The role of protein dynamics in the evolution of new enzyme function E Campbell, M Kaltenbach, GJ Correy, PD Carr, BT Porebski, ... Nature chemical biology 12 (11), 944-950, 2016 | 307 | 2016 |
Evolution of chalcone isomerase from a noncatalytic ancestor M Kaltenbach, JR Burke, M Dindo, A Pabis, FS Munsberg, A Rabin, ... Nature chemical biology 14 (6), 548-555, 2018 | 141 | 2018 |
On the potential origins of the high stability of reconstructed ancestral proteins DL Trudeau, M Kaltenbach, DS Tawfik Molecular biology and evolution 33 (10), 2633-2641, 2016 | 141 | 2016 |
Dynamics and constraints of enzyme evolution M Kaltenbach, N Tokuriki Journal of Experimental Zoology Part B: Molecular and Developmental …, 2014 | 92 | 2014 |
Reverse evolution leads to genotypic incompatibility despite functional and active site convergence M Kaltenbach, CJ Jackson, EC Campbell, F Hollfelder, N Tokuriki Elife 4, e06492, 2015 | 83 | 2015 |
GroEL/ES buffering and compensatory mutations promote protein evolution by stabilizing folding intermediates KT Wyganowski, M Kaltenbach, N Tokuriki Journal of molecular biology 425 (18), 3403-3414, 2013 | 78 | 2013 |
A simple method to evaluate the biochemical compatibility of oil/surfactant mixtures for experiments in microdroplets M Kaltenbach, SRA Devenish, F Hollfelder Lab on a Chip 12 (20), 4185-4192, 2012 | 38 | 2012 |
An experimental framework for improved selection of binding proteins using SNAP display G Houlihan, P Gatti-Lafranconi, M Kaltenbach, D Lowe, F Hollfelder Journal of Immunological Methods 405, 47-56, 2014 | 35 | 2014 |
SNAP dendrimers: Multivalent protein display on dendrimer‐like DNA for directed evolution M Kaltenbach, V Stein, F Hollfelder Chembiochem 12 (14), 2208-2216, 2011 | 35 | 2011 |
Functional trade-offs in promiscuous enzymes cannot be explained by intrinsic mutational robustness of the native activity M Kaltenbach, S Emond, F Hollfelder, N Tokuriki PLoS genetics 12 (10), e1006305, 2016 | 33 | 2016 |
SNAP display: in vitro protein evolution in microdroplets M Kaltenbach, F Hollfelder Ribosome Display and Related Technologies: Methods and Protocols, 101-111, 2011 | 26 | 2011 |
Generation of effective libraries by neutral drift M Kaltenbach, N Tokuriki Directed Evolution Library Creation: Methods and Protocols, 69-81, 2014 | 17 | 2014 |
Droplets as reaction compartments for protein nanotechnology SRA Devenish, M Kaltenbach, M Fischlechner, F Hollfelder Protein Nanotechnology: Protocols, Instrumentation, and Applications, Second …, 2013 | 15 | 2013 |
Bifunctional substrate activation via an arginine residue drives catalysis in chalcone isomerases JR Burke, JJ La Clair, RN Philippe, A Pabis, M Corbella, JM Jez, ... ACS Catalysis 9 (9), 8388-8396, 2019 | 14 | 2019 |
Publisher Correction: Evolution of chalcone isomerase from a noncatalytic ancestor. M Kaltenbach, JR Burke, M Dindo, A Pabis, FS Munsberg, A Rabin, ... Nature Chemical Biology 14 (10), 988-988, 2018 | 2 | 2018 |
Assembling linear DNA templates for in vitro transcription and translation V Stein, M Kaltenbach, F Hollfelder Functional Genomics: Methods and Protocols, 67-78, 2012 | 1 | 2012 |
Structural Characterization of the Emergence and Evolution of Catalysis in the Chalcone Isomerase Family Fold J Burke, M Kaltenbach, D Tawfik, J Noel The FASEB Journal 30, lb112-lb112, 2016 | | 2016 |
In vitro selection and evolution of DARPins using SNAP display G Houlihan, P Gatti-Lafranconi, M Kaltenbach, D Lowe, F Hollfelder FEBS JOURNAL 280, 471-471, 2013 | | 2013 |