| The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-β F Martinon, K Burns, J Tschopp Molecular cell 10 (2), 417-426, 2002 | 7218 | 2002 |
| Gout-associated uric acid crystals activate the NALP3 inflammasome F Martinon, V Pétrilli, A Mayor, A Tardivel, J Tschopp Nature 440 (7081), 237-241, 2006 | 6073 | 2006 |
| The inflammasomes: guardians of the body F Martinon, A Mayor, J Tschopp Annual review of immunology 27 (1), 229-265, 2009 | 3081 | 2009 |
| NALP3 forms an IL-1β-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder L Agostini, F Martinon, K Burns, MF McDermott, PN Hawkins, J Tschopp Immunity 20 (3), 319-325, 2004 | 2121 | 2004 |
| Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration V Petrilli, S Papin, C Dostert, A Mayor, F Martinon, J Tschopp Cell Death & Differentiation 14 (9), 1583-1589, 2007 | 1759 | 2007 |
| Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases F Martinon, J Tschopp Cell 117 (5), 561-574, 2004 | 1272 | 2004 |
| RIP1 is an essential mediator of Toll-like receptor 3–induced NF-κB activation E Meylan, K Burns, K Hofmann, V Blancheteau, F Martinon, M Kelliher, ... Nature immunology 5 (5), 503-507, 2004 | 1141 | 2004 |
| TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages F Martinon, X Chen, AH Lee, LH Glimcher Nature immunology 11 (5), 411-418, 2010 | 1080 | 2010 |
| Inflammatory caspases and inflammasomes: master switches of inflammation F Martinon, J Tschopp Cell Death & Differentiation 14 (1), 10-22, 2007 | 1062 | 2007 |
| NALPs: a novel protein family involved in inflammation J Tschopp, F Martinon, K Burns Nature reviews Molecular cell biology 4 (2), 95-104, 2003 | 997 | 2003 |
| NLRs join TLRs as innate sensors of pathogens F Martinon, J Tschopp Trends in immunology 26 (8), 447-454, 2005 | 856 | 2005 |
| MyD88, an adapter protein involved in interleukin-1 signaling K Burns, F Martinon, C Esslinger, H Pahl, P Schneider, JL Bodmer, ... Journal of biological chemistry 273 (20), 12203-12209, 1998 | 807 | 1998 |
| The caspase-8 inhibitor FLIP promotes activation of NF-κB and Erk signaling pathways T Kataoka, RC Budd, N Holler, M Thome, F Martinon, M Irmler, K Burns, ... Current biology 10 (11), 640-648, 2000 | 742 | 2000 |
| Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor K Burns, J Clatworthy, L Martin, F Martinon, C Plumpton, B Maschera, ... Nature cell biology 2 (6), 346-351, 2000 | 720 | 2000 |
| Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome F Martinon, L Agostini, E Meylan, J Tschopp Current Biology 14 (21), 1929-1934, 2004 | 711 | 2004 |
| Signaling by ROS drives inflammasome activation F Martinon European journal of immunology 40 (3), 616-619, 2010 | 705 | 2010 |
| The unfolded protein response: integrating stress signals through the stress sensor IRE1α C Hetz, F Martinon, D Rodriguez, LH Glimcher Physiological reviews 91 (4), 1219-1243, 2011 | 693 | 2011 |
| Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response JA Kummer, R Broekhuizen, H Everett, L Agostini, L Kuijk, F Martinon, ... Journal of Histochemistry & Cytochemistry 55 (5), 443-452, 2007 | 661 | 2007 |
| A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses A Mayor, F Martinon, T De Smedt, V Pétrilli, J Tschopp Nature immunology 8 (5), 497-503, 2007 | 560 | 2007 |
| STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity O Demaria, A De Gassart, S Coso, N Gestermann, J Di Domizio, L Flatz, ... Proceedings of the National Academy of Sciences 112 (50), 15408-15413, 2015 | 552 | 2015 |
Kay HofmannProfessor of Genetics, University of CologneVerified email at uni-koeln.de