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Kazem Nouri
Kazem Nouri
Department of Pathology and Laboratory Medicine, Vancouver General Hospital, BC, Canada
Verified email at medportal.ca
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Year
Juvenile myelomonocytic leukemia displays mutations in components of the RAS pathway and the PRC2 network
A Caye, M Strullu, F Guidez, B Cassinat, S Gazal, O Fenneteau, E Lainey, ...
Nature genetics 47 (11), 1334-1340, 2015
1932015
Functional dysregulation of CDC42 causes diverse developmental phenotypes
S Martinelli, OHF Krumbach, F Pantaleoni, S Coppola, E Amin, ...
The American Journal of Human Genetics 102 (2), 309-320, 2018
1802018
Deciphering the molecular and functional basis of RHOGAP family proteins: a systematic approach toward selective inactivation of RHO family proteins
E Amin, M Jaiswal, U Derewenda, K Reis, K Nouri, KT Koessmeier, ...
Journal of Biological Chemistry 291 (39), 20353-20371, 2016
1222016
Mitochondrial ClpP serine protease-biological function and emerging target for cancer therapy
K Nouri, Y Feng, AD Schimmer
Cell death & disease 11 (10), 841, 2020
932020
Subcellular fractionation and localization studies reveal a direct interaction of the fragile X mental retardation protein (FMRP) with nucleolin
MS Taha, K Nouri, LG Milroy, JM Moll, C Herrmann, L Brunsveld, ...
PloS one 9 (3), e91465, 2014
742014
Identification of Celastrol as a Novel YAP-TEAD Inhibitor for Cancer Therapy by High Throughput Screening with Ultrasensitive YAP/TAZ–TEAD Biosensors
K Nouri, T Azad, M Ling, HJJ van Rensburg, A Pipchuk, H Shen, Y Hao, ...
Cancers 11 (10), 1596, 2019
662019
A gain-of-functional screen identifies the Hippo pathway as a central mediator of receptor tyrosine kinases during tumorigenesis
T Azad, K Nouri, HJJ van Rensburg, SM Maritan, L Wu, Y Hao, ...
Oncogene 39 (2), 334-355, 2019
632019
The centrosomal adaptor TACC3 and the microtubule polymerase chTOG interact via defined C-terminal subdomains in an Aurora-A kinase-independent manner
HC Thakur, M Singh, L Nagel-Steger, J Kremer, D Prumbaum, EK Fansa, ...
Journal of Biological Chemistry 289 (1), 74-88, 2014
532014
A kinome-wide screen using a NanoLuc LATS luminescent biosensor identifies ALK as a novel regulator of the Hippo pathway in tumorigenesis and immune evasion
K Nouri, T Azad, E Lightbody, P Khanal, CJ Nicol, X Yang
The FASEB Journal 33 (11), 12487, 2019
442019
IQGAP1 interaction with RHO family proteins revisited: kinetic and equilibrium evidence for multiple distinct binding sites
K Nouri, EK Fansa, E Amin, R Dvorsky, L Gremer, D Willbold, L Schmitt, ...
Journal of Biological Chemistry 291 (51), 26364-26376, 2016
422016
Biophysical characterization of nucleophosmin interactions with human immunodeficiency virus rev and herpes simplex virus US11
K Nouri, JM Moll, LG Milroy, A Hain, R Dvorsky, E Amin, M Lenders, ...
PloS one 10 (12), e0143634, 2015
352015
A genome-wide CRISPR/Cas9 screen in acute myeloid leukemia cells identifies regulators of TAK-243 sensitivity
SH Barghout, A Aman, K Nouri, Z Blatman, K Arevalo, GE Thomas, ...
JCI insight 6 (5), 2021
292021
New model for the interaction of IQGAP1 with CDC42 and RAC1
K Nouri, DJ Timson, MR Ahmadian
Small GTPases 11 (1), 16-22, 2017
292017
Nanoluciferase complementation-based bioreporter reveals the importance of N-linked glycosylation of SARS-CoV-2 S for viral entry
T Azad, R Singaravelu, Z Taha, TR Jamieson, S Boulton, MJF Crupi, ...
Molecular Therapy 29 (6), 1984-2000, 2021
282021
Implications for SARS-CoV-2 vaccine design: Fusion of spike glycoprotein transmembrane domain to receptor-binding domain induces trimerization
T Azad, R Singaravelu, MJF Crupi, T Jamieson, J Dave, EEF Brown, ...
Membranes 10 (9), 215, 2020
282020
Intracellular GTP level determines cell's fate toward differentiation and apoptosis
A Meshkini, R Yazdanparast, K Nouri
Toxicology and applied pharmacology 253 (3), 188-196, 2011
272011
Proliferation inhibition, cell cycle arrest and apoptosis induced in HL-60 cells by a natural diterpene ester from Daphne mucronata
K Nouri, R Yazdanparast
Daru: Journal of Faculty of Pharmacy, Tehran University of Medical Sciences …, 2011
232011
Mitochondrial ATP-dependent proteases—Biological function and potential anti-cancer targets
Y Feng, K Nouri, AD Schimmer
Cancers 13 (9), 2020, 2021
202021
Storage conditions, sample integrity, interferences, and a decision tool for investigating unusual high-sensitivity cardiac troponin results
MA Lafrenière, V Tandon, C Ainsworth, K Nouri, SE Mondoux, A Worster, ...
Clinical Biochemistry 115, 67-76, 2023
182023
Monitoring Hippo signaling pathway activity using a luciferase-based large tumor suppressor (LATS) biosensor
T Azad, K Nouri, HJJ van Rensburg, Y Hao, X Yang
Journal of Visualized Experiments: Jove, 58416, 2018
152018
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