 11 (10), 841, 2020 | 93 | 2020 |
Subcellular fractionation and localization studies reveal a direct interaction of the fragile X mental retardation protein (FMRP) with nucleolin MS Taha, K Nouri, LG Milroy, JM Moll, C Herrmann, L Brunsveld, ... PloS one 9 (3), e91465, 2014 | 74 | 2014 |
Identification of Celastrol as a Novel YAP-TEAD Inhibitor for Cancer Therapy by High Throughput Screening with Ultrasensitive YAP/TAZ–TEAD Biosensors K Nouri, T Azad, M Ling, HJJ van Rensburg, A Pipchuk, H Shen, Y Hao, ... Cancers 11 (10), 1596, 2019 | 66 | 2019 |
A gain-of-functional screen identifies the Hippo pathway as a central mediator of receptor tyrosine kinases during tumorigenesis T Azad, K Nouri, HJJ van Rensburg, SM Maritan, L Wu, Y Hao, ... Oncogene 39 (2), 334-355, 2019 | 63 | 2019 |
The centrosomal adaptor TACC3 and the microtubule polymerase chTOG interact via defined C-terminal subdomains in an Aurora-A kinase-independent manner HC Thakur, M Singh, L Nagel-Steger, J Kremer, D Prumbaum, EK Fansa, ... Journal of Biological Chemistry 289 (1), 74-88, 2014 | 53 | 2014 |
A kinome-wide screen using a NanoLuc LATS luminescent biosensor identifies ALK as a novel regulator of the Hippo pathway in tumorigenesis and immune evasion K Nouri, T Azad, E Lightbody, P Khanal, CJ Nicol, X Yang The FASEB Journal 33 (11), 12487, 2019 | 44 | 2019 |
IQGAP1 interaction with RHO family proteins revisited: kinetic and equilibrium evidence for multiple distinct binding sites K Nouri, EK Fansa, E Amin, R Dvorsky, L Gremer, D Willbold, L Schmitt, ... Journal of Biological Chemistry 291 (51), 26364-26376, 2016 | 42 | 2016 |
Biophysical characterization of nucleophosmin interactions with human immunodeficiency virus rev and herpes simplex virus US11 K Nouri, JM Moll, LG Milroy, A Hain, R Dvorsky, E Amin, M Lenders, ... PloS one 10 (12), e0143634, 2015 | 35 | 2015 |
A genome-wide CRISPR/Cas9 screen in acute myeloid leukemia cells identifies regulators of TAK-243 sensitivity SH Barghout, A Aman, K Nouri, Z Blatman, K Arevalo, GE Thomas, ... JCI insight 6 (5), 2021 | 29 | 2021 |
New model for the interaction of IQGAP1 with CDC42 and RAC1 K Nouri, DJ Timson, MR Ahmadian Small GTPases 11 (1), 16-22, 2017 | 29 | 2017 |
Nanoluciferase complementation-based bioreporter reveals the importance of N-linked glycosylation of SARS-CoV-2 S for viral entry T Azad, R Singaravelu, Z Taha, TR Jamieson, S Boulton, MJF Crupi, ... Molecular Therapy 29 (6), 1984-2000, 2021 | 28 | 2021 |
Implications for SARS-CoV-2 vaccine design: Fusion of spike glycoprotein transmembrane domain to receptor-binding domain induces trimerization T Azad, R Singaravelu, MJF Crupi, T Jamieson, J Dave, EEF Brown, ... Membranes 10 (9), 215, 2020 | 28 | 2020 |
Intracellular GTP level determines cell's fate toward differentiation and apoptosis A Meshkini, R Yazdanparast, K Nouri Toxicology and applied pharmacology 253 (3), 188-196, 2011 | 27 | 2011 |
Proliferation inhibition, cell cycle arrest and apoptosis induced in HL-60 cells by a natural diterpene ester from Daphne mucronata K Nouri, R Yazdanparast Daru: Journal of Faculty of Pharmacy, Tehran University of Medical Sciences …, 2011 | 23 | 2011 |
Mitochondrial ATP-dependent proteases—Biological function and potential anti-cancer targets Y Feng, K Nouri, AD Schimmer Cancers 13 (9), 2020, 2021 | 20 | 2021 |
Storage conditions, sample integrity, interferences, and a decision tool for investigating unusual high-sensitivity cardiac troponin results MA Lafrenière, V Tandon, C Ainsworth, K Nouri, SE Mondoux, A Worster, ... Clinical Biochemistry 115, 67-76, 2023 | 18 | 2023 |
Monitoring Hippo signaling pathway activity using a luciferase-based large tumor suppressor (LATS) biosensor T Azad, K Nouri, HJJ van Rensburg, Y Hao, X Yang Journal of Visualized Experiments: Jove, 58416, 2018 | 15 | 2018 |